Quantitative assessment of vascular endothelial growth factor (VEGF) in serum, follicular fluid (FF) and VEGF mRNA in granulosa cells (GS) as risk factors of ovarian hyperstimulation syndrome (OHSS) occurrence in controlled ovarian hyperstimulation protocols (COH) which use gonadotropin-releasing hormone (GnRH) antagonists or agonists, and in natural cycle oocyte retrieval protocol.

2011/01/B/NZ5/05373

Keywords

Descriptors

  • NZ5_5: Diagnostyka chorób człowieka

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Artur Jacek Jakimiuk

Number of co-investigators in the project: 7

Call

OPUS 1 – announced on 2011-03-15

Amount awarded
597 155 PLN
Project start date
2011-12-08
Project end date
2015-12-07
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (2)

  1. High levels of soluble vascular endothelial growth factor receptor 1/sFLT1 and low levels of vascular endothelial growth factor in follicular fluid on the day of oocyte retrieval correlate with ovarian hyperstimulation syndrome regardless of the stimulation protocol

    Authors:
    A.J. Jakimiuk, M.A. Nowicka, M. Zagozda, K. Kozioł, P. Lewandowski, T. Issat
    Academic press:
    Journal of Physiology and Pharmatology (year: 2017, volume: 68(3), pages: 477-484), Publisher: Department of Physiology Jagiellonian University Medical College, Kraków
    Status:
    Published
    DOI:
    link to the publication
  2. Levels of EG-VEGF and VEGF in serum and in the follicular fluid on the day of oocyte retrieval and reproductive outcome among IVF patients.

    Authors:
    Artur J. Jakimiuk, Malgorzata A. Nowicka, Malgorzata Zagozda, Katarzyna Koziol, Piotr Lewandowski, Tadeusz Issat
    Status:
    Accepted for publication

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