Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Quantitative assessment of vascular endothelial growth factor (VEGF) in serum, follicular fluid (FF) and VEGF mRNA in granulosa cells (GS) as risk factors of ovarian hyperstimulation syndrome (OHSS) occurrence in controlled ovarian hyperstimulation protocols (COH) which use gonadotropin-releasing hormone (GnRH) antagonists or agonists, and in natural cycle oocyte retrieval protocol.

2011/01/B/NZ5/05373

Keywords:

ovarian hyperstimulation syndrome (OHSS) vascular endothelial growth factor (VEGF) mRNA VEGF mRNA EG-VEGF Prokinectin 1 S VEGFr1/FLT1,controlled ovarian hyperstimulation protocols (COH) human chorionic gonadotropin (hCG) gonadotropin-releasing hormone (GnRH),GnRH antagonist GnRH agonist

Descriptors:

  • NZ5_5: Diagnostics in human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Artur Jakimiuk 

Number of co-investigators in the project: 7

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 597 155 PLN

Project start date (Y-m-d): 2011-12-08

Project end date (Y-m-d): 2015-12-07

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  1. Levels of EG-VEGF and VEGF in serum and in the follicular fluid on the day of oocyte retrieval and reproductive outcome among IVF patients.
    Authors:
    Artur J. Jakimiuk, Malgorzata A. Nowicka, Malgorzata Zagozda, Katarzyna Koziol, Piotr Lewandowski, Tadeusz Issat
    Academic press:
    Clinical and Experimental Obstetrics & Gynecology (rok: 2016, ), Wydawca: Irog.net
    Status:
    Accepted for publication
  2. High levels of soluble vascular endothelial growth factor receptor 1/sFLT1 and low levels of vascular endothelial growth factor in follicular fluid on the day of oocyte retrieval correlate with ovarian hyperstimulation syndrome regardless of the stimulation protocol
    Authors:
    A.J. Jakimiuk, M.A. Nowicka, M. Zagozda, K. Kozioł, P. Lewandowski, T. Issat
    Academic press:
    Journal of Physiology and Pharmatology (rok: 2017, tom: 68(3), strony: 477-484), Wydawca: Department of Physiology Jagiellonian University Medical College, Kraków
    Status:
    Published