Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Confirmation of the role of individual genes involved in the pathogenesis of bronchial asthma with hypersensitivity to aspirin at the level of RNA and protein expression

2011/01/N/NZ5/00334

Keywords:

hypersensitivity to aspirin asthma induced by aspirin cyclooxygenase leukotriens

Descriptors:

  • NZ5_1: Etiology of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny w Łodzi

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Dorota Kacprzak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 1 - announced on 2011-03-15

Amount awarded: 99 875 PLN

Project start date (Y-m-d): 2011-12-01

Project end date (Y-m-d): 2013-11-30

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (2)
  1. The whole-genome expression analysis of peripheral blood mononuclear cells from aspirin sensitive asthmatics versus aspirin tolerant patients and healthy donors after in vitro aspirin challenge.
    Authors:
    Wieczfinska J, Kacprzak D, Pospiech K, Sokolowska M, Nowakowska M, Pniewska E, Bednarek A, Kuprys-Lipinska I, Kuna P, Pawliczak R.
    Academic press:
    Respiratory Research (rok: 2015, tom: 16, strony: 15), Wydawca: BioMedCentral
    Status:
    Published
    DOI:
    10.1186/s12931-015-0305-4 - link to the publication
  1. Aspirin downregulates FOSL1 disrupting pulmonary protection in aspirin induced asthma
    Authors:
    D.Kacprzak, J.Wieczfinska, K.Pospiech, M.Nowakowska, AK Bednarek, E.Pniewska, R.Pawliczak
    Conference:
    EAACI Congress 2014 (rok: 2014, ), Wydawca: -
    Data:
    konferencja 7-11.06.2014
    Status:
    Accepted for publication
  2. Increased oxidative stress and apoptosis susceptibility in peripheral blood mononuclear cells from aspirin sensitive asthmatics in comparison to aspirin tolerant asthmatics and healthy volunteers
    Authors:
    D.Kacprzak, J.Wieczfinska, E.Pniewska, R.Pawliczak
    Conference:
    ERS International Congress 2014 (rok: 2014, ), Wydawca: European Respiratory Journal
    Data:
    konferencja 6-10.09.2014
    Status:
    Published