Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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CHIRAL RHENIUM AND RHODIUM COMPLEXES OF ANTICANCER AND ANTIBACTERIAL ACTIVITY: SYNTHESIS, ACTIVITY, AND PHYSICOCHEMICAL PROPERTIES

2022/47/B/NZ7/02765

Keywords:

antitumor compounds chiral drugs non-platinum anticancer agents non-platinum antibacterial agents rhenium complexes rhodium complexes antibacterial activity physicochemical properties asymmetric synthesis chiroptical spectroscopy NMR spectroscopy X-ray diffractometry quantum-chemical calculations

Descriptors:

  • NZ7_014:
  • ST4_011:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Narodowy Instytut Leków

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jan Czesław Dobrowolski 

Number of co-investigators in the project: 13

Call: OPUS 24 - announced on 2022-07-15

Amount awarded: 2 672 074 PLN

Project start date (Y-m-d): 2023-09-01

Project end date (Y-m-d): 2027-08-31

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. Tricarbonyl rhenium(I) complexes with 8-hydroxyquinolines: structural, chemical, antibacterial, and anticancer characteristics
    Authors:
    Krzysztof Łyczko, Anna Pogorzelska, Urszula Częścik, Mirosława, Koronkiewicz, Joanna E. Rode, Elżbieta Bednarek, Robert Kawęcki, Karolina Węgrzyńska, Anna Baraniak, Małgorzata Milczarek, Jan Cz. Dobrowolski
    Academic press:
    RSC Advances (rok: 2024, tom: 14, strony: 18080−18092), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D4RA03141E - link to the publication