Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Primary biliary cirrhosis (PBC) in Poland - clinical characteristics, analysis of relationship between genetic and molecular variants and disease phenotypes and search for prognostic factors. A mulicentre, prospective study.

2011/01/B/NZ5/05291

Keywords:

liver cirrhosis autoimmunity genetics prognostic factors

Descriptors:

  • NZ2_1: Molecular genetics
  • NZ6_2: Clinical immunology

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Andrzej Habior 

Number of co-investigators in the project: 38

Call: OPUS 1 - announced on 2011-03-15

Amount awarded: 1 274 000 PLN

Project start date (Y-m-d): 2011-12-19

Project end date (Y-m-d): 2014-12-18

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. wniosek nie przewidywał zakupu aparatury i zadnego zakupu nie dokonano.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (5)
  1. A novel approach to genome-wide association analysis identifies genetic associations with primary biliary cholangitis and primary sclerosing cholangitis in Polish patients
    Authors:
    Agnieszka Paziewska, Andrzej Habior ,Agnieszka Rogowska, Wlodzimierz Zych, Krzysztof Goryca, Jakub Karczmarski, Michalina Dabrowska, Filip Ambrozkiewicz, Bozena Walewska-Zielecka, Marek Krawczyk, Halina Cichoz-Lach, Piotr Milkiewicz, Agnieszka Kowalik, Krzysztof Mucha, Joanna Raczynska, Joanna Musialik, Grzegorz Boryczka, Michal Wasilewicz, Irena Ciecko-Michalska, Malgorzata Ferenc, Maria Janiak, Alina Kanikowska, Rafal Stankiewicz, Marek Hartleb, Tomasz Mach, Marian Grzymislawski, Joanna Raszeja-Wyszomirska, Ewa Wunsch, Tomasz Bobinski, Michal Mikula, Jerzy Ostrowski
    Academic press:
    BMC Medical Genomics (rok: 2017, tom: 0,418055555555556, strony: 45300), Wydawca: Biomed Central
    Status:
    Published
    DOI:
    10.1186/s12920-016-0239-9 - link to the publication
  2. Clinical applicability of whole-exome sequencing exemplified by a study in young adults with the advanced cryptogenic cholestatic liver diseases
    Authors:
    Maria Kulecka, Andrzej Habior, Agnieszka Paziewska, Krzysztof Goryca, Michalina Dąbrowska, Filip Ambrozkiewicz, Bożena Walewska-Zielecka, Andrzej Gabriel, Michal Mikula, Jerzy Ostrowski
    Academic press:
    Gastroenterology Research and Practice (rok: 2017, tom: 2017, strony: 45319), Wydawca: Hindawi Publishing Corporation
    Status:
    Accepted for publication
  3. Primary biliary cirrhosis in the era of liver transplantation
    Authors:
    Raczyńska J., Habior A., Pączek L., Foroncewicz B., Pawełas A., Mucha K.
    Academic press:
    Annals of Transplantation (rok: 2014, tom: 19, strony: 488-493), Wydawca: International Scientific Literature, New York, USA
    Status:
    Published
    DOI:
    10.12659/AOT.890753 - link to the publication
  1. AUTOANTIBODIES DIRECTED AGAINST COMPONENTS OF PROMYELOCYTIC LEUKEMIA PROTEIN NUCLEAR BODIES IN PATIENTS WITH PRIMARY BILIARY CIRRHOSIS
    Authors:
    Bauer, A.; Habior, A.; Zych, W.; Rawa, T.
    Conference:
    Euromedlab Milano 2013, 20th IFCC - EFLM European Congress of Clinical Chemistry and Laboratory Medicine, 45th Congress of the Italian Society of Clinical Biochemistry and Clinical Molecular Biology (SIBoC), (rok: 2013, ), Wydawca: Biochimica Clinica
    Data:
    konferencja 19-23 maja
    Status:
    Published
  2. Diagnostic and clinical significance of specific antibodies and biochemical parameters in the primary biliary cirrhosis. Study of patients from Poland. (prezentacja ustna)
    Authors:
    Alicja Bauer, Tomasz Rawa, Damian Gaweł, Andrzej Habior
    Conference:
    4th Joint EFLM-UEMS Congress "Laboratory Medicine at the Clinical Interface", (rok: 2016, ), Wydawca: Clinical Chemistry and Laboratory Medicine
    Data:
    konferencja 21-24 September
    Status:
    Published
  3. Serum levels of interleukin-6 and interleukin-8 in patients with primary biliary cirrhosis.
    Authors:
    Alicja Bauer, Andrzej Pawełas, Andrzej Habior.
    Conference:
    9th International Congress on Autoimmunity, Nice, France (rok: 2014, ), Wydawca: International Association of Autoimmunity
    Data:
    konferencja 26-30 March
    Status:
    Published
  4. Antinuclear autoantibodies in serum of patients with primary biliary cirrhosis.
    Authors:
    Alicja Bauer, Andrzej Habior.
    Conference:
    21 IFCC - EFLM European Congress of Clinical Chemistry and Laboratory Medicine, France, Paris, 21-25 June 2015 (rok: 2015, ), Wydawca: Clinical Chemistry and Laboratory Medicine
    Data:
    konferencja 21-25 June
    Status:
    Published
  5. Autoantibody anti-Sp140 in primary biliary cirrhosis (prezentacja ustna)
    Authors:
    Alicja Bauer, Andrzej Habior, Tomasz Rawa, Włodzimierz Zych
    Conference:
    15 Kongres Polskiego Towarzystwa Gastroenterologii (rok: 2012, ), Wydawca: Gastroenterologia Polska
    Data:
    konferencja 4-6 października
    Status:
    Published