Projects funded by the NCN

Targeting MMP-9 in Cancer Treatment: Computational Design and Experimental Validation of Potent, Safe Antitumor Agents

Call: SONATA BIS 15 , Panel: ST5

Principal investigator: dr Anna Żądło-Dobrowolska

Instytut Chemii Organicznej Polska Akademia Nauk

Raman spectroscopy guided assessment of vascular niche microenvironmentinfluence on leukemic myeloid progenitors and leu...

Call: OPUS 29 , Panel: ST4

Principal investigator: dr Adriana Justyna Adamczyk

Uniwersytet Jagielloński

Hybrid surface treatments of titanium alloys for biomedical applications

Call: PRELUDIUM 24 , Panel: ST11

Principal investigator: Agnieszka Kowalczyk

Politechnika Warszawska

Developing an AI algorithm for longitudinal tracking of post-treatment changes in brain metastases using a hybrid Uncert...

Call: PRELUDIUM 24 , Panel: NZ7

Principal investigator: Monika Żaneta Pytlarz

Sano - Centrum Zindywidualizowanej Medycyny Obliczeniowej - Międzynarodowa Fundacja Badawcza

Studies on new generation of processes for degradation of environmental pollutants

Call: OPUS 29 , Panel: ST8

Principal investigator: dr hab. Grzegorz Piotr Boczkaj

Politechnika Gdańska

Flavonoid phytoprogestins as novel non-steroidal progesterone receptor modulators in a nutraceutical approach to endomet...

Call: PRELUDIUM 24 , Panel: NZ9

Principal investigator: Agata Gołąbek-Grenda

Uniwersytet Przyrodniczy w Poznaniu

Dual-acting 5-HT6/5-HT7 receptor antagonists: exploring beneficial effects for the treatment of neurodegenerative disord...

Call: PRELUDIUM 24 , Panel: NZ7

Principal investigator: Michał Kamiński

Uniwersytet Jagielloński

Application of probiotic extracellular vesicles in the treatment of chronic wounds with concomitant fungal infection.

Call: PRELUDIUM 24 , Panel: NZ6

Principal investigator: Katarzyna Daria Kowalik

Uniwersytet Jagielloński

The impact of H3 histamine receptor modulation on oligodendrogenesis and neurogenesis: a new strategy for the treatment ...

Call: PRELUDIUM 24 , Panel: NZ5

Principal investigator: Maciej Degutis

Instytut Farmakologii PAN

Valorization of macroalgae biomass by thermochemical processes in the context of agricultural and environmental applicat...

Call: OPUS 29 , Panel: NZ9

Principal investigator: prof. Izabela Magdalena Michalak

Politechnika Wrocławska

Multidimensional analysis of the gut microbiome, including the virome,archaeome, bacteriome, and mycobiome,along with ge...

Call: OPUS 29 , Panel: NZ4

Principal investigator: dr Agnieszka Aleksandra Krawczyk

Uniwersytet Jagielloński

Astrocytic contributions to endogenous neuroprotection: Can astrocytes point the way to neuroprotective treatments?

Call: OPUS 29 , Panel: NZ5

Principal investigator: dr hab. Małgorzata Beręsewicz-Haller

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Smart Multiscale Encapsulation System: Hydrogel Macrocapsules with LbL Nanoparticles for Colorectal Cancer Treatment

Call: PRELUDIUM 24 , Panel: ST11

Principal investigator: Joanna Irena Szechyńska

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Deposition and characterization of superhard and superlubricant tungsten boride with addition of transition metals (W,TM...

Call: PRELUDIUM 24 , Panel: ST11

Principal investigator: Rafał Andrzej Psiuk

Instytut Podstawowych Problemów Techniki Polska Akademia Nauk

New aryl difluoromethylenephosphonic acid and thiazole conjugates as effective PTP1B inhibitors used in the treatment of...

Call: PRELUDIUM 24 , Panel: ST5

Principal investigator: Dominika Agnieszka Kołodziej-Sobczak

Uniwersytet Mikołaja Kopernika

Self-Assembled Flexible Uniform-Pore Catalytic Membranes for Treating Refractory Organic Pollutants in Industrial Wastew...

Call: SHENG 4 , Panel: ST5

Principal investigator: dr hab. Paweł Wawrzyniec Majewski

Uniwersytet Warszawski

Synthesis and Functionalization of Hyperbranched Polypeptides for Osteoarthritis Treatment

Call: SHENG 4 , Panel: ST11

Principal investigator: dr hab. Monika Gosecka

Centrum Badań Molekularnych i Makromolekularnych PAN

Preparation of pollen-like advanced drug delivery carriers for the treatment of chronic obstructive pulmonary disease

Call: SHENG 4 , Panel: ST5

Principal investigator: prof. Elżbieta Pamuła

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie

Artificial intelligence in predicting treatment outcomes of abdominal cancers – implementation of machine learning and d...

Call: SONATINA 9 , Panel: NZ7

Principal investigator: dr Krzysztof Bartnik

Politechnika Warszawska

Next-Generation Exosome Therapy: Engineering NK Cell-Derived Vesicles for Targeted Cancer Treatment

Call: SONATINA 9 , Panel: NZ6

Principal investigator: dr Daria Nawrocka

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Developing histone deacetylase-inhibiting hybrid analogs of pleurocidin and their potential in the treatment of HPV-indu...

Call: SONATA 20 , Panel: NZ7

Principal investigator: dr hab. Ewelina Piktel

Uniwersytet Medyczny w Białymstoku

Light-responsive biowaste-based sustainable 3D platform withon-demand drug release against bacterial infections in acute...

Call: SONATA 20 , Panel: ST5

Principal investigator: dr Alicja Kosik-Kozioł

Instytut Podstawowych Problemów Techniki Polska Akademia Nauk

Antibacterial molecules based on bacteriophage proteins and constant antibody fragments with therapeutic potential for t...

Call: SONATA 20 , Panel: NZ7

Principal investigator: dr Karolina Aleksandra Filik-Matyjaszczyk

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

The application of biopolymeric materials prepared with water exposed to indirect plasma treatment in the encapsulation ...

Call: SONATA 20 , Panel: NZ9

Principal investigator: dr Żaneta Anna Król-Kilińska

Uniwersytet Przyrodniczy we Wrocławiu

Reduction of the inflammatory state in keratinocytes using cholesterol-enriched polymer fibers with a controlled piezoel...

Call: SONATA 20 , Panel: ST11

Principal investigator: dr Krzysztof Łukasz Berniak

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie

Research and analysis of the degradation process of microplastics as a result of the treatment of digested sewage sludge...

Call: OPUS 28 , Panel: ST8

Principal investigator: dr hab. Małgorzata Maria Wilk

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie

A triple agonist of glucagon, GLP-1, and GIP receptors as a novel therapeutic option for the treatment of heart failure ...

Call: SONATA 20 , Panel: NZ5

Principal investigator: dr Marta Katarzyna Oknińska

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

Selective autophagy-mediated protein degradation as a potential therapeutic strategy for the treatment of inflammatory c...

Call: OPUS 28 , Panel: NZ7

Principal investigator: dr hab. Monika Emilia Marcinkowska

Uniwersytet Jagielloński

(Bio)functionalized mineral and organic adsorbent-based floating islands as a nature-based, passive treatment system for...

Call: OPUS 28 , Panel: ST10

Principal investigator: prof. Tomasz Piotr Bajda

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie

Biotechnological method for production of 8-prenylnaringenin for application in treatment of inflammatory skin diseases

Call: SONATA 20 , Panel: ST8

Principal investigator: dr Jan Paweł Krzysztoforski

Politechnika Warszawska

"Integrated Fixed-Dose Combination Drugs in Depression Therapy: A New Standard of Treatment and Mechanism of Action Stud...

Call: OPUS 28 , Panel: NZ7

Principal investigator: prof. Gabriel Piotr Nowak

Instytut Farmakologii PAN

Non-canonical Estrogen Receptor (ER) signalling in breast cancer progression

Call: OPUS 28 , Panel: NZ3

Principal investigator: prof. Rafał Sebastian Sądej

Gdański Uniwersytet Medyczny

Computational and experimental nanodosimetry for proton radiotherapy

Call: WEAVE-UNISONO , Panel: ST2

Principal investigator: dr hab. Antoni Wojciech Ruciński

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego PAN

IgLON5 disease: NeuroInflammatory Tauopathy and Encephalopathy: the Model for Inflammation towards early treatment of Ne...

Call: JPND Call 2024 , Panel: NZ4

Principal investigator: dr Natalia Eleonora Małek-Chudzik

Politechnika Wrocławska

In situ alloying and in situ and heat treatment of Ni-Ti-X alloys using Laser Beam Powder Bed Fusion (PBF-LB)

Call: Polskie Powroty NAWA 2023 , Panel: ST11

Principal investigator: dr Agnieszka Chmielewska-Wysocka

Uniwersytet Kardynała Stefana Wyszyńskiego w Warszawie

Mechanisms of Antidepressant Action of Psilocybin: The Role of 5-HT2B-5-HT1A Receptor Dimerization and GSK-3β Activation...

Call: OPUS 27 , Panel: NZ7

Principal investigator: dr hab. Agata Faron-Górecka

Instytut Farmakologii PAN

The use of non-conventional, non-thermal pretreatment methods and their combinations to shape the physical properties, c...

Call: PRELUDIUM 23 , Panel: NZ9

Principal investigator: Radosław Jacek Bogusz

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie

Targeting REST and KAISO: A Promising Approach for Glioblastoma Treatment

Call: OPUS 27 , Panel: NZ2

Principal investigator: dr hab. Bartosz Stefan Wojtaś

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Identification of circulating biomarkers for monitoring anti-CD19 CAR-T cell treatment response in patients with aggress...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Monika Szelest

Uniwersytet Medyczny w Lublinie

The role of gut microbiota in the treatment of epilepsy: experimental studies

Call: OPUS 27 , Panel: NZ4

Principal investigator: prof. Piotr Wiktor Wlaź

Uniwersytet Marii Curie-Skłodowskiej w Lublinie

A machine learning usage to predict venetoclax efficacy and toxicity in chronic lymphocytic leukemia.

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Dorota Kruk-Kwapisz

Warszawski Uniwersytet Medyczny

Stealth" asparaginases as improved protein drugs for the treatment of childhood acute lymphoblastic leukemia (ALL)

Call: OPUS 27 , Panel: NZ1

Principal investigator: prof. Matthias Bochtler

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Electrospinning as an effective approach to topical delivery of natural compounds with wound healing potential

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Anna Gościniak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

New functional MOF@hydroxyapatite composites for the treatment of bacterial bone infections

Call: PRELUDIUM 23 , Panel: ST11

Principal investigator: Weronika Bodylska-Maj

Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego PAN

Molecular mechanisms underlying the liver injury induced by ulipristal acetate treatment

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Aleksandra Natalia Łupińska

Instytut Rozrodu Zwierząt i Badań Żywności PAN

Compulsive Sexual Behavior Disorder: A Cross-Gender Analysis of Symptomatology, Comorbidity With Other Psychiatric Disor...

Call: SONATINA 8 , Panel: HS6

Principal investigator: dr Ewelina Kowalewska

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

Selective inhibition of Janus kinases for the treatment of autoimmune hepatitis: Translational PK/PD modelling from mole...

Call: SONATA 19 , Panel: NZ7

Principal investigator: dr Artur Świerczek

Uniwersytet Jagielloński, Collegium Medicum

Optogenetic and chemogenetic identification of brain circuits and cellular mechanisms underlying antidepressants resista...

Call: OPUS 26 , Panel: NZ7

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Dietary treatment in genetic mouse model of autism.

Call: OPUS 26 , Panel: NZ4

Principal investigator: dr Bożena Joanna Kuźniewska

Uniwersytet Warszawski, Wydział Biologii

Synthesis, characterization, and evaluation of the biological activity of innovative thermosensitive suppositories compr...

Call: OPUS 26 , Panel: NZ7

Principal investigator: prof. Ewa Olędzka

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny