Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Establishment of a novel scientific workshop enabling complex analysis of RNA degradome - elaboration of innovative methods for the identification of RNA degradants and the assessment of their functional potential

2012/05/D/NZ2/02238

Keywords:

RNA degradome regulatory RNA deep sequencing libraries HCV

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ2_7: Bioinformatics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Instytut Chemii Bioorganicznej PAN

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Paulina Jackowiak 

Number of co-investigators in the project: 4

Call: SONATA 3 - announced on 2012-03-15

Amount awarded: 406 900 PLN

Project start date (Y-m-d): 2013-03-01

Project end date (Y-m-d): 2016-08-31

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zasilacz wysokonapięciowy (10 000 PLN)
  2. Aparat do elektroforezy dwukierunkowej RNA (osobny moduł do rozdziału w jednym i drugim kierunku) (8 000 PLN)
  3. Termostat chłodząco-grzejący z recyrkulatorem (21 000 PLN)
  4. laptop.

Information in the final report

  • Publication in academic press/journals (7)
  • Articles in post-conference publications (3)
  1. RNA-Seq-based analysis of differential gene expression associated with hepatitis C virus infection in a cell culture
    Authors:
    A. Hojka-Osinska, L. Budzko, A. Zmienko, A. Rybarczyk, P. Maillard, A. Budkowska, M. Figlerowicz, P. Jackowiak
    Academic press:
    Acta Biochimica Polonica (rok: 2016, tom: 63(4), strony: 789-798), Wydawca: Polish Biochemical Society and Committee of Biochemistry and Biophysics Polish Academy of Sciences
    Status:
    Published
    DOI:
    10.18388/abp.2016_1343 - link to the publication
  2. Small RNA fragments derived from multiple RNA classes – the missing element of multi-omics characteristics of the hepatitis C virus cell culture model
    Authors:
    P. Jackowiak, A, Hojka-Osinska, A. Philips, A. Zmienko, L. Budzko, P. Maillard, A. Budkowska, M. Figlerowicz
    Academic press:
    BMC Genomics (rok: 2017, tom: 18, strony: 502), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s12864-017-3891-3 - link to the publication
  3. Protein interactome of small RNA fragments: identification and functional implications
    Authors:
    P. Jackowiak, A. Lis, M. Luczak, M. Figlerowicz
    Academic press:
    Journal of Proteomics (rok: 2018, tom: -, strony: -), Wydawca: Elsevier
    Status:
    Submitted
    DOI:
    brak - link to the publication
  4. Phylogeny and molecular evolution of the hepatitis C virus
    Authors:
    P. Jackowiak, K. Kuls, L. Budzko, A. Mania, M. Figlerowicz, M. Figlerowicz
    Academic press:
    Infection, Genetics and Evolution (rok: 2014, tom: 21, strony: 67-82), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.021 - link to the publication
  5. Effects of G-quadruplex topology on translational inhibition by tRNA fragments in mammalian and plant systems in vitro
    Authors:
    P. Jackowiak, A. Hojka-Osinska, K. Gasiorek, M. Stelmaszczuk, D. Gudanis, Z. Gdaniec, M. Figlerowicz
    Academic press:
    The International Journal of Biochemistry & Cell Biology (rok: 2017, tom: 92, strony: 148-154), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.001 - link to the publication
  6. Identification of stable, high copy number, medium-sized RNA degradation intermediates that accumulate in plants under non-stress conditions
    Authors:
    M. Nowacka, P. M. Strozycki, P. Jackowiak, A. Hojka-Osinska, M. Szymanski, M. Figlerowicz
    Academic press:
    Plant Molecular Biology (rok: 2013, tom: 83(3), strony: 191-204), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s11103-013-0079-3 - link to the publication
  7. Mutations in human AID differentially affect its ability to deaminate cytidine and 5-methylcytidine in ssDNA substrates in vitro
    Authors:
    L. Budzko, P. Jackowiak, K. Kamel, J. Sarzynska, J.M. Bujnicki, M. Figlerowicz
    Academic press:
    Scientific Reports (rok: 2017, tom: 7, strony: 3873), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-017-03936-x - link to the publication
  1. Structural requirements of translational inhibition by tRNA fragments in vitro
    Authors:
    P. Jackowiak, A. Hojka-Osinska, K. Sowinska, M. Stelmaszczuk, M. Figlerowicz
    Conference:
    BIO 2016 Congress (rok: 2016, ), Wydawca: Polish Biochemical Society
    Data:
    konferencja 13-16.09 2016
    Status:
    Published
    DOI:
    link to the publication
  2. Identification of novel non-coding RNAs in human cells infected with hepatitis C virus
    Authors:
    P. Jackowiak, A. Hojka-Osińska, A. Philips, A. Żmieńko, L. Budzko, P. Maillard, A. Budkowska, M. Figlerowicz
    Conference:
    BIO 2014 Congress (rok: 2014, ), Wydawca: Polish Biochemical Society and Committee of Biochemistry and Biophysics Polish Academy of Sciences
    Data:
    konferencja 9-12.09.2014
    Status:
    Published
    DOI:
    link to the publication
  3. Short RNAs derived from multiple RNA classes are as abundant as miRNA in human cells infected with hepatitis C virus
    Authors:
    P. Jackowiak, A. Hojka-Osinska, A. Philips, A. Zmienko, L. Budzko, P. Maillard, A. Budkowska, M. Figlerowicz
    Conference:
    20th Annual Meeting of the RNA Society (rok: 2015, ), Wydawca: RNA Society
    Data:
    konferencja 25-31.05.2015
    Status:
    Published

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