Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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A new approach for gene delivery into retinal bipolar cells

2022/47/B/NZ5/03023

Keywords:

retina bipolar cells LRIT3 pseudotyped Rabies virus congenital stationary night blindness (cCSNB)

Descriptors:

  • NZ5_007:
  • NZ5_008:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Chemii Fizycznej Polskiej Akademii Nauk, Międzynarodowe Centrum Badań Oka

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Andrzej Tomasz Foik 

Number of co-investigators in the project: 6

Call: OPUS 24 - announced on 2022-07-15

Amount awarded: 4 224 291 PLN

Project start date (Y-m-d): 2023-06-14

Project end date (Y-m-d): 2027-06-13

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations
    Authors:
    Hołubowicz R, Du SW, Felgner J, Smidak R, Choi EH, Palczewska G, Menezes CR, Dong Z, Gao F, Medani O, Yan AL, Hołubowicz MW, Chen PZ, Bassetto M, Risaliti E, Salom D, Workman JN, Kiser PD, Foik AT, Lyon DC, Newby GA, Liu DR, Felgner PL, Palczewski K.
    Academic press:
    Nature Biomedical Engineering (rok: 2024, tom: 9(1), strony: 57-78), Wydawca: Nature Portfolio
    Status:
    Published
    DOI:
    10.1038/s41551-024-01296-2 - link to the publication
  2. In vivo volumetric analysis of retinal vascular hemodynamics in mice with spatio-temporal optical coherence tomography
    Authors:
    Węgrzyn P, Kulesza W, Wielgo M, Tomczewski S, Galińska A, Bałamut B, Kordecka K, Cetinkaya O, Foik A, Zawadzki RJ, Borycki D, Wojtkowski M, Curatolo A
    Academic press:
    Neurophotonics (rok: 2024, tom: 11(4), strony: 0450031-4500322), Wydawca: SPIE
    Status:
    Published
    DOI:
    10.1117/1.NPh.11.4.045003 - link to the publication

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