Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Thermodynamics of modified RNAs. Impact of RNA modifications on structure and function of natural RNA and vaccine-type in vitro transcribed mRNA (IVT mRNA).

2022/45/B/ST4/03586

Keywords:

RNA structure thermodynamics of RNA pseudouridine N1-methylpseudouridine chemical mapping of RNA structure IVT mRNA vaccines nanopore RNA sequencing

Descriptors:

  • ST4_9: Biological chemistry
  • ST4_3: Molecular architecture and structure
  • NZ1_4: Structural biology

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Ryszard Kierzek 

Number of co-investigators in the project: 6

Call: OPUS 23 - announced on 2022-03-28

Amount awarded: 2 685 220 PLN

Project start date (Y-m-d): 2023-03-01

Project end date (Y-m-d): 2027-02-28

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.