Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Applying systems biology approach for analysis of the glucose signalling pathways in yeast

2012/05/E/NZ2/00583

Keywords:

transcription glycosysis gluconeogenesis systems biology

Descriptors:

  • NZ2_9: Systems biology
  • NZ2_4: Metabolomics
  • NZ2_1: Molecular genetics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Politechnika Warszawska, Wydział Chemiczny

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Małgorzata Adamczyk 

Number of co-investigators in the project: 4

Call: SONATA BIS 1 - announced on 2012-03-15

Amount awarded: 764 000 PLN

Project start date (Y-m-d): 2013-03-13

Project end date (Y-m-d): 2017-03-12

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. BioFlo/CelliGen 115 stołowy, laboratoryjny bioreactor (68 780 PLN)
  2. Homogenizator kulowy do drożdży (BeadBeater) (6 000 PLN)
  3. Wirówka stołowa z chłodzeniem Eppendorf 5430R (dwa wymienne rotory) (27 000 PLN)
  4. Kołyska laboratoryjna.
  5. Inkubator z wytrząsaniem.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. Low RNA polymerase III activity results in up regulation of HXT2 glucose transporter independently of glucose signaling and despite changing environment
    Authors:
    Malgorzata Adamczyk, Roza Szatkowska
    Academic press:
    PLosOne (rok: 2017, tom: 12(9), strony: e0185516), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0185516 - link to the publication
  2. Glycolytic flux in Saccharomyces cerevisiae is dependent on RNA polymerase III and its negative regulator Maf1
    Authors:
    Roza Szatkowska, Manuel Garcia-Albornoz, Katarzyna Roszkowska, Stephen W Holman, Emil Furmanek, Simon J Hubbard, Robert Jeffrey Beynon, Małgorzata Adamczyk
    Academic press:
    Biochemical Journal (rok: 2019, tom: 476, strony: 1053-1082), Wydawca: Portland Press
    Status:
    Published
    DOI:
    10.1042/BCJ20180701 - link to the publication
  3. Fructose bisphosphate aldolase is involved in the control of RNA polymerase III-directed transcription.
    Authors:
    Cieśla M1, Mierzejewska J2, Adamczyk M2, Farrants AK3, Boguta M4.
    Academic press:
    Biochim Biophys Acta (rok: 2014, tom: 1843(6), strony: 1103-10), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2014.02.007 - link to the publication
  1. Carbon flow through tricarboxylic acid cycle (TCA) is changed in yeast strains with altered RNA Polymerase III activity
    Authors:
    Roza Szatkowaska, Christian Ludwig, Malgorzata Adamczyk
    Conference:
    Horizons in Molecular Biology (rok: 2018, ), Wydawca: Cuvillier Verlang
    Data:
    konferencja 10-13 września
    Status:
    Published
    DOI:
    link to the publication

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