Projects funded by the NCN
Polychlorinated naphtalens as an endocrine disruptors in the ovary
2012/07/N/NZ7/01142
Keywords:
PCN ovary steroidogenesis receptors
Descriptors:
- NZ7_2: Environment and health risks
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi, Instytut Zoologii
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 4 - announced on 2012-09-15
Amount awarded: 99 970 PLN
Project start date (Y-m-d): 2013-09-13
Project end date (Y-m-d): 2015-09-12
Project duration:: 24 months (the same as in the proposal)
Project status: Project settled
Information in the final report
- Publication in academic press/journals (2)
- Effects of individual polychlorinated naphthalene (PCN) components of Halowax 1051 and two defined, artificial PCN mixtures on AHR and CYP1A1 protein expression, steroid secretion and expression of enzymes involved in steroidogenesis (CYP17, 17β-HSD and CYP19) in porcine ovarian follicles.Authors:Barć J, Gregoraszczuk EŁAcademic press:Toxicology (rok: 2014, tom: 322, strony: 14-22), Wydawca: nie dotyczyStatus:PublishedDOI:10.1016/j.tox.2014.04.010 - link to the publication
- Halowax 1051 affects steroidogenesis by down-regulation of aryl hydrocarbon and estrogen receptors and up-regulation of androgen receptor in porcine ovarian follicles.Authors:Barć J, Gregoraszczuk ELAcademic press:Chemosphere (rok: 2015, tom: 144, strony: 467-474), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.chemosphere.2015.09.026 - link to the publication