Projects funded by the NCN

Targeting the NS3 protease of neglected yellow fever-related Orthoflaviviruses

Call: OPUS 28 (LAP) , Panel: NZ6

Principal investigator: dr hab. Paulina Maria Kasperkiewicz-Wasilewska

Politechnika Wrocławska

Development of One-pot Multienzymatic Cascade Systems for Sustainable Synthesis of Active Pharmaceutical Ingredients

Call: SONATA BIS 14 , Panel: ST8

Principal investigator: dr hab. Jakub Łukasz Zdarta

Politechnika Poznańska

Development of new antibacterial agents based on lytic enzymes produced by bacteriophages

Call: SONATA BIS 13 , Panel: NZ1

Principal investigator: dr Monika Wojciechowska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Plasmonic nanoparticles decorated with fluorescently-labelled mRNA: using single-pair FRET effect for investigating enzy...

Call: OPUS 25 , Panel: ST4

Principal investigator: prof. Joanna Niedziółka-Jönsson

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Optimization of coarse-grained molecular dynamics simulations for tunnel exploration of large proteins with buried activ...

Call: PRELUDIUM 22 , Panel: NZ2

Principal investigator: Nishita Mandal

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Synthesis of active pharmaceutical ingredients with the use of biocatalysts supported by ionic liquids

Call: PRELUDIUM 22 , Panel: ST8

Principal investigator: Oliwia Degórska

Politechnika Poznańska, Wydział Technologii Chemicznej

The Power of Hybrid – Development of Novel Multienzymatic Cascade Reactions and Photo-Biocatalytic Redox Systems for Asy...

Call: OPUS 24 , Panel: ST4

Principal investigator: dr Paweł Borowiecki

Politechnika Warszawska

Mechanisms of cyclization reactions leading to biologically active compounds catalyzed by iron dependent enzymes.

Call: OPUS 23 , Panel: ST4

Principal investigator: prof. Tomasz Maciej Borowski

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Combined experimental and theoretical studies of the catalytic activity of RPE65 enzyme using biomimetic active centre m...

Call: OPUS 20 , Panel: ST4

Principal investigator: dr hab. Adam Maciej Kubas

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Molecular origins of mechanisms governing biological functions of enzymes with buried actives sites: substrate inhibitio...

Call: SONATA BIS 7 , Panel: NZ1

Principal investigator: dr hab. Jan Brezovsky

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Structure and function of anti-virulent phage origin enzymes active against ESKAPE pathogens

Call: HARMONIA 9 , Panel: NZ1

Principal investigator: prof. Zuzanna Drulis-Kawa

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

2-Oxoglutarate dependent oxygenases in the biosynthesis of pharmacologically active alkaloids - structure, catalytic mec...

Call: SONATA BIS 4 , Panel: NZ1

Principal investigator: prof. Tomasz Maciej Borowski

Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

Selective activity based probes for imaging of active serine proteases in neutrophils.

Call: HARMONIA 6 , Panel: ST5

Principal investigator: dr hab. Marcin Drąg

Politechnika Wrocławska, Wydział Chemiczny

Morita-Baylis-Hillman adducts as substrates in the synthesis of biologically active organophosphorus compounds

Call: OPUS 5 , Panel: ST5

Principal investigator: dr hab. Artur Jacek Mucha

Politechnika Wrocławska, Wydział Chemiczny

The use of proteolytic enzymes isolated form nonconventional sources for obtaining biologically active peptides from mil...

Call: OPUS 1 , Panel: NZ9

Principal investigator: dr Anna Ewa Dąbrowska

Uniwersytet Przyrodniczy we Wrocławiu, Wydział Nauk o Żywności