Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Hydrogen exchange mass spectrometry (HXMS) for studying human serum amyloid A fibril formation.

2011/03/N/NZ5/01460

Keywords:

serum amyloid A (SAA) hydrogen-deuterium exchange mass spectrometry (HXMS) native chemical ligation (NCL) amyloid formation short peptides as inhibitors of protein/polypeptide aggregation

Descriptors:

  • ST5_23:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Gdański, Wydział Chemii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Marta Sosnowska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 2 - announced on 2011-09-15

Amount awarded: 190 612 PLN

Project start date (Y-m-d): 2012-10-10

Project end date (Y-m-d): 2015-02-09

Project duration:: 28 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Kolektor frakcji Gilson FC 204; (22 800 PLN)
  2. Wytrząsarka do kolb o ruchu oscylacyjnym, SF1; 2 ramiona robocze i 8 uchwytów (7 500 PLN)
  3. Mieszadło magnetyczne, 1-stanowisk., Big Squid Ikamag EUCH (850 PLN)
  4. pH-metr laboratoryjny, Lab 850 zestaw, mikroelektroda kombinowana pH, Blueline, 16 pH (4 900 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  1. Designing peptidic inhibitors of serum amyloid A aggregation process
    Authors:
    Marta Sosnowska, Sandra Skibiszewska, Emilia Kamińska, Ewa Wieczerzak, Elżbieta Jankowska
    Academic press:
    Amino Acids (rok: 2016, tom: Online First, strony: pp1-10), Wydawca: Springer Vienna
    Status:
    Published
    DOI:
    10.1007/s00726-015-2167-y - link to the publication