Projects funded by the NCN

Identification and structural characterization of the primordial cytotoxic conformers of the amyloidogenic cascade: Idea...

Call: UNISONO , Panel: NZ1

Principal investigator: prof. Marek Cieplak

Instytut Fizyki PAN

Silver(I) complexes of imidazole and pyridine derivatives - synthesis, structural characterization, antimicrobial and cy...

Call: OPUS 8 , Panel: NZ7

Principal investigator: prof. Justyn Ochocki

Uniwersytet Medyczny w Łodzi, Katedra Chemii Medycznej, Zakład Chemii Bionieorganizcnej

Synthesis, structural and cytotoxic in vitro studies of new ruthenium complexes with modified purine ligands

Call: PRELUDIUM 1 , Panel: ST5

Principal investigator: Marzena Fandzloch

UNIWERSYTET MIKOŁAJA KOPERNIKA W TORUNIU, Wydział Chemii

An examination of the impact of saponins on Langmuir monolayers as model lipid membranes.

Call: PRELUDIUM 7 , Panel: ST4

Principal investigator: Marta Orczyk

Politechnika Warszawska, Wydział Chemiczny

Proapoptotic activity of dried leaf blade aqueouos extract from Vilcacora (Uncaria tomentosa) in selected cancer cell li...

Call: PRELUDIUM 5 , Panel: NZ7

Principal investigator: Anita Kośmider

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Structure and functions of the cell cytoskeleton during development of germ-line cysts in the earthworm Dendrobaena vene...

Call: PRELUDIUM 4 , Panel: NZ4

Principal investigator: Karol Małota

Uniwersytet Śląski w Katowicach, Wydział Biologii i Ochrony Środowiska

Influence of dicarboxylate on in vitro cytotoxic properties of platinum(II) coordination compounds with substituted tria...

Call: PRELUDIUM 4 , Panel: ST5

Principal investigator: Kamil Hoffmann

Uniwersytet Mikołaja Kopernika, Wydział Chemii

The examination of isothiocyanates influence on cytotoxic and cytostatic effects of 5-fluorouracil in cancer cell lines ...

Call: PRELUDIUM 3 , Panel: NZ5

Principal investigator: Małgorzata Milczarek

Narodowy Instytut Leków

Search for compounds of anticancer activity in the group of polyphenolbenothiazinones and their derivatives

Call: OPUS 1 , Panel: NZ4

Principal investigator: prof. Joanna Matysiak

Uniwersytet Przyrodniczy w Lublinie, Wydział Nauk o Żywności i Biotechnologii

Research on the pharmacological properties of compounds from the Greater Celenadine's (Chelidonium majus L.) milky sap a...

Call: OPUS 2 , Panel: NZ9

Principal investigator: dr Robert Nawrot

UNIWERSYTET IM.A.MICKIEWICZA W POZNANIU

New insight into the mechanism of cytotoxic brain edema in acute liver failure: focus on the functionality of mitochondr...

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Mariusz Popek

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

Highly-internalizing intrinsically fluorescent oligomeric cytotoxic conjugate targeting breast cancer cells overproducin...

Call: PRELUDIUM 21 , Panel: NZ1

Principal investigator: dr Natalia Porębska

Uniwersytet Wrocławski, Wydział Biotechnologii

Identification of anticancer phytochemicals of dandelion root (Taraxaci radix) based on metabolomics and bioassay-guided...

Call: PRELUDIUM 21 , Panel: NZ9

Principal investigator: Sylwia Pawelec

Instytut Uprawy Nawożenia i Gleboznawstwa - Państwowy Instytut Badawczy

Targeting cell surface proteoglycans with high affinity multimeric ligands and their cytotoxic conjugates – towards prec...

Call: OPUS 22 , Panel: NZ1

Principal investigator: dr hab. Łukasz Opaliński

Uniwersytet Wrocławski, Wydział Biotechnologii

Analysis of semaphorin 3 (SEMA3), protocadherin 9 (PCDH9) and S 100 calcium binding proteinA3 (S100A3) expression in pro...

Call: OPUS 21 , Panel: NZ5

Principal investigator: dr hab. Radosław Januchowski

Uniwersytet Zielonogórski, Collegium Medicum

The study on the molecular mechanisms of cytotoxic activity of new compounds ZOT5-1-Me and ZOT5-1-Et in an experimental ...

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr Paulina Tokarz

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Comprehensive characterization of tumor immune contexture changes induced by cytotoxic agents in non-small cell lung can...

Call: PRELUDIUM BIS 2 , Panel: NZ5

Principal investigator: prof. Wojciech Fendler

Uniwersytet Medyczny w Łodzi

The role of airway interferon response and its impact on the activation of immune system in antisynthetase syndrome

Call: PRELUDIUM 19 , Panel: NZ6

Principal investigator: Aleksandra Opinc

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Understanding the molecular mechanism of toxic action of the most dangerous trichothecene - T-2 toxin

Call: PRELUDIUM 19 , Panel: NZ9

Principal investigator: Edyta Janik

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Cytotoxic conjugates targeting FGFR-related cancers based on FGF1 and FGFR-specific antibodies.

Call: MAESTRO 1 , Panel: NZ1

Principal investigator: prof. Jacek Otlewski

Uniwersytet Wrocławski, Wydział Biotechnologii

Chemical architecture of fluorinated nucleoside dimers containing 1,2,3-triazole linker of potential use in molecular bi...

Call: SONATA 15 , Panel: NZ7

Principal investigator: dr Dagmara Baraniak

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Preventing the accumulation of cytotoxic oligomers, that are causative agents of neurodegenerative diseases and Type 2 D...

Call: OPUS 17 , Panel: NZ7

Principal investigator: dr hab. Elżbieta Jankowska

Uniwersytet Gdański, Wydział Chemii

Determination of potential application of glutathione-coated silver nanoparticles in periodontal disease prevention by c...

Call: PRELUDIUM 14 , Panel: NZ7

Principal investigator: dr Ewelina Barcińska

Gdański Uniwersytet Medyczny, Wydział Lekarski

Modification of the DNA helix structure by newly synthesized cytotoxic compound (Cl-IPBD) in selected cancer cell lines ...

Call: PRELUDIUM 13 , Panel: NZ7

Principal investigator: dr Dominika Janiszek

Uniwersytet Warszawski, Wydział Chemii

Modifications of betulin A ring in the synthesis of cytotoxic derivatives.

Call: OPUS 11 , Panel: ST5

Principal investigator: dr hab. Zbigniew Pakulski

Instytut Chemii Organicznej Polskiej Akademii Nauk

New materials in form of nanocrystallline thin films based on titanium with various copper content, of controlled antiba...

Call: OPUS 11 , Panel: ST8

Principal investigator: dr hab. Bogumiła Szponar

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Secondary metabolites from fruit, leaves, and twigs of sea buckthorn (Hippophae rhamnoides L.) as natural bioactive subs...

Call: OPUS 10 , Panel: NZ9

Principal investigator: prof. Anna Stochmal

Instytut Uprawy Nawożenia i Gleboznawstwa - Państwowy Instytut Badawczy

Cytotoxic folic acid analogues and breaking through the multidrug resistance barrier

Call: OPUS 9 , Panel: NZ7

Principal investigator: dr Błażej Rychlik

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska