Projects funded by the NCN
Switchable with visible light cisplatin analogs and complexes of selected transition metals - photochemical and anticancer activity in vitro
2021/41/B/NZ7/02484
Keywords:
Photoswitch cis-trans photoisomerization arylazopyrazoles cisplatin coordination complexes cytotoxicity anticancer
Descriptors:
- ST4_012:
- ST4_011:
- NZ7_014:
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Uniwersytet Jagielloński, Wydział Chemii
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 6
Call: OPUS 21 - announced on 2021-03-15
Amount awarded: 1 655 646 PLN
Project start date (Y-m-d): 2022-04-01
Project end date (Y-m-d): 2026-03-31
Project duration:: 48 months (the same as in the proposal)
Project status: Pending project
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Light-Controlled Anticancer Activity and Cellular Uptake of a Photoswitchable Cisplatin AnalogueAuthors:Marta Stolarek, Kamil Kaminski, Marta Kaczor-Kamińska, Magdalena Obłoza, Piotr Bonarek, Anna Czaja, Magdalena Datta, Wojciech Łach, Mateusz Brela, Artur Sikorski, Janusz Rak, Maria Nowakowska, Krzysztof Szczubiałka*Academic press:Journal of Medicinal Chemistry (rok: 2024, tom: 67, strony: 19103-19120), Wydawca: American Chemical SocietyStatus:PublishedDOI:10.1021/acs.jmedchem.4c01575 - link to the publication