Projects funded by the NCN

Aromatic aminotransferases from Candida albicans as molecular targets for antifungal chemotherapy.

Call: OPUS 9 , Panel: NZ6

Principal investigator: dr Iwona Gabriel

Politechnika Gdańska, Wydział Chemiczny

Introduction to the Aramaic Bible

Call: OPUS 8 , Panel: HS1

Principal investigator: prof. Mirosław Wróbel

Katolicki Uniwersytet Lubelski Jana Pawła II, Wydział Teologii

Identification and structural characterization of the primordial cytotoxic conformers of the amyloidogenic cascade: Idea...

Call: UNISONO , Panel: NZ1

Principal investigator: prof. Marek Cieplak

Instytut Fizyki PAN

DNA repair pathways contributing to resistance to photodynamic therapy and as possible theraupeutic targets

Call: OPUS 8 , Panel: NZ5

Principal investigator: dr hab. Elżbieta Speina

Instytut Biochemii i Biofizyki PAN

Upstream regulators and cellular targets of the selective autophagy cargo receptor AtNBR1 in different phases of sulfur ...

Call: OPUS 8 , Panel: NZ3

Principal investigator: prof. Agnieszka Sirko

Instytut Biochemii i Biofizyki PAN

The role of bioactive sphingolipids: ceramide, ceramide-1-phosphate and sphingosine-1-phosphate in regulation of mitocho...

Call: OPUS 8 , Panel: NZ3

Principal investigator: dr hab. Robert Strosznajder

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Approach to structures of difficult protein targets using new mass spectrometry-based methods

Call: MAESTRO 6 , Panel: NZ1

Principal investigator: prof. Michał Dadlez

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Design and synthesis of probes for RabGGTase profiling and their application for identification of the site of phosphono...

Call: SONATA BIS 4 , Panel: ST5

Principal investigator: dr hab. Katarzyna Błażewska

Politechnika Łódzka, Wydział Chemiczny

Identification and functional analysis of nitric oxide-dependent metabolic targets in Phytophthora infestans (Mont.) de ...

Call: OPUS 7 , Panel: NZ9

Principal investigator: dr hab. Magdalena Arasimowicz-Jelonek

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Analysis of relations on the level of metabolome, miRNome, and transcriptome of human renal cancer: towards identificati...

Call: OPUS 7 , Panel: NZ5

Principal investigator: dr hab. Agnieszka Piekiełko-Witkowska

Centrum Medyczne Kształcenia Podyplomowego

Legal targets in armed conflicts from states' and non-state actors' perspective

Call: SONATA 6 , Panel: HS5

Principal investigator: dr Patrycja Grzebyk

Uniwersytet Warszawski, Wydział Nauk Politycznych i Studiów Międzynarodowych

The role of sphingosine-1-phosphate (S1P) receptors signaling in animal model of Parkinson disease. Searching of novel t...

Call: PRELUDIUM 5 , Panel: NZ4

Principal investigator: Joanna Motyl

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

The role of poly(ADP-ribose) polymerase and sirtuins in molecular mechanism of cell death. Identification of novel targe...

Call: OPUS 5 , Panel: NZ3

Principal investigator: prof. Joanna Strosznajder

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Characteristics of the cell wall hydrolases of pathogenic bacteria Listeria monocytogenes and their partcipation in the ...

Call: OPUS 5 , Panel: NZ6

Principal investigator: dr hab. Magdalena Popowska

Uniwersytet Warszawski, Wydział Biologii

High throughput determination of RNA targets for MBNL1 splicing factor - Implication for myotonic dystrophy

Call: OPUS 1 , Panel: NZ1

Principal investigator: dr hab. Krzysztof Sobczak

Uniwersytet im. Adama Mickiewicza, Wydział Biologii

Application of reporter cell biosensors in ecotoxicology of cyanobacteria: new targets for bioactivity

Call: OPUS 4 , Panel: NZ8

Principal investigator: prof. Joanna Mankiewicz-Boczek

Europejskie Regionalne Centrum Ekohydrologii Polskiej Akademii Nauk

Evaluation of peroxiredoxins 1 and 2 along with the thioredoxin-thioredoxin reductase system as new therapeutic targets ...

Call: OPUS 4 , Panel: NZ7

Principal investigator: dr hab. Radosław Zagożdżon

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

PHARMACOTHERAPY OF OSTEOARTHRITIS: TRPV1 AND CB1 RECEPTORS AND THEIR ENDOGENOUS LIGANDS AS NEW TARGETS FOR PHARMACOLOGIC...

Call: SONATA BIS 2 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Starowicz-Bubak

Instytut Farmakologii PAN

Activation of endogenous pronociceptive mechanisms of opioid system as an important factors in the development of neurop...

Call: MAESTRO 3 , Panel: NZ4

Principal investigator: prof. Barbara Przewłocka

Instytut Farmakologii PAN

Identification of potential therapeutic targets in melanoma stem-like cells

Call: HARMONIA 3 , Panel: NZ2

Principal investigator: prof. Małgorzata Czyż

Uniwersytet Medyczny w Łodzi, Wydział Lekarski z Oddziałem Stomatologicznym

Automated recognition of opinion targets and expressions in Polish texts

Call: PRELUDIUM 3 , Panel: ST6

Principal investigator: dr Aleksander Wawer

Instytut Podstaw Informatyki Polskiej Akademii Nauk

Studies on non-linear laser-plasma interactions and generation of shocks in plasma for shock ignition of inertially conf...

Call: HARMONIA 2 , Panel: ST2

Principal investigator: prof. Jan Badziak

Instytut Fizyki Plazmy i Laserowej Mikrosyntezy im. Sylwestra Kaliskiego

PIM kinases as rational therapeutic targets in lymphoid malignancies.

Call: OPUS 2 , Panel: NZ4

Principal investigator: dr hab. Przemysław Juszczyński

Instytut Hematologii i Transfuzjologii

Pathogenesis of ovarian cancer survival in non-adhesion conditions: transcriptomic assessment and studies of molecular t...

Call: PRELUDIUM 2 , Panel: NZ1

Principal investigator: dr Anna Stachurska

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Targum Neofiti 1 to Genesis. Translation and critical edition.

Call: OPUS 2 , Panel: HS1

Principal investigator: dr hab. Mirosław Wróbel

Katolicki Uniwersytet Lubelski Jana Pawła II, Wydział Teologii

Two-body currents in the electron and neutrino scattering off few-nucleon targets

Call: IMPRESS-U , Panel: ST2

Principal investigator: prof. Jacek Golak

Uniwersytet Jagielloński

Mitochondrial targets of flozins in endothelial cells - a new approach to the prevention, diagnosis and therapy of heart...

Call: OPUS 26 , Panel: NZ4

Principal investigator: dr hab. Barbara Kutryb-Zając

Gdański Uniwersytet Medyczny, Wydział Lekarski

Extensive analysis of the immunological profile of pediatric patients with acute lymphoblastic leukemia in order to iden...

Call: PRELUDIUM 22 , Panel: NZ5

Principal investigator: Anna Krętowska-Grunwald

Uniwersytet Medyczny w Białymstoku

Directed screening and evaluation of novel bactericidal compounds active againsttubercle bacilli and Mycobacterium absce...

Call: OPUS 25 , Panel: NZ7

Principal investigator: prof. Jarosław Dziadek

Instytut Biologii Medycznej Polskiej Akademii Nauk

Computational deciphering of pro-ferroptotic cell death protein machinery as a fundamental step in the search for therap...

Call: SONATA BIS 12 , Panel: ST4

Principal investigator: dr Karolina Mikulska-Rumińska

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Omics-guided engineering of a secretory pathway for enhanced synthesis of secretory proteins in Yarrowia lipolytica - fu...

Call: PRELUDIUM 21 , Panel: NZ9

Principal investigator: Paulina Korpys-Woźniak

Uniwersytet Przyrodniczy w Poznaniu, Wydział Nauk o Żywności i Żywieniu

Role of RelA(p65) and cRel phosphorylations and their kinases in the biology of Diffuse-large B-cell lymphoma and Hodgki...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr Maciej Szydłowski

Instytut Hematologii i Transfuzjologii

Structural and functional studies of the plant enzymes of arginine metabolism as molecular targets of novel plant protec...

Call: SONATA 17 , Panel: NZ1

Principal investigator: dr Bartosz Sekuła

Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

Searching for new therapeutic targets in polyglutamine diseases

Call: OPUS 22 , Panel: NZ2

Principal investigator: dr hab. Marta Olejniczak

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

The biological role of sRNA OmrA and its impact on the level of virulence and adaptability of Yersinia enterocolitica en...

Call: PRELUDIUM BIS 3 , Panel: NZ6

Principal investigator: dr hab. Adrianna Raczkowska

Uniwersytet Warszawski, Wydział Biologii

Opioid receptors in the basal ganglia of the brain as targets for alcohol abuse therapy.

Call: OPUS 2 , Panel: NZ4

Principal investigator: dr Jan Rodriguez Parkitna

Instytut Farmakologii PAN

Mechanisms involved in heme acquisition - potential targets for therapies directed towards reduction of Porphyromonas gi...

Call: OPUS 21 , Panel: NZ6

Principal investigator: dr Michał Śmiga

Uniwersytet Wrocławski, Wydział Biotechnologii

In search for molecular targets to overcome doxorubicin resistance in triple-negative breast cancer with the use of inno...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Anna Pogorzelska

Narodowy Instytut Leków

Investigation and application of soft X-ray emission from targets containing micron-sized liquid droplets irradiated wit...

Call: OPUS 20 (LAP) , Panel: ST7

Principal investigator: prof. Henryk Fiedorowicz

Wojskowa Akademia Techniczna im. Jarosława Dąbrowskiego, Instytut Optoelektroniki

The study on the molecular mechanisms of cytotoxic activity of new compounds ZOT5-1-Me and ZOT5-1-Et in an experimental ...

Call: SONATA 16 , Panel: NZ7

Principal investigator: dr Paulina Tokarz

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Identification of surface proteins as alternate targets for CAR-T therapy against CD19-negative tumors.

Call: PRELUDIUM BIS 2 , Panel: NZ6

Principal investigator: dr hab. Magdalena Winiarska

Warszawski Uniwersytet Medyczny, Wydział Lekarski

Mechanisms controlling endocytosis of CD14 as targets for regulation of inflammatory responses of macrophages

Call: OPUS 20 , Panel: NZ3

Principal investigator: dr Anna Ciesielska

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

A network of liverwort-specific microRNAs and their targets in the sexual reproduction of Marchantia polymorpha

Call: OPUS 20 , Panel: NZ3

Principal investigator: prof. Zofia Szweykowska-Kulińska

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Toxic RNA with expanded trinucleotide repeats: pathomechanism and therapeutic targets of neurological diseases

Call: MAESTRO 12 , Panel: NZ3

Principal investigator: prof. Krzysztof Sobczak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Exploring new drug targets for efficacious therapy of neuropathic pain basing on the assessment and modulation of neuroi...

Call: OPUS 2 , Panel: NZ4

Principal investigator: dr hab. Joanna Mika

Instytut Farmakologii PAN

Novel aspects of virulence mechanisms of HopBF1, a bacterial effector that targets host HSP90 protein

Call: OPUS 19 , Panel: NZ1

Principal investigator: dr hab. Magdalena Krzymowska

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Screening for new therapeutic targets in inherited retinal diseases based on protein-protein interactions analysis

Call: POLS , Panel: NZ4

Principal investigator: dr Xiaonan Liu

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

New multifunctional drug-like ligands focusing on molecular targets associated with the symptoms and causes of Alzheimer...

Call: PRELUDIUM 19 , Panel: NZ7

Principal investigator: Anna Pasieka

Uniwersytet Jagielloński, Collegium Medicum

Novel L-asparaginases as potential therapeutic agents and antimicrobial targets: structural and functional studies of en...

Call: OPUS 19 , Panel: NZ1

Principal investigator: prof. Mariusz Jaskólski

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Understanding of the mesenchymal stem cells (MSCs)-mediated immune suppression mechanism in the neutrophilic experimenta...

Call: PRELUDIUM 19 , Panel: NZ5

Principal investigator: Marlena Tynecka

Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim