Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Homeostatic plasticity of the mitochondrial proteome and lipidome upon stress

2021/40/C/NZ3/00283

Keywords:

Mitochondrial Plasticity / Mitochondrial Stress Responses / Mitochondrial Quality Control / Regain of Homeostasis / Mass Spectrometry / Native Mass Spectrometry / Proteomics / Lipidomics / Multiomics

Descriptors:

  • NZ3_1: Cell biology
  • NZ2_3: Proteomics
  • NZ2_4: Metabolomics

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Vanessa Puchalska Linke 

Number of co-investigators in the project: 2

Call: SONATINA 5 - announced on 2020-12-15

Amount awarded: 893 126 PLN

Project start date (Y-m-d): 2021-12-15

Project end date (Y-m-d): 2024-12-14

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut.
    Authors:
    Zhang Q*, Linke V*, Overmyer KA, Traeger LL, Kasahara K, Miller IJ, Manson DE, Polaske TJ, Kerby RL, Kemis JH, Trujillo EA, Reddy TR, Russell JD, Schueler KL, Stapleton DS, Rabaglia ME, Seldin M, Gatt DMi, Keele GR, Pham DT, Gerdt JP, Vivas EI, Lusis AJ, Keller MP, Churchill GA, Blackwell HE, Broman KW, Attie AD, Coon JJ, Rey FE
    Academic press:
    Nature Microbiology (rok: 2023, tom: 8, strony: 424–440), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41564-023-01326-w - link to the publication