Projects funded by the NCN

Extracellular vesicles – potential mediators in the functioning of fish male reproductive system

Call: OPUS 29 , Panel: NZ9

Principal investigator: prof. Mariola Aleksandra Dietrich

Instytut Rozrodu Zwierząt i Badań Żywności PAN

Two pathways of the host immune response to microsporidian parasites and microsporidiosis co-infections

Call: OPUS 29 , Panel: NZ6

Principal investigator: dr hab. Aneta Agnieszka Ptaszyńska

Uniwersytet Marii Curie-Skłodowskiej w Lublinie

Effect of pesticides on gene expression, secretory function, and inflammatory response of bovine mammary epithelial cell...

Call: PRELUDIUM 24 , Panel: NZ9

Principal investigator: Justyna Para

Uniwersytet Przyrodniczy we Wrocławiu

Morphological, functional and behavioral effects of early-life immune system activation.

Call: OPUS 29 , Panel: NZ5

Principal investigator: dr hab. Joanna Małgorzata Urban-Ciećko

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Role of Regnase-1 in regulating skin immune responses during Staphylococcus aureus Infection

Call: PRELUDIUM 24 , Panel: NZ6

Principal investigator: Mariia Tyshchenko

Uniwersytet Jagielloński

Dual cell cycle blockade and immune checkpoint inhibition as a potential strategy of sequential anticancer therapy

Call: PRELUDIUM 24 , Panel: NZ7

Principal investigator: Alicja Stanisława Słota

Uniwersytet Jagielloński

LLT1 as a regulator of the immune response and a dual-target immunotherapy approach in colorectal cancer directed at NK ...

Call: OPUS 29 , Panel: NZ6

Principal investigator: dr Marzena Dorota Lenart

Uniwersytet Jagielloński

Mini-tumors, big answers: Modeling of immune system's activation with organoid-based PDT-on-Chip technology

Call: PRELUDIUM 24 , Panel: NZ7

Principal investigator: Marta Karolina Warszyńska

Uniwersytet Jagielloński

Rola TRIM32 i TRIM34 w regulacji metabolizmu guza i mikrośrodowiska immunologicznego w raku jajnika

Call: PRELUDIUM 24 , Panel: NZ6

Principal investigator: Alicja Katarzyna Rajtak

Uniwersytet Medyczny w Lublinie

Chemical synthesis, immunological evaluation and epitope analysis of carbohydrate antigens of Pseudomonas aeruginosa

Call: SHENG 4 , Panel: NZ6

Principal investigator: prof. Jolanta Katarzyna Łukasiewicz

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Novel insights into inhibition of PD-L1/PD-1 immune checkpoint – discovery and optimization of covalent PD-L1 inhibitors...

Call: SONATA 20 , Panel: ST5

Principal investigator: dr Radosław Dariusz Kitel

Uniwersytet Jagielloński

Adopted orphan nuclear receptors as new regulators of testis immune privilege

Call: SONATA 20 , Panel: NZ3

Principal investigator: dr Alicja Kinga Kamińska

Uniwersytet Jagielloński

Trichinella spiralis and Trichinella britovi multi-antigen vaccine - a new approach to prevent trichinellosis

Call: SONATA 20 , Panel: NZ6

Principal investigator: dr Anna Beata Stachyra

Warszawski Uniwersytet Medyczny

INFLOXAR - Investigation of causes of atrioventricular conduction disorders with comparison of muscle and physiological ...

Call: SONATA 20 , Panel: NZ5

Principal investigator: dr Jakub Wojciech Szyller

Politechnika Wrocławska

Impact of immune exhaustion and methylome changes on HIV reservoir across key viral subyptes

Call: OPUS 27 , Panel: NZ6

Principal investigator: prof. Miłosz Parczewski

Pomorski Uniwersytet Medyczny w Szczecinie

Immune response in ischemic stroke: T and B cells: friends or foes? A new paradigm for immune regulation

Call: PRELUDIUM 23 , Panel: NZ4

Principal investigator: Anna Mirończuk

Uniwersytet Medyczny w Białymstoku

'Trojan horse' mechanism used by Candida albicans Sap6 protease in evading neutrophil response

Call: OPUS 27 , Panel: NZ6

Principal investigator: dr Marcin Michał Zawrotniak

Uniwersytet Jagielloński

Evolution of Major Histocompatibility Complex (MHC) genes and pathogen antigens, induced by adaptive immune response and...

Call: OPUS 27 , Panel: NZ8

Principal investigator: dr Maciej Jan Ejsmond

Uniwersytet Jagielloński

Small molecule modulators of the tumor necrosis factor alpha signaling pathway for the inhibition of inflammatory proces...

Call: OPUS 27 , Panel: NZ7

Principal investigator: prof. Tadeusz Holak

Uniwersytet Gdański

Neutrophil-targeted immune response as an effective approach in immunotherapyof gastrointestinal cancers

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Damian Jacenik

Uniwersytet Łódzki

Swine dysentery - searching for early disease markers and assessing B. hyodysenteriae infection course in naïve pigs and...

Call: PRELUDIUM 23 , Panel: NZ7

Principal investigator: Agata Janina Augustyniak

Uniwersytet Przyrodniczy w Poznaniu

The role of ADP-heptose Acinetobacter baumannii in the pathogenesis of pneumonia of this etiology

Call: PRELUDIUM 23 , Panel: NZ6

Principal investigator: Karolina Justyna Sidor

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

Coating dextran nanocarriers with immune cell membranes as a way to transport active substances across the blood-brain b...

Call: PRELUDIUM 23 , Panel: ST11

Principal investigator: Daniel Filip Wyleziński

Politechnika Warszawska

Interrogation of the antigen presentation dynamics via MHCII in tumor immune evasion through multimodal single-cell sequ...

Call: SONATINA 8 , Panel: NZ2

Principal investigator: dr Natalia Ochocka-Lewicka

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Computational methods for understanding tumor immune microenvironment from spatial imaging data

Call: SONATA 19 , Panel: NZ2

Principal investigator: dr Krzysztof Kamil Gogolewski

Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

Inflammatory modes of regulated cell death in respiratory viral infections

Call: OPUS 26 , Panel: NZ6

Principal investigator: prof. Tomasz Lipniacki

Instytut Podstawowych Problemów Techniki Polska Akademia Nauk

Cross-talk between immune system and gut microbiota in Human Papillomavirus-dependentRecurrent Respiratory Papillomatosi...

Call: OPUS 26 , Panel: NZ7

Principal investigator: prof. Małgorzata Wierzbicka

Wojewódzki Szpital Specjalistyczny we Wrocławiu. Ośrodek Badawczo-Rozwojowy

Immunology of avian migrations - adaptations and constraints

Call: OPUS 26 , Panel: NZ8

Principal investigator: prof. Piotr Przemysław Minias

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Influence of environmental factors related to maternal infection during pregnancy on the development of neuropsychiatric...

Call: SONATA BIS 13 , Panel: NZ3

Principal investigator: dr Justyna Zmorzyńska

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Searching for novel regulators of antitumor immune response

Call: MAESTRO 15 , Panel: NZ6

Principal investigator: dr hab. Magdalena Hanna Winiarska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Dirofilariosis as a new zoonotic disease to control - analysis of the immune response induced by Dirofilaria repens worm

Call: PRELUDIUM 22 , Panel: NZ6

Principal investigator: Mateusz Pękacz

Uniwersytet Warszawski, Wydział Biologii

Development of dual immuno-oligo- biosensors for monitoring and controlling of the metastatic colorectal cancer and inve...

Call: OPUS 25 , Panel: ST4

Principal investigator: dr hab. Magdalena Stobiecka

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

Functional consequences of loss of chromosome Y (LOY) in immune cells in the context of cancer - ex vivo and in vitro st...

Call: OPUS 25 , Panel: NZ2

Principal investigator: dr Jan Dumański

Gdański Uniwersytet Medyczny, Międzynarodowa Agenda Badawcza

The genetic basis underlying immune resistance in selected accessions of the model plant A. thaliana against the plant p...

Call: PRELUDIUM 22 , Panel: NZ2

Principal investigator: Anastasiia Satyr

Instytut Chemii Bioorganicznej PAN

Multiparameter analysis of co-inhibitory and co-stimulatory immune checkpoints and their role in the induction of immuno...

Call: PRELUDIUM 22 , Panel: NZ6

Principal investigator: dr Dorota Suszczyk

Uniwersytet Medyczny w Lublinie

Investigating the mechanisms of epigenetic memory at the example of the responsiveness of human immune cells to vitamin ...

Call: OPUS 25 , Panel: NZ9

Principal investigator: prof. Carsten Johannes Carlberg

Instytut Rozrodu Zwierząt i Badań Żywności PAN

How Phosphorus-Containing Food Additives Affect the Gut and Metabolic Health of the Body: Having the Guts to Tackle Phos...

Call: OPUS 25 , Panel: NZ9

Principal investigator: dr hab. Adam Jurgoński

Instytut Rozrodu Zwierząt i Badań Żywności PAN

Elucidating the role of SorLA receptor in shaping immunosuppressive character of glioma microenvironment

Call: PRELUDIUM 22 , Panel: NZ4

Principal investigator: Paulina Kinga Kamińska

Uniwersytet Warszawski, Wydział Biologii

Spatial Determinants of Immunotherapy Resistance in Cancer

Call: WEAVE-UNISONO , Panel: NZ6

Principal investigator: dr Marcin Tabaka

Instytut Chemii Fizycznej Polskiej Akademii Nauk, Międzynarodowe Centrum Badań Oka

The role of genome architecture and related chromatin modifications in innate immune transcriptional memory of antigen p...

Call: Polskie Powroty NAWA 2022 , Panel: NZ2

Principal investigator: dr Paweł Sławomir Mikulski

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk - Imol

Development of novel anti-cancer immunotherapy against mesothelioma comprising of oncolytic adenovirus vectors armed wit...

Call: SONATA 18 , Panel: NZ7

Principal investigator: dr Łukasz Kuryk

Narodowy Instytut Zdrowia Publicznego - Państwowy Zakład Higieny (NIZP - PZH)

Mitigation of climate change effect on crop plants' immunity by engineering the thermostability of plant immune receptor...

Call: OPUS 24 , Panel: NZ9

Principal investigator: dr Marta Karolina Grech-Baran

Instytut Biochemii i Biofizyki PAN

Role of microparticles derived from platelets and cancer cells in colorectal cancer progression – how to stop them or tu...

Call: OPUS 24 , Panel: NZ5

Principal investigator: prof. Maria Anna Kowalska

Instytut Biologii Medycznej PAN

Specific immune signatures of T cells as biomarkers of the post-COVID Syndrome and predictors of long-term health dysfun...

Call: PRELUDIUM BIS 4 , Panel: NZ6

Principal investigator: dr hab. Katarzyna Piwocka

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Development of novel bimodal PET/MRI probes targeting PD-L1.

Call: PRELUDIUM 21 , Panel: NZ5

Principal investigator: Anna Izabela Kastelik-Hryniewiecka

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Molecular implications of gut microbiota disorders in the context of the immune system functioning in patients with prim...

Call: OPUS 23 , Panel: NZ6

Principal investigator: prof. Ewelina Pia Grywalska

Uniwersytet Medyczny w Lublinie

Molecular biomechanics of the SARS-CoV-2 variants: The virus-host cell attachment and immune evasion

Call: OPUS 23 , Panel: NZ1

Principal investigator: dr hab. Adolfo Maximo Poma Bernaola

Instytut Podstawowych Problemów Techniki Polska Akademia Nauk

Understanding multi-scale innate immune defences against bacterial pathogens at the single-cell level

Call: OPUS 23 , Panel: NZ6

Principal investigator: dr hab. Paweł Władysław Paszek

Instytut Podstawowych Problemów Techniki Polska Akademia Nauk

Use of comparative oncology approach to dissect the PD-1 intrinsic signalling in osteosarcoma. Can dog be the key for ne...

Call: PRELUDIUM 21 , Panel: NZ1

Principal investigator: Katarzyna Joanna Dziubek

Uniwersytet Gdański, Międzynarodowe Centrum Badań nad Szczepionkami Przeciwnowotworowymi

Trade-off in energy allocation between toxin production and somatic maintenance in poisonous animals

Call: OPUS 23 , Panel: NZ8

Principal investigator: dr Krzysztof Kowalski

Uniwersytet Mikołaja Kopernika, Wydział Nauk Biologicznych i Weterynaryjnych