Fitness effects of protein instability in the model eukaryotic cells of Saccharomyces cerevisiae.

2011/01/B/NZ8/00042

Keywords

Descriptors

  • NZ8_1: Biologia ewolucyjna
  • NZ8_9: Genetyka populacyjna
  • NZ8_8: Ekotoksykologia

Panel

NZ8 – Evolutionary and environmental biology: evolution, ecology, population biology, biodiversity, biogeography

Host institution

Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Katarzyna Tomala

Number of co-investigators in the project: 4

Call

OPUS 1 – announced on 2011-03-15

Amount awarded
192 800 PLN
Project start date
2011-12-09
Project end date
2014-12-08
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. autoklaw medyczny. Cost: 6 500 PLN
  2. automatyczna pipeta wielokanałowa wraz ze statywem ładującym. Cost: 6 710 PLN
  3. inkubator z chłodzeniem. Cost: 14 000 PLN
  4. pipety wielokanałowe (2 pcs). Cost: 2 000 PLN

Information in the final report

Publication in academic press/journals (2)

  1. Fitness Costs of Minimal Sequence Alterations Causing Protein Instability and Toxicity

    Authors:
    Katarzyna Tomala, Elzbieta Pogoda, Agata Jakubowska, Ryszard Korona
    Academic press:
    Molecular Biology and Evolution (year: 2014, volume: 31 (3), pages: 703-707), Publisher: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/molbev/mst264 – link to the publication
  2. Evaluating the Fitness Cost of Protein Expression in Saccharomyces cerevisiae

    Authors:
    Katarzyna Tomala, Ryszard Korona
    Academic press:
    Genome Biology and Evolution (year: 2013, volume: 5 (11), pages: 2051-2060), Publisher: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/gbe/evt154 – link to the publication

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