Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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New aspects of the innate immune system in the infant born prematurely. Searching for new risk factors of neonatal sepsis

2012/07/B/NZ5/01221

Keywords:

Prematurity sespis innate immunity inflammasome interleukin-1-beta monocyte IRA-B cells

Descriptors:

  • NZ5_1: Etiology of human diseases
  • NZ5_3: Pathogenesis of human diseases
  • NZ5_5: Diagnostics in human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Przemko Kwinta 

Number of co-investigators in the project: 7

Call: OPUS 4 - announced on 2012-09-15

Amount awarded: 286 580 PLN

Project start date (Y-m-d): 2013-07-02

Project end date (Y-m-d): 2017-07-01

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Komputer osobisty - laptop (5 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (6)
  1. Inflammasome function in monocyte subsets and a risk of late-onset sepsis in preterm very low birth weight neonates
    Authors:
    Zasada Magdalena; Lenart Marzena; Rutkowska-Zapała Magdalena; Stec Małgorzata; Czyz Ola; Mól Nina; Siedlar Maciej; Kwinta Przemko
    Academic press:
    Minerva Pediatrica (rok: 2018, ), Wydawca: EDIZIONI MINERVA MEDICA
    Status:
    Accepted for publication
    DOI:
    10.23736/S0026-4946.18.05034-X - link to the publication
  2. Analysis of PD-1 expression in the monocyte subsets from non-septic and septic preterm neonates
    Authors:
    Zasada Magdalena; Lenart Marzena; Rutkowska-Zapała Magdalena; Stec Małgorzata, Durlak Wojciech; Grudzień Andrzej; Krzeczkowska Agnieszka; Mól Nina; Pilch Marta; Siedlar Maciej; Kwinta Przemko
    Academic press:
    PLOS One (rok: 2017, tom: 12, strony: e0186819), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0186819 - link to the publication
  3. Analysis of inflammasome function in the blood monocytes from neonates born extremely and very prematurely
    Authors:
    Magdalena Zasada, Marzena Lenart, Magdalena Rutkowska-Zapała, Małgorzata Stec, Nina Mól, Maciej Siedlar, Przemko Kwinta
    Academic press:
    Immunobiology (rok: 2018, tom: 223, strony: 18-24), Wydawca: Elsevier
    Status:
    Published
  4. Rola limfocytów IRA B w wybranych procesach zapalnych
    Authors:
    Magdalena Zasada, Magdalena Rutkowska-Zapała, Marzena Lenart, Przemko Kwinta
    Academic press:
    Postepy Hig Med Dosw (rok: 2016, tom: 70, strony: 194-199), Wydawca: Index Copernicus International, Warszawa
    Status:
    Published
    DOI:
    10.5604/17322693.1197370 - link to the publication
  1. Expression of programmed death-1 receptors in subsets of monocytes from children born with birth weight ≤1500g,
    Authors:
    M Zasada, M Lenart, M Rutkowska-Zapała, JJ Pietrzyk, M Siedlar, P Kwinta,
    Conference:
    Hot Topics in Neonatology (rok: 2016, ), Wydawca: Neomours Conference Materials
    Data:
    konferencja 5-7.12.2016
    Status:
    Published
  2. Functional analysis of blood mono- cytes in neonates with birth weight ≤ 1,500
    Authors:
    M. Zasada, M. Lenart, M. Rutkowska-Zapała, N. Mól, M. Siedlar, P. Kwinta
    Conference:
    6th International Congress of UENPS 2016 (rok: 2017, ), Wydawca: Hygeia Press di Corridori Marinella
    Data:
    konferencja 23-25.11.2016
    Status:
    Published
  3. Evaluation of the relationship between monocyte numbers and functions and the risk of late-onset sepsis in preterm infants
    Authors:
    Kwinta P., Zasada M., Lenart M., Rutkowska-Zapała M., Pietrzyk J.J., Siedlar M.
    Conference:
    Hot Topics in Neonatology (rok: 2014, ), Wydawca: Journal of Perinatal-Neonatal Medicine
    Data:
    konferencja 6-10 grudnia
    Status:
    Published
  4. Evaluation of the relationship between inflammasomes' functions and the risk of late-onset sepsis in preterm infants
    Authors:
    Zasada M., Kwinta P., Lenart M., Rutkowska-Zapała M., Pietrzyk J.J., Siedlar M.
    Conference:
    1st Congress of joint European Neonatal Societies (jENS 2015) (rok: 2015, ), Wydawca: ESPR https://www.eiseverywhere.com/file_uploads/2f9db64d0134ef7d7549387be9d5f412_PosterBook_4aug15.pdf
    Data:
    konferencja 16-20 wrzesień
    Status:
    Published
  5. Is the Risk of Late-Onset Sepsis Associated with Impaired Inflammasome Function in Very Low Birth Weight Newborns?
    Authors:
    Kwinta P., Zasada M, Lenart M, Rutkowska-Zapała M, Pietrzyk J.J., Siedlar M.
    Conference:
    Hot Topics in Neonatology (rok: 2015, ), Wydawca: Nemours Conference Materials http://www.nemconfsyllabus.com/HTNPosters2015.html
    Data:
    konferencja 6-9 grudzień
    Status:
    Published
  6. Inflammasome function in monocytes from very low birth weight children and its relationship with the subsequent development of late-onset sepsis
    Authors:
    M Zasada, M Lenart, M Rutkowska-Zapała, JJ Pietrzyk, M Siedlar, P Kwinta,
    Conference:
    Hot Topics in Neonatology (rok: 2016, ), Wydawca: Nemours Conference Materials
    Data:
    konferencja 5-7.12.2016
    Status:
    Published