Projects funded by the NCN
From simple alkaloids to potentially anticancer Ir(III) and Ru(II) complexes supported by the magnetic nanoparticles.
2023/49/N/ST4/00337
Keywords:
phosphines alkaloids ruthenium(II) and iridium(III) complexes magnetic nanoparticles selective transport cytotoxicity biological activity
Descriptors:
- ST4_14:
- ST5_14:
Panel:
ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development
Host institution :
Uniwersytet Wrocławski, Wydział Chemii
woj. dolnośląskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 3
Call: PRELUDIUM 22 - announced on 2023-03-16
Amount awarded: 209 800 PLN
Project start date (Y-m-d): 2024-01-12
Project end date (Y-m-d): 2027-01-11
Project duration:: 36 months (the same as in the proposal)
Project status: Pending project
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- Bilosomal Encapsulation of Binuclear Phosphino Ru(II)–Cu(II) Compounds Enhances Their Selectivity and Activity toward Lung and Prostate CancersAuthors:Sandra Kozieł, Daria Wojtala, Agata Barzowska-Gogola, Barbara Pucelik, Ewelina Waglewska, Miłosz Siczek, Maciej Witwicki, Alessandro Niorettini, Agnieszka Kyzioł, Magdalena Malik, Urszula Bazylińska, Ewa Błaszczak, Urszula K. KomarnickaAcademic press:Journal of Medicinal Chemistry (rok: 2025, tom: 68, strony: 14442-14464), Wydawca: American Chemical SocietyStatus:PublishedDOI:10.1021/acs.jmedchem.5c00486 - link to the publication
- Half-Sandwich Organometallic Ir(III) and Ru(II) Compounds and their Interactions with BiomoleculesAuthors:Sandra Kozieł, Daria Wojtala, Magdalena Szmitka, Monika Lesiów, Aleksandra Ziółkowska, Jacek Sawka, Edgar Del Carpio, Debbie C. Crans, Urszula K. KomarnickaAcademic press:ChemPlusChem (rok: 2025, tom: 90, strony: e202400621, 1-23), Wydawca: Wiley-VCH GmbHStatus:PublishedDOI:10.1002/cplu.202400621 - link to the publication