Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Search results

74 projects found matching your search criteria :

  1. Mechanisms of MMP-3 protease involvement in plasticity of glutamatergic and GABAergic synapses: impact of MMP-3 and MMP-...

    Call: OPUS 8 , Panel: NZ4

    Principal investigator: prof. Jerzy Mozrzymas

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  2. Proteasome activation as a strategy for attenuation of aging and neurodegenerative processes

    Call: OPUS 8 , Panel: NZ7

    Principal investigator: dr hab. Elżbieta Jankowska

    Uniwersytet Gdański, Wydział Chemii

  3. "Obesity paradox" in sepsis: involvement of trinity of IL-33, neutrophil elastase and neutrophil extracellular traps (NE...

    Call: OPUS 8 , Panel: NZ6

    Principal investigator: dr hab. Elżbieta Kołaczkowska

    Uniwersytet Jagielloński, Wydział Biologii

  4. Qualitative and quantitative analyses of mycotoxins, enzymes hydrolyzing cuticle and secondary metabolites of entomopath...

    Call: SONATA 1 , Panel: NZ6

    Principal investigator: dr Monika Paszkiewicz

    Uniwersytet Gdański, Wydział Chemii

  5. Proteome, lipidome and miRN-ome of exosomes relased from head and neck cancer cells in response to genotoxic agents

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: dr hab. Monika Pietrowska

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Centrum Onkologii - Instytut im. Marii Skłodowskiej - Curie, oddział w Gliwicach

  6. The search for novel human proteasome inhibitors and fluorogenic substrates.

    Call: SONATA 1 , Panel: ST5

    Principal investigator: dr Dawid Dębowski

    Uniwersytet Gdański, Wydział Chemii

  7. Phosphonic inhibitors of human neutrophil elastase in cancer therapy

    Call: SONATA 5 , Panel: NZ4

    Principal investigator: dr Łukasz Winiarski

    Politechnika Wrocławska, Wydział Chemiczny

  8. Regulation of pre-metastatic niche for hepatic metastases of gastric cancer by portal blood proteome

    Call: OPUS 5 , Panel: NZ4

    Principal investigator: dr Marek Sierżęga

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum

  9. Unnatural amino acids as a tool for optimization of substrates architecture for targeting human cysteine protease, cathe...

    Call: PRELUDIUM 5 , Panel: ST5

    Principal investigator: dr Marcin Poręba

    Politechnika Wrocławska, Wydział Chemiczny

  10. Biochemical and physiological characterization of human protease HtrA3

    Call: OPUS 5 , Panel: NZ1

    Principal investigator: prof. Barbara Lipińska

    Uniwersytet Gdański, Wydział Biologii

  11. Susceptibility of human antimicrobial peptides to the action of aspartic proteases secreted by pathogenic yeast Candida ...

    Call: PRELUDIUM 5 , Panel: NZ1

    Principal investigator: Oliwia Bocheńska

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  12. Extracellular proteolytic activity of human epithelium - role in the modulation of signal transduction.

    Call: SYMFONIA 1 , Panel: NZ1

    Principal investigator: prof. Jan Potempa

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  13. Effect of deimination of essential arginine residues on the function of protease inhibitors and other components of inna...

    Call: OPUS 3 , Panel: NZ6

    Principal investigator: dr Tomasz Kantyka

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  14. Identification of serum proteome components associated with risk of early metastasis of breast cancer

    Call: PRELUDIUM 3 , Panel: NZ4

    Principal investigator: dr Anna Walaszczyk

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie Oddział w Gliwicach, Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

  15. Comparative proteomic analysis of the consecutive developmental stages (oncosphere, cysticercoid, adult) of the model ce...

    Call: OPUS 3 , Panel: NZ6

    Principal investigator: dr hab. Daniel Młocicki

    Instytut Parazytologii im. Witolda Stefańskiego PAN

  16. Nuclear protein quality control in neurodegeneration

    Call: SONATA 19 , Panel: NZ3

    Principal investigator: dr Lidia Wróbel

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

  17. Protease-induced neutrophilic networks in cancer development.

    Call: SONATA 19 , Panel: NZ5

    Principal investigator: dr Danuta Bryzek

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  18. PROteolysis TArgeting Chimeras (PROTACs) intended to knock down excessive amyloidogenic proteins, human islet amyloid po...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr hab. Elżbieta Jankowska

    Uniwersytet Gdański, Wydział Chemii

  19. The role of extracytoplasmic proteases in the physiology and morphology of the bacterium Helicobacter pylori

    Call: SONATA 19 , Panel: NZ2

    Principal investigator: dr Urszula Zarzecka

    Uniwersytet Gdański, Wydział Biologii

  20. Macrocyclic peptides for targeting of membrane-anchored serine protease

    Call: PRELUDIUM BIS 5 , Panel: NZ7

    Principal investigator: dr hab. Paulina Kasperkiewicz-Wasilewska

    Politechnika Wrocławska

  21. Dissecting the regulatory interplay between proteases and protein kinases in acute lymphoblastic leukemia using mass cyt...

    Call: OPUS 24 , Panel: NZ5

    Principal investigator: dr hab. Marcin Poręba

    Politechnika Wrocławska

  22. Mitochondrial stress induced proteasome

    Call: SONATA 18 , Panel: NZ5

    Principal investigator: dr Agata Kodroń

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  23. Role of neutrophil serine proteases in chronic inflammatory skin diseases associated with Regnase-1 malfunction

    Call: OPUS 23 , Panel: NZ6

    Principal investigator: prof. Joanna Cichy

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  24. Epigenetic traces of anhydrobiosis: a study of DNA and protein modifications through tardigrade generations

    Call: PRELUDIUM BIS 3 , Panel: NZ4

    Principal investigator: dr hab. Robert Nawrot

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  25. Evaluation of the brain microbiome and proteome as well as the role of fecal microbiota transplantation (FMT) in schizop...

    Call: SONATA 17 , Panel: NZ5

    Principal investigator: dr Dominika Salamon

    Uniwersytet Jagielloński, Collegium Medicum

  26. The structures, biochemistry, physiology, and evolution of bacterial α2-macroglobulins from the human periodontopathogen...

    Call: SONATA BIS 11 , Panel: NZ1

    Principal investigator: dr Mirosław Książek

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  27. Mechanism of biofilm formation by uropatogenic E. coli producing fimbrial adhesin Dr - studies of proteome and metabolom...

    Call: OPUS 21 , Panel: NZ6

    Principal investigator: dr hab. Rafał Piątek

    Politechnika Gdańska, Wydział Chemiczny

  28. Role of GAB glutaminase in glioblastoma.

    Call: OPUS 21 , Panel: NZ5

    Principal investigator: dr hab. Monika Szeliga

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  29. Hybrid human SUMO proteins for selective detection and labelling of SENP proteases

    Call: OPUS 21 , Panel: ST4

    Principal investigator: dr Wioletta Rut

    Politechnika Wrocławska

  30. The role of neutrophil serine proteases in the regulation of function of the podocyte and glomerular filtration barrier.

    Call: OPUS 21 , Panel: NZ4

    Principal investigator: dr hab. Agnieszka Piwkowska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  31. Mechanisms of host-pathogen interaction in the immune response of Galleria mellonella after infection with entomopathoge...

    Call: OPUS 1 , Panel: NZ6

    Principal investigator: dr hab. Iwona Wojda

    Uniwersytet Marii Curie-Skłodowskiej, Wydział Biologii i Biotechnologii

  32. The role of extracellular proteases – yapsins – in gaining pathogenic advantage by Candida glabrata in the host organism...

    Call: SONATA 16 , Panel: NZ6

    Principal investigator: dr Dorota Satała

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  33. Dissecting cancer activome to develop new generation of antibody-drug conjugates

    Call: OPUS 20 (LAP) , Panel: NZ5

    Principal investigator: dr hab. Marcin Poręba

    Politechnika Wrocławska

  34. Cooperation between the extracytoplasmic protein quality control system and the Sec translocon in the process of protein...

    Call: OPUS 20 , Panel: NZ2

    Principal investigator: prof. Joanna Skórko-Glonek

    Uniwersytet Gdański, Wydział Biologii

  35. Defining the interplay between SLPI and the IL-1 family cytokines in the immune response

    Call: SONATA 16 , Panel: NZ6

    Principal investigator: dr Ewa Oleszycka

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  36. Molecular mechanism underlying the anti-inflammatory action of CB2 receptor agonists in microglia: participation of the ...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: dr Natalia Małek-Chudzik

    Politechnika Wrocławska

  37. Metabolomic and proteomic studies combined with modern magnetic resonance imaging techniques to explore mechanisms of br...

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: prof. Przemko Kwinta

    Uniwersytet Jagielloński, Collegium Medicum

  38. Host sex effect on immunity and protection after oral immunization with Fasciola hepatica cysteine protease and the para...

    Call: OPUS 18 , Panel: NZ6

    Principal investigator: dr hab. Małgorzata Kęsik-Brodacka

    Sieć Badawcza ŁUKASIEWICZ - Instytut Biotechnologii i Antybiotyków

  39. Novel analogs of human cathelicidin (LL-37) with enhanced resistant to enzymatic degradation. Design chemical synthesis ...

    Call: PRELUDIUM BIS 1 , Panel: ST4

    Principal investigator: prof. Adam Lesner

    Uniwersytet Gdański, Wydział Chemii

  40. Molecular mechanisms modulating the function of UCH-L1 deubiquitinase in human mitochondria

    Call: OPUS 18 , Panel: NZ3

    Principal investigator: prof. Agnieszka Chacińska

    Fundacja ReMedy+

  41. The KLIKK proteases of human pathogen Tannerella forsythia: putative virulence factors with unique biochemical and struc...

    Call: OPUS 18 , Panel: NZ1

    Principal investigator: dr Mirosław Książek

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  42. SufA bacterial protease inhibitors as potential diagnostic tools and antibacterial agents.

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Ewa Burchacka

    Politechnika Wrocławska

  43. Hijacking the ubiquitin-proteasome system by the UL49.5 protein of bovine herpesvirus 1 as an immune evasion strategy – ...

    Call: PRELUDIUM 18 , Panel: NZ6

    Principal investigator: Magda Wąchalska

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  44. Inhibitors of serine proteases as regulators of dendritic cell function.

    Call: MAESTRO 1 , Panel: NZ5

    Principal investigator: prof. Joanna Cichy

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  45. Design and synthesis of proteolytically stable and cell permeable activators of human 20S proteasome and assessing their...

    Call: PRELUDIUM BIS 1 , Panel: NZ7

    Principal investigator: dr hab. Elżbieta Jankowska

    Uniwersytet Gdański, Wydział Chemii

  46. Preventing the accumulation of cytotoxic oligomers, that are causative agents of neurodegenerative diseases and Type 2 D...

    Call: OPUS 17 , Panel: NZ7

    Principal investigator: dr hab. Elżbieta Jankowska

    Uniwersytet Gdański, Wydział Chemii

  47. Effects of proteasome inhibition on mitochondrial homeostasis.

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: prof. Agnieszka Chacińska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  48. Multi-level molecular assessment based on laser microdissection of corneas to reveal biomarkers and therapeutic targets ...

    Call: OPUS 16 , Panel: NZ5

    Principal investigator: prof. Marzena Gajęcka

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  49. Characterization of two novel proteases from the human periodontopathogen Tannerella forsythia

    Call: PRELUDIUM 16 , Panel: NZ1

    Principal investigator: Irena Waligórska

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  50. Dissecting the proteolytic fingerprint of breast cancer tissues using mass cytometry for personalized oncology.

    Call: SONATA 14 , Panel: NZ5

    Principal investigator: dr Marcin Poręba

    Politechnika Wrocławska