Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

The role of autophagy in pathogenesis of diabetic nephropathy; regulation of podocyte autophagy by insulin-dependent ROS production.

2012/05/N/NZ5/00808

Keywords:

autophagy diabetic nephropathy insulin podocytes reactive oxygen species

Descriptors:

  • NZ1_1: Molecular biology
  • NZ3_1: Cell biology
  • NZ4_4: Pathophysiology

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Irena Audzeyenka 

Number of co-investigators in the project: 2

Call: PRELUDIUM 3 - announced on 2012-03-15

Amount awarded: 149 890 PLN

Project start date (Y-m-d): 2013-03-11

Project end date (Y-m-d): 2016-03-10

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (3)
  1. Reactive oxygen species are involved in insulin-dependent regulation of autophagy in primary rat podocytes.
    Authors:
    Audzeyenka I, Rogacka D, Piwkowska A, Rychlowski M, Bierła JB, Czarnowska E, Angielski S, Jankowski M.
    Academic press:
    International Journal of Biochemistry & Cell Biology (rok: 2016, tom: 75, strony: 23-33), Wydawca: Elsevier Ltd.
    Status:
    Published
    DOI:
    10.1016/j.biocel.2016.03.015 - link to the publication
  1. Autophagy regulation in podocytes by insulin-dependent ROS production.
    Authors:
    Audzeyenka I, Rogacka D, Piwkowska A, Angielski S, Jankowski M.
    Conference:
    48. Zjazd Polskiego Towarzystwa Biochemicznego, 2-5 września 2013r, Toruń. (rok: 2013, ), Wydawca: Panstwowe Wydawnictwo Naukowe
    Data:
    konferencja 2-5 września
    Status:
    Published
  2. Insulin modulates the expression and activity of autophagic proteins in rat podocytes.
    Authors:
    Audzeyenka I, Piwkowska A, Rogacka D, Angielski S, Jankowski M.
    Conference:
    10th International Podocyte Conference (rok: 2014, ), Wydawca: Nephron Clinical Practice
    Data:
    konferencja 4-6 czerwca
    Status:
    Published
  3. Activation of podocyte autophagy by insulin-dependent ROS production.
    Authors:
    Audzeyenka I, Rogacka D, Piwkowska A, Angielski S, Jankowski M.
    Conference:
    BIO 2014 Congress (rok: 2014, ), Wydawca: Panstwowe Wydawnictwo Naukowe
    Data:
    konferencja 9-12 września
    Status:
    Published