Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Investigation of neuroprotective potency and mechanism of action of opioid-neurotensin hybrid peptides in organotypic hippocampal culture after excitotoxic injury-challenge.

2011/03/N/NZ4/02417

Keywords:

neuroprotection opioid-neurotensin hybrids hippocampus

Descriptors:

  • NZ3_5: Molecular neurobiology
  • NZ3_7: Signal transduction
  • NZ4_7: Neurophysiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Patrycja Kleczkowska 

Number of co-investigators in the project: 3

Call: PRELUDIUM 2 - announced on 2011-09-15

Amount awarded: 308 600 PLN

Project start date (Y-m-d): 2012-08-20

Project end date (Y-m-d): 2014-08-19

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. binokular (19 862 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (3)
  1. Effects of the hybridization of opioid and neurotensin pharmacophores on cell survival in rat organotypic hippocampal slice cultures.
    Authors:
    Kleczkowska P.*, Kawalec M., Bujalska-Zadrozny M., Filip M., Zablocka B., Lipkowski A.W
    Academic press:
    Neurotoxicity Research (rok: 2015, tom: 28, strony: 352-360), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12640-015-9553-9 - link to the publication
  1. Effects of the hybridization of opioid and neurotensin pharmacophores on neurotoxicity in hippocampal organotypic cultures
    Authors:
    Patrycja Kleczkowska, Maria Kawalec, Barbara Zablocka, Andrzej W. Lipkowski
    Conference:
    10th Australian International Peptide Conference (rok: 2013, ), Wydawca: Australian Peptide Association
    Data:
    konferencja 8-13 wrzesień
    Status:
    Published
    DOI:
    link to the publication
  2. Effects of the hybridization of opioid and neurotensin pharmacophores on neurotoxicity in hippocampal organotypic cultures
    Authors:
    Patrycja Kleczkowska, Maria Kawalec, Barbara Zablocka, Andrzej W. Lipkowski
    Conference:
    22nd Polish Peptide Symposium (rok: 2013, ), Wydawca: Wrocław
    Data:
    konferencja 1-5 wrzesień
    Status:
    Published
  3. Effects of the hybridization of opioid and neurotensin pharmacophores on neurotoxicity in hippocampal organotypic cultures
    Authors:
    Kleczkowska Patrycja, Kawalec Maria, Zablocka Barbara, Lipkowski Andrzej W.
    Conference:
    8th Annual Drug Discovery for Neurodegeneration Conference (rok: 2014, ), Wydawca: Alzheimer's Drug Discovery Foundation
    Data:
    konferencja 02-04.02
    Status:
    Published

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