Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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MOF-antidote": Novel detoxification materials based on metal organic-frameworks for drugs of abuse removal - synthesis, chemical characterization, toxicity and efficacy in in vivo and in vitro studies

2021/43/B/NZ7/00827

Keywords:

metal-organic frameworks detoxication drug delivery in vivo in vitro

Descriptors:

  • NZ7_015:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Politechnika Krakowska im. Tadeusza Kościuszki

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Przemysław Jakub Jodłowski 

Number of co-investigators in the project: 7

Call: OPUS 22 - announced on 2021-09-15

Amount awarded: 1 884 560 PLN

Project start date (Y-m-d): 2022-09-01

Project end date (Y-m-d): 2025-08-31

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  • Book publications / chapters in book publications (1)
  1. Metal-organic frameworks for efficient mephedrone detoxification or supervised withdrawal – synthesis, characterisation, and in vivo studies
    Authors:
    K. Hyjek, G. Kurowski, K. Dymek, A. Boguszewska-Czubara, B. Budzyńska, O. Wronikowska-Denysiuk, A. Gajda, W. Piskorz, P. Śliwa, M. Szumera, P. Jeleń, M. Sitarz, P.J. Jodłowski
    Academic press:
    Chemical Engineering Journal (rok: 2024, tom: 479, strony: 147655 Contents), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.cej.2023.147655 - link to the publication
  2. In vivo and in vitro studies of efficient mephedrone adsorption over zirconium-based metal-organic frameworks corroborated by DFT+D modeling
    Authors:
    P.J. Jodłowski, K. Dymek, G. Kurowski, K. Hyjek, A. Boguszewska-Czubara, B. Budzyńska, A. Pajdak, Ł. Kuterasiński, W. Piskorz, P. Jeleń, M. Sitarz
    Academic press:
    Microporous and Mesoporous Materials (rok: 2023, tom: 359, strony: 112647), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.micromeso.2023.112647 - link to the publication
  3. Metal-organic frameworks for efficient drug adsorption and delivery
    Authors:
    K. Hyjek, P. Jodłowski
    Academic press:
    Scientiae Radices (rok: 2023, tom: 2, strony: 118-189), Wydawca: Radom Scientific Society
    Status:
    Published
    DOI:
    10.58332/scirad2023v2i2a03 - link to the publication
  4. Crystal Clear: Metal–Organic Frameworks Pioneering the Path to Future Drug Detox
    Authors:
    Jodłowski, P. J.; Dymek, K.; Kurowski, G.; Hyjek, K.; Boguszewska-Czubara, A.; Budzyńska, B.; Mrozek, W.; Skoczylas, N.; Kuterasiński, Ł.; Piskorz, W.; Białoruski, M.; Jędrzejczyk, R. J.; Jeleń, P.; Sitarz, M.
    Academic press:
    ACS Applied Materials & Interfaces (rok: 2024, tom: 16, strony: 29657-29671), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acsami.4c02450 - link to the publication
  5. From crystal phase mixture to pure metal-organic frameworks – Tuning pore and structure properties
    Authors:
    Jodłowski, P. J.; Kurowski, G.; Dymek, K.; Oszajca, M.; Piskorz, W.; Hyjek, K.; Wach, A.; Pajdak, A.; Mazur, M.; Rainer, D. N.; Wierzbicki, D.; Jeleń, P.; Sitarz
    Academic press:
    Ultrasonics Sonochemistry (rok: 2023, tom: 95, strony: 106377), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ultsonch.2023.106377 - link to the publication
  1. A BRIEF OVERVIEW ON METAL-ORGANIC FRAMEWORK - SYNTHESIS, CHARACTERIZATION AND APPLICATION FOR MEDICINE PURPOSES
    Authors:
    Hyjek K, Jodłowski P. J.
    Book:
    Chemical and Process Engineering for Environment and Health, Current status in 2024 (rok: 2024, tom: -, strony: 153-164), Wydawca: Publishing House of Łukasiewicz - Institute for Sustainable Technologies
    Status:
    Published

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