Projects funded by the NCN

Expression of selenoproteins and NRF2-modulated genes in bladder cancer ethiology and disease process

Call: OPUS 3 , Panel: NZ5

Principal investigator: dr hab. Edyta Wiesława Reszka

INSTYTUT MEDYCYNY PRACY IM.PROF.DR MED.JERZEGO NOFERA W ŁODZI

Study of the effect of 17-beta estradiol on expression of gene encoding hypoxia inducible factor - 1 alpha (HIF-1 alpha)...

Call: PRELUDIUM 3 , Panel: NZ5

Principal investigator: dr Agnieszka Anna Rawłuszko-Wieczorek

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski I

Follicular thyroid cancer somatic mutations profiling with massively parallel sequencing method. Sanger and next-generat...

Call: PRELUDIUM 2 , Panel: NZ5

Principal investigator: dr Bartosz Stefan Wojtaś

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Activity evaluation of procaryotic TA modules in a dual-component model of cancer therapy

Call: PRELUDIUM 2 , Panel: NZ5

Principal investigator: Łukasz Janusz Wieteska

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu; Zakład Biochemii Medycznej

Developing histone deacetylase-inhibiting hybrid analogs of pleurocidin and their potential in the treatment of HPV-indu...

Call: SONATA 20 , Panel: NZ7

Principal investigator: dr hab. Ewelina Piktel

Uniwersytet Medyczny w Białymstoku

Environmental modulation of CDK4/6 inhibitor efficacy: Impact of mycotoxin alternariol exposure on anti-cancer therapies

Call: SONATA 20 , Panel: NZ5

Principal investigator: dr Anna Dominika Walczak-Szeffer

Uniwersytet Medyczny w Łodzi

Analysis of the effects of proteotoxic stress on cholesterol homeostasis and its associations with cardiovascular diseas...

Call: OPUS 28 , Panel: NZ5

Principal investigator: prof. Wiesława Elżbieta Widłak

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Quad-TNT: Quadruplex-Targeted Photo-Therapy for Triple-Negative Tumors

Call: SONATA BIS 14 , Panel: NZ5

Principal investigator: dr Marco Deiana

Politechnika Wrocławska

Molecular factors and pathomechanism of cancer-associated cachexia.

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr hab. Marcin Tomasz Skrzypski

Gdański Uniwersytet Medyczny

ERβ-mediated autophagy in colorectal cancer and its impact on carcinogenesis

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Julia Maria Lipowicz

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Profiling of the stroma by spatial transcriptomics in aid of prognostication in FGFR2-mediated luminal breast cancer

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Julia Maria Sołek-Siejka

Uniwersytet Medyczny w Łodzi

Precision double strike against non-small cell lung cancer. Insights into multidirectional therapies and the landscape o...

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Katarzyna Anna Malarz

Politechnika Śląska

Neutrophil-targeted immune response as an effective approach in immunotherapyof gastrointestinal cancers

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Damian Jacenik

Uniwersytet Łódzki

Evaluation of the relationship between doxorubicin resistance, epithelial-mesenchymal plasticity, and effects of selecte...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Dominika Kunachowicz

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Proteomic predictors of metastasis in colorectal cancer – a validation study

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr hab. Anna Wojakowska

Instytut Chemii Bioorganicznej PAN

The Prognostic Utility of Circulating Tumor Cells (CTCs) Derived from the Portal Vein in Operable Colorectal Cancer Pati...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Claudia Dompé

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Cellular senescence as a new mechanism in development and progression of head and neck cancer

Call: OPUS 26 , Panel: NZ5

Principal investigator: prof. Michał Mateusz Masternak

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Defining the transcriptional and epigenetic state of tumor cells with increased plasticity and the epithelial-endothelia...

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr hab. Agnieszka Kobielak

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

In search for DNA methylation aberrations associated with susceptibility to ovarian cancer

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr Malwina Magdalena Suszyńska

Instytut Chemii Bioorganicznej PAN

To be or not to be modified: the role of single m6A sites of long noncoding RNAs in breast cancer

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Elżbieta Wanowska

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

The role of oxidative stress, inflammation, disorders of purine metabolism, urea cycle and angiogenesis at the molecular...

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Paulina Wigner-Jeziorska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Protease-induced neutrophilic networks in cancer development.

Call: SONATA 19 , Panel: NZ5

Principal investigator: dr Danuta Teresa Bryzek

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Targeting adenylate kinase 4 (AK4) as a new paradigm in the treatment of non-small cell lung cancer: discovery and evalu...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr Magdalena Wujak

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

Novel aspects of the mechanisms of vascular toxicity of tyrosine kinase inhibitors: studies on their proinflammatory act...

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr Tomasz Krzysztof Prajsnar

Uniwersytet Jagielloński, Wydział Biologii

Increasing sensitivity to immunotherapy in lung cancer via immunostimulation and modulation of tumor microenvironment

Call: SONATA BIS 13 , Panel: NZ5

Principal investigator: dr Urszula Oleksiewicz

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Extensive analysis of the immunological profile of pediatric patients with acute lymphoblastic leukemia in order to iden...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Anna Krętowska-Grunwald

Uniwersytet Medyczny w Białymstoku

The mechanism of competition of mutant p53 gain-of-function and major oncogene CMYC in gastric cancer.

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Marcin Mikołaj Grochowski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Anticancer potential of TMPyP4 porphyrin in breast cancer photodynamic therapy and evaluation of the treatment safety

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Błażej Rubiś

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Predictive Potential of Circulating MicroRNA Biomarkers in Patients with High Familial or Genetic Risk of Cancer

Call: OPUS 25 , Panel: NZ5

Principal investigator: prof. Wojciech Fendler

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Chiral hybrids of quinones and quinols with double anticancer and antimicrobial activity against drug-resistant pathogen...

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Ryszard Józef Ostaszewski

Instytut Chemii Organicznej Polska Akademia Nauk

Investigating the anti-cancerous effect of antioxidant extract from spent coffee grounds on the functioning of normal an...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Adrianna Maria Piasek

Politechnika Warszawska, Wydział Chemiczny

The study of the effect of hypoxia on the metabolism of exogenous ferritin and its role in the regulation of free iron i...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: dr Małgorzata Maria Kubiak

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Centrum Immunoterapii Komórkowych

Determining the frequency of occurrence and defining the most appropriate screening test for anal intraepithelial neopla...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Michał Zygmunt Brzeziński

Gdański Uniwersytet Medyczny, Wydział Nauk o Zdrowiu z Instytutem Medycyny Morskiej i Tropikalnej, Zakład Propedeutyki Onkologii

Assessing ovarian cancer molecular heterogeneity by NMR-based metabolomics, spatially resolved transcriptomics and metab...

Call: OPUS 25 , Panel: NZ5

Principal investigator: prof. Maria Bożena Sokół

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Ultrasensitive profiling of mutations driving tumorigenesis in hereditary syndromes associated with tumor suppressor gen...

Call: OPUS 25 , Panel: NZ5

Principal investigator: dr Katarzyna Klonowska

Instytut Chemii Bioorganicznej PAN

Investigating the mechanisms of epithelial/mesenchymal plasticity and metastasis.

Call: OPUS 25 , Panel: NZ5

Principal investigator: dr Anna Agnieszka Marusiak

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Dissecting the regulatory interplay between proteases and protein kinases in acute lymphoblastic leukemia using mass cyt...

Call: OPUS 24 , Panel: NZ5

Principal investigator: dr hab. Marcin Łukasz Poręba

Politechnika Wrocławska

Determination of the SNAIL1 transcription factor effect on biology cancer stem cells in rhabdomyosarcoma model

Call: OPUS 24 , Panel: NZ5

Principal investigator: prof. Marcin Marek Majka

Uniwersytet Jagielloński, Collegium Medicum

Identifying angiogenic and metabolic biomarkers in endometriosis-associated ovarian cancer using photoacoustic imaging a...

Call: POLONEZ BIS 3 , Panel: NZ5

Principal investigator: dr Monika Anna Golińska

Uniwersytet Medyczny w Łodzi

Precise molecular characterization of circulating tumour cells in patients with triple negative breast cancer using high...

Call: OPUS 24 , Panel: NZ7

Principal investigator: prof. Stefano Volinia

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Role of microparticles derived from platelets and cancer cells in colorectal cancer progression – how to stop them or tu...

Call: OPUS 24 , Panel: NZ5

Principal investigator: prof. Maria Anna Kowalska

Instytut Biologii Medycznej PAN

Molecular insights into hypoxic tumors – for development of targeted cancer therapeutics

Call: POLONEZ BIS 3 , Panel: NZ5

Principal investigator: dr Marco Deiana

Politechnika Wrocławska

Oncogene competition - a new interplay mechanism of mutant p53 with CMYC and mutant KRAS in human cancers.

Call: OPUS 23 , Panel: NZ5

Principal investigator: dr hab. Dawid Włodzimierz Walerych

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Role of the PARP1/HPF1 complex in the conferring of resistance to doxorubicin in triple negative breast cancer

Call: PRELUDIUM 21 , Panel: NZ5

Principal investigator: Magdalena Alicja Strachowska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Histone demethylase inhibitors as chemosensitivity modulators in the treatment of head and neck squamous cell carcinoma

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Dawid Dariusz Dorna

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Pancreatic cancer oxygenation as a prognostic marker during anticancer therapy

Call: OPUS 23 , Panel: NZ5

Principal investigator: dr Martyna Krzykawska-Serda

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Intrinsic tumour radiosensitivity as a marker of chemoradiotherapy-induced immunogenic effects in rectal cancer

Call: PRELUDIUM 21 , Panel: NZ5

Principal investigator: Zuzanna Maria Nowicka

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

The role of MTARC2 protein-related metabolism changes in the intestinal tumorigenesis

Call: OPUS 23 , Panel: NZ5

Principal investigator: dr hab. Michał Marek Mikula

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Local and systemic Tryptophan metabolites as gastric cancer biomarkers

Call: PRELUDIUM 21 , Panel: NZ5

Principal investigator: Kinga Ożga

Katolicki Uniwersytet Lubelski Jana Pawła II

MicroRNA expression as a dissemination factor in colon cancer stage pT2-4N0

Call: OPUS 2 , Panel: NZ5

Principal investigator: dr Marcin Skrzypski

Gdański Uniwersytet Medyczny, Wydział Lekarski