Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Development of methods of isotope-labeled standards preparation for their quantitative analysis by LC-MS in selected drugs and their metabolites

2021/41/N/ST4/00767

Keywords:

LC-MS isotopic labeling hydrogen-deuterium exchange

Descriptors:

  • ST4_5: Analytical chemistry
  • ST4_2: Spectroscopic and spectrometric techniques
  • ST4_8: Organic chemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Wrocławski, Wydział Chemii

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

Paulina Zamiara 

Number of co-investigators in the project: 2

Call: PRELUDIUM 20 - announced on 2021-03-15

Amount awarded: 210 000 PLN

Project start date (Y-m-d): 2022-01-18

Project end date (Y-m-d): 2025-01-17

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (6)
  1. Preparation of Deuterium-Labeled Armodafinil by Hydrogen–Deuterium Exchange and Its Application in Quantitative Analysis by LC-MS
    Authors:
    Grocholska Paulina, Wieczorek Robert, Bąchor Remigiusz
    Academic press:
    Metabolites (rok: 2022, tom: 12, strony: 578/1-578/18), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/metabo12070578 - link to the publication
  2. Preparation of Deuterium-Labeled Armodafinil by Hydrogen–Deuterium Exchange and Its Application in Quantitative Analysis by LC-MS
    Authors:
    Grocholska Paulina, Wieczorek Robert, Bąchor Remigiusz
    Academic press:
    Metabolites (rok: 2022, tom: 12, strony: 578/1-578/18), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/metabo12070578 - link to the publication
  3. Citius, Altius, Fortius—Advanced Mass Spectrometry in Service of Forensic Analysis
    Authors:
    Grocholska Paulina, Popiel Dominik, Walter Martyna, Biernat Monika, Cebrat Marek, Kuczer Mariola, Modzel Maciej, Bąchor Remigiusz, Kluczyk Alicja
    Academic press:
    Chemosensors (rok: 2022, tom: 10, strony: 324/1-324/33), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/chemosensors10080324 - link to the publication
  4. Citius, Altius, Fortius—Advanced Mass Spectrometry in Service of Forensic Analysis
    Authors:
    Grocholska Paulina, Popiel Dominik, Walter Martyna, Biernat Monika, Cebrat Marek, Kuczer Mariola, Modzel Maciej, Bąchor Remigiusz, Kluczyk Alicja
    Academic press:
    Chemosensors (rok: 2022, tom: 10, strony: 324/1-324/33), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/chemosensors10080324 - link to the publication
  5. Qualitative and Quantitative Mass Spectrometry in Salivary Metabolomics and Proteomics
    Authors:
    Grocholska Paulina, Kowalska Marta, Bąchor Remigiusz
    Academic press:
    Metabolites (rok: 2023, tom: 13, strony: 155/1-155/25), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/metabo13020155 - link to the publication
  6. Qualitative and Quantitative Mass Spectrometry in Salivary Metabolomics and Proteomics
    Authors:
    Grocholska Paulina, Kowalska Marta, Bąchor Remigiusz
    Academic press:
    Metabolites (rok: 2023, tom: 13, strony: 155/1-155/25), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/metabo13020155 - link to the publication

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