Projects funded by the NCN

Strategy to overcome the "ionic checkpoint" and improve the antitumor immunotherapy.

Call: OPUS 29 , Panel: NZ7

Principal investigator: dr Beata Pyrzyńska

Warszawski Uniwersytet Medyczny

Dual cell cycle blockade and immune checkpoint inhibition as a potential strategy of sequential anticancer therapy

Call: PRELUDIUM 24 , Panel: NZ7

Principal investigator: Alicja Stanisława Słota

Uniwersytet Jagielloński

Novel insights into inhibition of PD-L1/PD-1 immune checkpoint – discovery and optimization of covalent PD-L1 inhibitors...

Call: SONATA 20 , Panel: ST5

Principal investigator: dr Radosław Dariusz Kitel

Uniwersytet Jagielloński

Development of novel anti-cancer immunotherapy against mesothelioma comprising of oncolytic adenovirus vectors armed wit...

Call: SONATA 18 , Panel: NZ7

Principal investigator: dr Łukasz Kuryk

Narodowy Instytut Zdrowia Publicznego - Państwowy Zakład Higieny (NIZP - PZH)

Role of microparticles derived from platelets and cancer cells in colorectal cancer progression – how to stop them or tu...

Call: OPUS 24 , Panel: NZ5

Principal investigator: prof. Maria Anna Kowalska

Instytut Biologii Medycznej PAN

Use of comparative oncology approach to dissect the PD-1 intrinsic signalling in osteosarcoma. Can dog be the key for ne...

Call: PRELUDIUM 21 , Panel: NZ1

Principal investigator: Katarzyna Joanna Dziubek

Uniwersytet Gdański, Międzynarodowe Centrum Badań nad Szczepionkami Przeciwnowotworowymi

Impact of the CDK4/6 targeted degradation by PROTACs on immune checkpoint signaling in cancer

Call: OPUS 22 , Panel: NZ7

Principal investigator: dr Katarzyna Magiera-Mularz

Uniwersytet Jagielloński, Wydział Chemii

Photoswitchable and chimeric molecules for spatially restricted and endoplasmic reticulum-specific blockade of PD-L1 pro...

Call: SONATA BIS 11 , Panel: NZ7

Principal investigator: dr Łukasz Dariusz Skalniak

Uniwersytet Jagielloński, Wydział Chemii

Novel factors involved in cell cycle control after DNA damage.

Call: OPUS 21 , Panel: NZ1

Principal investigator: dr Michał Zbigniew Malewicz

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

The SAR analysis and synthesis of complex, small molecule PD-1/PD-L1 interaction antagonists

Call: PRELUDIUM 20 , Panel: ST4

Principal investigator: Magdalena Maria Żarnik

Uniwersytet Jagielloński, Wydział Chemii

Single cell multi-omics in defining how specific oncogenic alterations shape the immune microenvironment and responses t...

Call: OPUS 20 , Panel: NZ4

Principal investigator: prof. Bożena Kamińska-Kaczmarek

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Evaluation of the anticancer efficacy of a new chimeric antigen receptor targeting PD-L1 molecule

Call: OPUS 12 , Panel: NZ6

Principal investigator: dr hab. Radosław Zagożdżon

Warszawski Uniwersytet Medyczny, Wydział Lekarski

The role of arginase-1 in antitumor efficacy of cancer immunotherapy using checkpoint inhibitors

Call: OPUS 12 , Panel: NZ6

Principal investigator: prof. Dominika Anna Nowis

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Identification of Saccharomyces cerevisiae genes maintaining cell diploidy and genome stability

Call: OPUS 2 , Panel: NZ2

Principal investigator: dr hab. Adrianna Martyna Skoneczna

Instytut Biochemii i Biofizyki PAN

Evaluation of the efficiency of Spindle Assembly Checkpoint during mouse oocyte meiosis

Call: OPUS 1 , Panel: NZ3

Principal investigator: dr hab. Zbigniew Piotr Polański

Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi