Projects funded by the NCN


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199 projects found matching your search criteria :

  1. MOLECULAR DETERMINANTS OF SIGNAL PROPAGATION IN THE DELTA AND MU OPIOID RECEPTORS - IN SEARCH FOR ANALGETICS WITH LESS S...

    Call: PRELUDIUM 14 , Panel: NZ2

    Principal investigator: Tomasz Stepniewski

    Uniwersytet Warszawski, Wydział Chemii

  2. Polymorphisms in otolin-1 genes in human and zebrafish - influence on function of the C1q-like domain in biomineralizati...

    Call: PRELUDIUM 14 , Panel: NZ1

    Principal investigator: dr Rafał Hołubowicz

    Politechnika Wrocławska

  3. Novel multi-target ligands of aminergic GPCRs as pharmacological tools to study the pathomechanism of schzophrenia

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Kaczor

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  4. Molecular mechanism of anticancer action of selected NSAIDs as a PPAR gamma receptor agonists in experimental models of ...

    Call: PRELUDIUM 14 , Panel: NZ7

    Principal investigator: Adam Kazberuk

    Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  5. Role of astrocytic NMDA receptors in the regulation of glutamine synthetase activity in cultured mouse astrocytes. Attem...

    Call: PRELUDIUM 14 , Panel: NZ3

    Principal investigator: dr Katarzyna Skowrońska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  6. Structural and functional analysis of the C-terminal region of Germ cell-expressed protein (GceC) from Drosophila melano...

    Call: PRELUDIUM 14 , Panel: NZ1

    Principal investigator: dr Marta Kolonko-Adamska

    Politechnika Wrocławska

  7. STIM proteins as new regulators of NMDA receptor trafficking in neurons

    Call: SONATA BIS 7 , Panel: NZ3

    Principal investigator: dr Joanna Gruszczyńska-Biegała

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  8. New receptors for C-reactive protein recognition - generation, characterization and application towards fast differentia...

    Call: SONATA 13 , Panel: ST5

    Principal investigator: dr Katarzyna Szot-Karpińska

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  9. Small-molecule inhibitors for characterization of the interaction between extracellular domains of Programmed Cell Death...

    Call: MAESTRO 9 , Panel: ST5

    Principal investigator: prof. Tadeusz Holak

    Uniwersytet Jagielloński, Wydział Chemii

  10. Neutral homo- and heteronuclear bismacrocyclic metal complexes as components of interlocked molecules.

    Call: PRELUDIUM 1 , Panel: ST5

    Principal investigator: Iwona Mames

    Instytut Chemii Organicznej Polska Akademia Nauk

  11. Multiscale investigations on polymorphism of the beta2-adrenergic receptor: from molecular-scale processes to heart fail...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Anita Płazińska

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  12. The influence of impairment of extracellular nucleoside and nucleotide signaling on synaptic structure and function in a...

    Call: OPUS 13 , Panel: NZ4

    Principal investigator: dr hab. Agata Adamczyk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  13. Development of unique molecular probes: low-basicity agonists for the study of 5-HT7 receptor function

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Andrzej Bojarski

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  14. Novel ligands of histamine receptor H4 as potential anti-allergic and anti-inflammatory drugs

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Sławomir Filipek

    Uniwersytet Warszawski, Wydział Chemii

  15. Designing and application of synthetic receptors for protein hormones

    Call: OPUS 13 , Panel: ST4

    Principal investigator: dr hab. Piyush Sindhu Sharma

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  16. Host receptors involved in bacteriophage adsorption to Dickeya solani and Pectobacterium parmentieri cells and the ecolo...

    Call: OPUS 13 , Panel: NZ9

    Principal investigator: dr hab. Robert Czajkowski

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  17. Evaluation of the anticancer efficacy of a new chimeric antigen receptor targeting PD-L1 molecule

    Call: OPUS 12 , Panel: NZ6

    Principal investigator: dr hab. Radosław Zagożdżon

    Warszawski Uniwersytet Medyczny, Wydział Lekarski

  18. Molecular modeling of allosteric binding and allosteric-orthosteric coupling in cannabinoid receptor CB1

    Call: PRELUDIUM 12 , Panel: NZ1

    Principal investigator: Jakub Jakowiecki

    Uniwersytet Warszawski, Wydział Chemii

  19. Development of novel light-controllable azobenzene switches as molecular receptors for selective sensing and transport o...

    Call: SONATA 12 , Panel: ST5

    Principal investigator: dr Kajetan Dąbrowa

    Instytut Chemii Organicznej Polskiej Akademii Nauk

  20. The effect of membrane domains on the G protein-lipid interactions

    Call: OPUS 12 , Panel: NZ1

    Principal investigator: dr Agnieszka Polit

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  21. The role of (R,S)-Sulforaphane-induced activation of Nrf2 transcription factor in the regulation of depressive-like beha...

    Call: PRELUDIUM 12 , Panel: NZ4

    Principal investigator: dr Patrycja Pańczyszyn-Trzewik

    Uniwersytet Rzeszowski, Kolegium Nauk Medycznych

  22. Characteristic of plant extracts inhibit the binding of Shiga toxin to Gb3 receptors.

    Call: PRELUDIUM 12 , Panel: NZ1

    Principal investigator: Magdalena Komiażyk-Mikulska

    Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

  23. Molecular identification of signalling pathways activated by receptor kinase CRK5 during senescence and stress response ...

    Call: SONATA 12 , Panel: NZ1

    Principal investigator: dr Paweł Burdiak

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

  24. Piperazine derivatives as active histamine H3 receptor ligands - molecular modeling, synthesis, pharmacological evaluati...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Katarzyna Szczepańska

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  25. Study of the hormonal and molecular mechanisms of tumorigenesis in the interstitial tissue of the male gonad

    Call: OPUS 12 , Panel: NZ4

    Principal investigator: prof. Barbara Bilińska

    Uniwersytet Jagielloński, Wydział Biologii

  26. Impact of palmitoylation on the Zn(II)-dependent interaction between CD4 coreceptor and Lck tyrosine kinase.

    Call: PRELUDIUM 11 , Panel: NZ1

    Principal investigator: Anna Kocyła

    Uniwersytet Wrocławski, Wydział Biotechnologii

  27. Molecular receptors as a tool for studies of interactions agonist/antagonist of H1 - H4 receptors

    Call: PRELUDIUM 11 , Panel: ST5

    Principal investigator: Małgorzata Walczak

    Politechnika Łódzka, Wydział Chemiczny

  28. Structural studies of signaling receptors HVEM/CD160 as potential targets for immunoterapy against melanoma

    Call: SONATA 11 , Panel: NZ1

    Principal investigator: dr Marta Orlikowska

    Uniwersytet Gdański, Wydział Chemii

  29. Molecular propellers, bevel gears and sea anemones - dynamically chiral triarylmethyl derivatives as versatile stereoche...

    Call: OPUS 11 , Panel: ST5

    Principal investigator: dr hab. Marcin Kwit

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  30. The function of EBI2 receptor in human oligodendrocytes and its role in the cuprizone model for demyelination.

    Call: POLONEZ 2 , Panel: NZ3

    Principal investigator: dr Aleksandra Rutkowska

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  31. Studies on the steric structure and stability of the gas-phase complexes of macrocyclic receptors with anions using ion ...

    Call: OPUS 11 , Panel: ST4

    Principal investigator: prof. Witold Danikiewicz

    Instytut Chemii Organicznej Polskiej Akademii Nauk

  32. Comparison of adhesive properties and traction forces in bladder cancer cells of various malignancies cultured on polyme...

    Call: PRELUDIUM 11 , Panel: NZ1

    Principal investigator: Joanna Danilkiewicz

    Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego Polskiej Akademii Nauk

  33. Pochodne azulenu jako bloki budulcowe w konstrukcji selektywnych receptorów anionów

    Call: ETIUDA 4 , Panel: ST5

    Principal investigator: Dawid Lichosyt

    Instytut Chemii Organicznej Polskiej Akademii Nauk

  34. Molecular and functional analysis of interleukin 18 (IL-18) its receptor (IL-18R) and IL-18- binding protein (IL-18BP) i...

    Call: PRELUDIUM 10 , Panel: NZ6

    Principal investigator: Sebastian Wawrocki

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  35. Gene and protein analysis of OPRM1/MOR and OPRK1/KOR opioid receptors expression and neurobiological marker of nerve ter...

    Call: PRELUDIUM 1 , Panel: NZ4

    Principal investigator: Piotr Kupczyk

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

  36. In vitro and in vivo preclinical studies of NaA nanozeolite functionalized with antibodies anti-PSMA and labeled with ra...

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: prof. Anna Lankoff

    Instytut Chemii i Techniki Jądrowej

  37. The role of the neuron-microglia CX3CL1-CX3CR1 and CD200-CD200R protein systems in molecular mechanisms of antipsychotic...

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  38. Molecular mechanism of interactions between GPCRs and G protein.

    Call: PRELUDIUM 10 , Panel: NZ2

    Principal investigator: Stefan Mordalski

    Instytut Farmakologii Polskiej Akademii Nauk

  39. Synthesis and Struktural Characterization of Small-Molecule Probes for the Programmed Death 1/ Programmed Death Ligand 1...

    Call: PRELUDIUM 10 , Panel: ST5

    Principal investigator: Katarzyna Guzik

    Uniwersytet Jagielloński, Wydział Chemii

  40. Molecular mechanisms of nucleic acids receptors signalling regulation by Pellino 3 protein during viral infection.

    Call: SONATA BIS 5 , Panel: NZ3

    Principal investigator: dr hab. Jakub Siednienko

    Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

  41. Interdisciplinary studies into molecular mechanisms of conformational transitions underlying GABAA receptor activation

    Call: MAESTRO 7 , Panel: NZ1

    Principal investigator: prof. Jerzy Mozrzymas

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Lekarski

  42. A virtual screening protocol based on automatically generated structure-based pharmacophore models.

    Call: HARMONIA 7 , Panel: NZ2

    Principal investigator: Stefan Mordalski

    Instytut Farmakologii PAN

  43. Estrogen signaling in male gonad from birth to aging. Study of the molecular mechanisms of cellular processes in mammali...

    Call: SONATA BIS 5 , Panel: NZ4

    Principal investigator: dr hab. Małgorzata Kotula-Balak

    Uniwersytet Jagielloński, Wydział Biologii

  44. Searching for the new lead structures for 5-HT7 serotonin receptor ligands with increased metabolic stability.

    Call: HARMONIA 7 , Panel: NZ7

    Principal investigator: Sabina Podlewska

    Instytut Farmakologii PAN

  45. Synthesis and binding studies of new podands based on 1,8-diaminocarbazole moiety

    Call: PRELUDIUM 9 , Panel: ST5

    Principal investigator: Krzysztof Bąk

    Uniwersytet Warszawski, Wydział Chemii

  46. Metabolic profiling of HIF stabilizers, PPAR agonists and SARMs by means of UPLC-MS/MS.

    Call: PRELUDIUM 9 , Panel: ST4

    Principal investigator: Katarzyna Kowalczyk

    Uniwersytet Warszawski, Wydział Chemii

  47. Rational design and pharmacological characterization of chimeric cyclic opioid peptide analogs targeting multiple recept...

    Call: OPUS 9 , Panel: ST5

    Principal investigator: prof. Anna Janecka

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  48. Synthesis of new glutamate receptors antagonists and extensive investigation of their effect on tumor cells in the prese...

    Call: OPUS 9 , Panel: ST5

    Principal investigator: prof. Maria Bretner

    Politechnika Warszawska, Wydział Chemiczny

  49. Development of a method for the structure prediction of GPCRs complexes with agonists and antagonists, including the lig...

    Call: SONATA 1 , Panel: NZ2

    Principal investigator: dr Michał Koliński

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN