Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Molecular mechanisms of neuromuscular junction development

2012/05/E/NZ3/00487

Keywords:

neuromuscular synapse development plasticity podosome AChR muscle

Descriptors:

  • NZ3_5: Molecular neurobiology
  • NZ3_6: Cell neurobiology
  • NZ3_1: Cell biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Tomasz Prószyński 

Number of co-investigators in the project: 4

Call: SONATA BIS 1 - announced on 2012-03-15

Amount awarded: 1 500 000 PLN

Project start date (Y-m-d): 2013-08-01

Project end date (Y-m-d): 2018-05-31

Project duration:: 58 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Maszyna do PCR (2 szt.) (28 000 PLN)
  2. Komputer stacjonarny (3 szt.) (18 000 PLN)
  3. Spektrofotometr do pomiarów koncentracji DNA (10 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (16)
  1. Hippo signaling pathway transcription coactivator YAP is localized to podosomes/invadopodia in Src-transformed NIH-3T3 fibroblasts
    Authors:
    Patrycja E. Daszczuk i Tomasz J. Prószyński
    Academic press:
    Science Matters (rok: 2016, tom: 1, strony: brak), Wydawca: Science Matters
    Status:
    Published
  2. LL5β interacts with uncharacterized protein 2410002F23Rik (LL5BIP).
    Authors:
    Paweł Niewiadomski i Tomasz J. Prószyński
    Academic press:
    Science Matters (rok: 2016, tom: 1, strony: brak), Wydawca: Science Matters
    Status:
    Published
  3. Involvement of unconventional myosin VI in myoblast function and myotube formation
    Authors:
    Karolczak J, Pavlyk I, Majewski Ł, Sobczak M, Niewiadomski P, Rzhepetskyy Y, Sikorska A, Nowak N, Pomorski P, Prószyński T, Ehler E, Rędowicz MJ
    Academic press:
    Histochemistry and Cell Biology (rok: 2015, tom: 144, strony: 21-38), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00418-015-1322-6 - link to the publication
  4. Podosomes in muscle cells and their role in the remodeling of neuromuscular postsynaptic machinery
    Authors:
    Bernadzki KM, Rojek KO, Prószyński TJ
    Academic press:
    European Journal of Cell Biology (rok: 2014, tom: 93, strony: 478-485), Wydawca: Elsever
    Status:
    Published
    DOI:
    10.1016/j.ejcb.2014.06.002 - link to the publication
  5. Amot and Yap1 Regulate Neuronal Dendritic Tree Complexity and Locomotor Coordination in Mice
    Authors:
    Katarzyna O Rojek, Joanna Krzemień, Hubert Doleżyczek, Paweł M Boguszewski, Leszek Kaczmarek, Witold Konopka, Marcin Rylski, Jacek Jaworski, Lars Holmgren, Tomasz J Prószyński
    Academic press:
    PLOS Biology (rok: 2019, tom: 17, strony: Plos Biology), Wydawca: PLOS
    Status:
    Published
    DOI:
    10.1371/journal.pbio.3000253 - link to the publication
  1. Jak powstajπ precle? Badania nad molekularnπ maszyneriπ sterującą rozwojem synaps
    Authors:
    Tomasz Prószyński
    Conference:
    Symbioza 2015 (rok: 2015, ), Wydawca: Uniwersytet Warszawski
    Data:
    konferencja 29-31 maja 2015
    Status:
    Published
  2. Angiomotins, a novel family of proteins involved in neuronal networks organization
    Authors:
    Katarzyna Rojek, Joanna Krzemień, Hubert Doleżyczek, Marcin Rylski, Leszek Kaczmarek, Jacek Jaworski, Tomasz Prószyński
    Conference:
    EMBO Conference Cell Biology of the Neuron: Polarity, Plasticity and Regeneration" (rok: 2017, ), Wydawca: EMBO
    Data:
    konferencja 07-10.05
    Status:
    Published
  3. EXPRESSION AND FUNCTION OF ANGIOMOTIN FAMILY PROTEINS IN THE BRAIN
    Authors:
    Tomasz Prószyński, Katarzyna Rojek, Paweł Niewiadomski, Krzysztof Bernadzki, Hubert Dolężyczek, Marcin Rylski, Leszek Kaczmarek, Jacek Jaworski
    Conference:
    12th International Congress of PNS (rok: 2015, ), Wydawca: Acta Neurobiologiae Axperimentalis
    Data:
    konferencja 6-8 wrzesień 2015
    Status:
    Published
  4. Liprin-α-1 is a novel component of the neuromuscular junction and involved in the organization of the postysynaptic machinery.
    Authors:
    Krzysztof M. Bernadzki, Marcin Pęziński, Marta Gawor, Paula Mazurek, Paweł Niewiadomski, Jolanta Rędowicz, and Tomasz J. Prószyński
    Conference:
    PTBUN 2017 (rok: 2017, ), Wydawca: PTBUN
    Data:
    konferencja 28-31 sierpnia
    Status:
    Published
  5. ROLE OF Amotl2, Rassf8 AND Homer1 IN THE ORGANIZATION OF POSTSYNAPTIC MACHINERY
    Authors:
    Marta Gawor, Paweł Niewiadomski, Krzysztof Bernadzki, Jolanta Jóźwiak, Katarzyna Rojek, Maria Jolanta Rędowicz, Tomasz J. Prószyński
    Conference:
    12th International Congress of PNS (rok: 2015, ), Wydawca: Acta Neurobiologiae Axperimentalis
    Data:
    konferencja 6-8 wrzesień 2015
    Status:
    Published
  6. SH3BP2 as a novel scaffold protein regulating muscle postsynaptic machinery
    Authors:
    Krzysztof Marian Bernadzki, Marta Gawor, Paweł Niewiadomski, Bhola Shankar Pradhan and Tomasz Jacek Prószyński
    Conference:
    14th IIM meeting (rok: 2017, ), Wydawca: 14th IIM meeting
    Data:
    konferencja 12-15 października
    Status:
    Published
  7. Amotl2 and Homer1 – novel regulators of the postsynaptic machinery organization
    Authors:
    Marta Gawora, Paweł Niewiadomskia, Anna Protasiuka , Bhola Shankar Pradhana, Maria Jolanta Rędowiczb and Tomasz Jacek Prószyńskia
    Conference:
    14th IIM meeting (rok: 2017, ), Wydawca: 14th IIM meeting
    Data:
    konferencja 12-15 października
    Status:
    Published
  8. Angiomotin, a novel protein involved in organization of dendritic arbors
    Authors:
    Katarzyna Rojek1, Joanna Krzemień1, Hubert Doleżyczek2, Marcin Rylski3, Leszek Kaczmarek2, Jacek Jaworski4, Tomasz Prószyński
    Conference:
    EMBO Dendrites 2018: Dendritic anatomy, molecules and function (rok: 2018, ), Wydawca: EMBO
    Data:
    konferencja 17 – 20 czerwca
    Status:
    Published
  9. How to build a tree: the function of Angiomotin family of proteins in the brain
    Authors:
    Joanna Krzemień, Katarzyna Rojek, Paweł Niewiadomski, Krzysztof M. Bernadzki, Hubert Doleżyczek, Marcin Rylski, Leszek Kaczmarek, Jacek Jaworski, Tomasz Prószyński
    Conference:
    Aspects of Neuroscience 2016 (rok: 2016, ), Wydawca: Uniwersytet Warszawski
    Data:
    konferencja 25-27.11.2016
    Status:
    Published
  10. Spatial distribution of neuromuscular junction components. Pretzels are more complex than we have anticipated.
    Authors:
    Marta Gawor, Paweł Niewiadomski, Krzysztof Bernadzki, Tomasz Prószyński
    Conference:
    FENS 2016 (rok: 2016, ), Wydawca: FENS
    Data:
    konferencja 02-06.07.2016
    Status:
    Published
  11. Angiomotins, a novel family of proteins with important functions in the brain
    Authors:
    Katarzyna Rojek, Joanna Krzemień, Paweł Niewiadomski, Krzysztof M. Bernadzki, Hubert Doleżyczek, Marcin Rylski, Leszek Kaczmarek, Jacek Jaworski, Tomasz Prószyński
    Conference:
    FENS 2016 (rok: 2016, ), Wydawca: FENS
    Data:
    konferencja 02-06.07.2016
    Status:
    Published
  12. Spatial distribution of neuromuscular junction components. Pretzels are more complex than we have anticipated
    Authors:
    Gawor M., PhD, Niewiadomski P. PhD, Daszczuk P. MSc, Prószyński T.J.
    Conference:
    Molecular and Cellular Biology of the Neuromuscular System (rok: 2016, ), Wydawca: Szwajcaria
    Data:
    konferencja 18-23.09.2016
    Status:
    Published
  13. The molecular machinery for pretzel formation at the neuromuscular junction
    Authors:
    Paweł Niewiadomski, Marta Gawor, Krzysztof Bernadzki, Jolanta Jóźwiak, Katarzyna Rojek, Maria Jolanta Rędowicz, Tomasz Prószyński
    Conference:
    44th European Muscle Conference (rok: 2015, ), Wydawca: J Muscle Res Cell Motil
    Data:
    konferencja 21-25 września 2015
    Status:
    Published
  14. Expression and function of Angiomotin family of proteins in the brain
    Authors:
    Katarzyna Rojek, Paweł Niewiadomski, Krzysztof Bernadzki, Hubert Doleżyczek, Marcin Rylski, Leszek Kaczmarek, Jacek Jaworski, Tomasz Prószyński
    Conference:
    EMBO Young Scientists Forum 2015 (rok: 2015, ), Wydawca: YSF 2015 Book of Abstracts
    Data:
    konferencja 2-3 lipca 2015
    Status:
    Published
  15. More Than A Pretzel: Spatial Distribution Of The Neuromuscular Junction Components.
    Authors:
    Marta Gawor, PhD, Paweł Niewiadomski, PhD, Patrycja Daszczuk, MSc, Krzysztof Bernadzki, MSc, Tomasz J. Prószyński, PhD
    Conference:
    Conference Name: 13th International Conference on Myasthenia Gravis and Related Disorders (rok: 2017, ), Wydawca: NYAS
    Data:
    konferencja 15-17 maja
    Status:
    Published
  16. Spatial distribution of neuromuscular junction components. Pretzels are more complex than we have anticipated
    Authors:
    Tomasz Prószyński
    Conference:
    2016 Padua Muscle Days (rok: 2016, ), Wydawca: Eur J Transl Myol - Basic Appl Myol 2016; 26 (1): str. 42
    Data:
    konferencja 14-16.04.2016
    Status:
    Published