Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

The role of impaired autophagy and peroxisome function in NAFLD development and their targeted recovery for improved efficacy of n-3 fatty acids.

2021/43/I/NZ3/00510

Keywords:

Nonalcoholic Fatty Liver Disease (NAFLD) autophagy peroxisomes n-3 fatty acids

Descriptors:

  • NZ3_002:
  • NZ1_002:

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Mariusz Roman Więckowski 

Number of co-investigators in the project: 9

Call: OPUS 22 (LAP) - announced on 2021-09-15

Amount awarded: 2 695 590 PLN

Project start date (Y-m-d): 2022-07-27

Project end date (Y-m-d): 2026-07-26

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. The Interplay between Endogenous and Foodborne Pro-Oxidants and Antioxidants in Shaping Redox Homeostasis.
    Authors:
    Jakubek P, Parchem K, Wieckowski MR, Bartoszek A.
    Academic press:
    International Journal of Molecular Sciences (rok: 2024, tom: 25(14), strony: 11689), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms25147827 - link to the publication
  2. Autophagy alterations in obesity, type 2 diabetes, and metabolic dysfunction-associated steatotic liver disease: the evidence from human studies
    Authors:
    Jakubek P, Pakula B, Rossmeisl M, Pinton P, Rimessi A, Wieckowski MR.
    Academic press:
    Internal and Emergency Medicine (rok: 2024, tom: 19(5), strony: 1473-1491), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s11739-024-03700-w - link to the publication
  3. Oxidative stress in metabolic dysfunction-associated steatotic liver disease (MASLD): How does the animal model resemble human disease?
    Authors:
    Jakubek P, Kalinowski P, Karkucinska-Wieckowska A, Kaikini A, Simões ICM, Potes Y, Kruk B, Grajkowska W, Pinton P, Milkiewicz P, Grąt M, Pronicki M, Lebiedzinska-Arciszewska M, Krawczyk M, Wieckowski MR.
    Academic press:
    The FASEB Journal (rok: 2024, tom: 38(3), strony: 45672), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1096/fj.202302447R - link to the publication
  4. Influence of Lipid Class Used for Omega-3 Fatty Acid Supplementation on Liver Fat Accumulation in MASLD.
    Authors:
    Sabinari I, Horakova O, Cajka T, Kleinova V, Wieckowski MR, Rossmeisl M.
    Academic press:
    Physiological Research (rok: 2024, tom: 73, strony: 295-320), Wydawca: the Institute of Physiology of the Czech Academy of Sciences, Prague, Czech Republic
    Status:
    Published
    DOI:
    10.33549/physiolres.935396 - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy