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The role of hypoxia-sensitive miRNA181a, miRNA199a, and SIRT1 in diabetes mellitus development in obstructive sleep apnea patients

2021/41/N/NZ5/00486

Keywords:

obstructive sleep apnea diabetes mellitus hypoxia epigenetics SIRT1 microRNA pathophysiology

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ5_5: Diagnostics in human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

Filip Franciszek Karuga 

Number of co-investigators in the project: 3

Call: PRELUDIUM 20 - announced on 2021-03-15

Amount awarded: 210 000 PLN

Project start date (Y-m-d): 2022-01-11

Project end date (Y-m-d): 2025-01-10

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. The role of microRNAs in pathophysiology and diagnostics of metabolic complications in obstructive sleep apnea patients
    Authors:
    Filip Karuga, Julia Jaromirska, Mikołaj Malicki, Marcin Sochal, Bartosz Szmyd, Piotr Białasiewicz, Dominik Strzelecki, Agata Gabryelska
    Academic press:
    Frontiers in Molecular Neuroscience (rok: 2023, tom: 16, strony: publikacja online), Wydawca: Frontiers
    Status:
    Published
    DOI:
    link to the publication
  2. Obstructive Sleep Apnea, Circadian Clock Disruption, and Metabolic Consequences
    Authors:
    Mikołaj Malicki †, Filip Franciszek Karuga †, Bartosz Szmyd, Marcin Sochal, Agata Gabryelska
    Academic press:
    Metabolites (rok: 2022, tom: 13(1) 60, strony: publikacja online), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/metabo13010060 - link to the publication
  3. Obstructive Sleep Apnea, Circadian Clock Disruption, and Metabolic Consequences
    Authors:
    Mikołaj Malicki †, Filip Franciszek Karuga †, Bartosz Szmyd, Marcin Sochal, Agata Gabryelska
    Academic press:
    Metabolites (rok: 2022, tom: 13(1) 60, strony: publikacja online), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/metabo13010060 - link to the publication

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