Projects funded by the NCN

LLT1 as a regulator of the immune response and a dual-target immunotherapy approach in colorectal cancer directed at NK ...

Call: OPUS 29 , Panel: NZ6

Principal investigator: dr Marzena Dorota Lenart

Uniwersytet Jagielloński

New Horizons in Cancer Immunotherapy: Blocking LAG-3/FGL1 Interactions

Call: SONATA 20 , Panel: NZ7

Principal investigator: dr Jacek Plewka

Uniwersytet Jagielloński

Investigation of the mechanism of enhanced liposome delivery to tumors and its application for dual target immunotherapy

Call: OPUS 28 , Panel: NZ7

Principal investigator: dr hab. Tomasz Piotr Rygiel

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Small molecule modulators of the tumor necrosis factor alpha signaling pathway for the inhibition of inflammatory proces...

Call: OPUS 27 , Panel: NZ7

Principal investigator: prof. Tadeusz Holak

Uniwersytet Gdański

Controlling the covalent activity of a PD-L1 inhibitors with light

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Wiktor Jan Uzar

Uniwersytet Jagielloński

CAR(dio)-T(oxicity)- Engineered Heart Tissue model for CAR-T cardiotoxicity evaluation

Call: SONATA 19 , Panel: NZ7

Principal investigator: dr Agnieszka Joanna Zimna

Instytut Genetyki Człowieka PAN

Increasing sensitivity to immunotherapy in lung cancer via immunostimulation and modulation of tumor microenvironment

Call: SONATA BIS 13 , Panel: NZ5

Principal investigator: dr Urszula Oleksiewicz

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Spatial Determinants of Immunotherapy Resistance in Cancer

Call: WEAVE-UNISONO , Panel: NZ6

Principal investigator: dr Marcin Tabaka

Instytut Chemii Fizycznej Polskiej Akademii Nauk, Międzynarodowe Centrum Badań Oka

Development of novel anti-cancer immunotherapy against mesothelioma comprising of oncolytic adenovirus vectors armed wit...

Call: SONATA 18 , Panel: NZ7

Principal investigator: dr Łukasz Kuryk

Narodowy Instytut Zdrowia Publicznego - Państwowy Zakład Higieny (NIZP - PZH)

A smart stride for cancer: synergistic effect of co-delivery chemo- andphototherapeutic agents using magneto-fluorescent...

Call: POLONEZ BIS 2 , Panel: NZ7

Principal investigator: dr Prachi Uttam Ghoderao

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Intrinsic tumour radiosensitivity as a marker of chemoradiotherapy-induced immunogenic effects in rectal cancer

Call: PRELUDIUM 21 , Panel: NZ5

Principal investigator: Zuzanna Maria Nowicka

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Use of comparative oncology approach to dissect the PD-1 intrinsic signalling in osteosarcoma. Can dog be the key for ne...

Call: PRELUDIUM 21 , Panel: NZ1

Principal investigator: Katarzyna Joanna Dziubek

Uniwersytet Gdański, Międzynarodowe Centrum Badań nad Szczepionkami Przeciwnowotworowymi

The SAR analysis and synthesis of complex, small molecule PD-1/PD-L1 interaction antagonists

Call: PRELUDIUM 20 , Panel: ST4

Principal investigator: Magdalena Maria Żarnik

Uniwersytet Jagielloński, Wydział Chemii

Molecular and cellular landscape of pulmonary and hepatic metastases of colorectal cancer with potential clinical implic...

Call: PRELUDIUM 20 , Panel: NZ4

Principal investigator: dr Marta Aleksandra Popęda

Gdański Uniwersytet Medyczny, Wydział Lekarski

The clinical significance of immunosuppression in ovarian cancer microenvironments

Call: PRELUDIUM 20 , Panel: NZ6

Principal investigator: dr Anna Maria Pawłowska-Łachut

Uniwersytet Medyczny w Lublinie

Comprehensive characterization of tumor immune contexture changes induced by cytotoxic agents in non-small cell lung can...

Call: PRELUDIUM BIS 2 , Panel: NZ5

Principal investigator: prof. Wojciech Maksymilian Fendler

Uniwersytet Medyczny w Łodzi

Modulation of immune cells activity in the tumor microenvironment by oligonucleotide therapeutics delivered by silk nano...

Call: OPUS 19 , Panel: NZ6

Principal investigator: prof. Hanna Dams-Kozłowska

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Increasing the precision of chimeric antigen receptor (CAR)-mediated anticancer immunotherapy by using the chemokine-ind...

Call: OPUS 19 , Panel: NZ6

Principal investigator: dr hab. Radosław Zagożdżon

Warszawski Uniwersytet Medyczny

Photodynamic therapy combined with PD-1/PD-L1 blockade immunotherapy: new possibilities for the treatment of immunogenic...

Call: OPUS 19 , Panel: NZ7

Principal investigator: dr hab. Janusz Marcin Dąbrowski

Uniwersytet Jagielloński, Wydział Chemii

Analysis of the effectiveness of glioblastoma immunotherapy using gamma-delta T cells

Call: OPUS 18 , Panel: NZ6

Principal investigator: dr hab. Grzegorz Jacek Chodaczek

Wrocławskie Centrum Badań EIT+ Sp. z o.o.

Modulation of exosome production to support anti-cancer treatment

Call: OPUS 18 , Panel: NZ7

Principal investigator: dr Liliana Monika Czernek

Centrum Badań Molekularnych i Makromolekularnych PAN

Evaluation of the activity of MDM2-p53 antagonist RG7388 in mouse cancer models, alone and in combination with anti-PD-1...

Call: PRELUDIUM 18 , Panel: NZ5

Principal investigator: Aneta Sylwia Nieznańska

Uniwersytet Jagielloński, Wydział Chemii

The role of interferon lambda (IFN-L) in development of immunological anti-tumour mechanizm during proggression of canin...

Call: SONATA 12 , Panel: NZ5

Principal investigator: dr Joanna Milena Mucha

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Medycyny Weterynaryjnej

The role of arginase-1 in antitumor efficacy of cancer immunotherapy using checkpoint inhibitors

Call: OPUS 12 , Panel: NZ6

Principal investigator: prof. Dominika Anna Nowis

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Structural studies of signaling receptors HVEM/CD160 as potential targets for immunoterapy against melanoma

Call: SONATA 11 , Panel: NZ1

Principal investigator: dr Marta Orlikowska

Uniwersytet Gdański, Wydział Chemii

Induction of human colon cancer cells apoptosis in vitro and in vivo by Tumour Necrosis Factor-Related Apoptosis-Inducin...

Call: OPUS 8 , Panel: NZ5

Principal investigator: dr hab. Jarosław Tomasz Baran

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Analysis of immungenecity and therapeutic activity of cell cancer vaccines based on cancer stem cells and induced plurip...

Call: OPUS 4 , Panel: NZ6

Principal investigator: prof. Andrzej Mackiewicz

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski II

The expression of complement inhibitors in ovarian and corpus uteri cancers - a new perspective for immunotherapy

Call: SONATA 1 , Panel: NZ7

Principal investigator: dr hab. Lucyna Kapka-Skrzypczak

Wyższa Szkoła Informatyki i Zarządzania w Rzeszowie, Wydział Turystyki i Nauk o Zdrowiu