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Specific effects evaluation of the selected polimorphisms of GCK, GCKR, G6PC2/ABCB11, MTNR1B and ACE genes on the metabolic compensation of type 1 diabetes in children with established residual β-cell function.

2011/01/N/NZ5/01357

Keywords:

type 1 diabetes children genetic polimorphism disease progression GCK GCKR G6PC2/ABCB11 MTNR1B ACE

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ5_5: Diagnostics in human diseases
  • NZ5_7: Human disease treatment

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Gdański Uniwersytet Medyczny, Wydział Lekarski

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Małgorzata Pawłowicz 

Number of co-investigators in the project: 6

Call: PRELUDIUM 1 - announced on 2011-03-15

Amount awarded: 157 839 PLN

Project start date (Y-m-d): 2011-12-01

Project end date (Y-m-d): 2016-05-31

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. w projekcie nie zaplanowano zakupu lub wytworzenia aparatury naukowo - badawczej.

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (4)
  1. The ACE rs4340 polymorphism as genetic modulator of gender-specific trends in diabetic ketoacidosis development at onset of type 1 diabetes in children
    Authors:
    Małgorzata Pawłowicz, Rafał Filipów, Grzegorz Krzykowski, Julia Kulczycka, Anna Balcerska, Joanna Wojtkiewicz
    Academic press:
    Polish Annals of Medicine (rok: 2019, tom: 26, strony: 41-47), Wydawca: Uniwersytet Warmińsko-Mazurski w Olsztynie
    Status:
    Published
    DOI:
    10.29089/2017.17.00062 - link to the publication
  1. Joint Effects of Selected GCK and FCRL3 Polymorphisms on Dynamics of Residual β-Cells Function in Children with Early Clinical Phase of Type 1 Diabetes
    Authors:
    Pawłowicz Małgorzata, Morzuch Lucyna, Stanisławska-Sachadyn Anna, Filipów Rafał, Krzykowski Grzegorz, Kulczycka Julia, Balcerska Anna, Limon Janusz
    Conference:
    Fifth Meeting of the EASD Study Group on Genetics of Diabetes (EASD-SGGD), 7-9th May 2015, Krakow, Poland. (rok: 2015, ), Wydawca: EASD Study Group on Genetics of Diabetes
    Data:
    konferencja 7-9.05.2015
    Status:
    Published
  2. Selected genetic aspects of type 1 diabetes incidence and clinical course of disease among children - Europe vs. Pomeranian region of Poland
    Authors:
    Małgorzata Pawłowicz
    Conference:
    Interdisciplinary Public Health Seminar Diabetes and obesity: Current understanding and perspectives for 2030 (rok: 2015, ), Wydawca: ISPED
    Data:
    konferencja 23.01.2015
    Status:
    Published
  3. Specific Effects of Selected Demographic and Genetic Factors on Diagnostic Delays in Children with New-Onset Type 1 Diabetes from Pomeranian Region of Poland
    Authors:
    Pawłowicz Małgorzata, Morzuch Lucyna, Stanisławska-Sachadyn Anna, Filipów Rafał, Krzykowski Grzegorz, Kulczycka Julia
    Conference:
    7th Europaediatrics Congress 13-16 May 2015 Florence, Italy (rok: 2015, ), Wydawca: European Paediatric Association (EPA/UNEPSA)
    Data:
    konferencja 13-16.05.2015
    Status:
    Published
  4. Association of Selected GCK and GCKR Polymorphisms with Early Clinical Course of Type 1 Diabetes in Children with Saved Residual β-Cells Function
    Authors:
    Pawłowicz Małgorzata, Stanisławska-Sachadyn Anna, Filipów Rafał, Krzykowski Grzegorz, Morzuch Lucyna, Kulczycka Julia, Balcerska Anna, Limon Janusz
    Conference:
    Immunology of Diabetes Society 14th International Congress 12-16 April 2015, Munich, Germany (rok: 2015, ), Wydawca: Immunology of Diabetes Society, Elsevier
    Data:
    konferencja 12-16.04.2015
    Status:
    Published

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