Projects funded by the NCN
Aggregates of toxic polyglycine protein: in the spotlight. Understanding of formation and degradation processes.
2021/40/C/NZ3/00323
Keywords:
polyglycine protein Fragile X-associated tramor/ataxia syndrome protein aggregation nuclear inclusions CGG repeat expansion microsatellite expansion disorders super-resolution microscopy high-throughput screening
Descriptors:
- NZ3_6: Cell neurobiology
- NZ1_1: Molecular biology
- NZ5_3: Pathogenesis of human diseases
Panel:
NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution :
Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
woj.
Principal investigator (from the host institution):
Number of co-investigators in the project: 4
Call: SONATINA 5 - announced on 2020-12-15
Amount awarded: 1 117 308 PLN
Project start date (Y-m-d): 2021-10-04
Project end date (Y-m-d): 2024-10-03
Project duration:: 36 months (the same as in the proposal)
Project status: Project completed
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Partners in crime: Proteins implicated in RNA repeat expansion diseasesAuthors:Anna Baud, Magdalena Derbis, Katarzyna Tutak, Krzysztof SobczakAcademic press:Wiley Interdisciplinary Reviews RNA (rok: 2022, tom: 13, strony: e1709), Wydawca: WileyStatus:PublishedDOI:10.1002/wrna.1709 - link to the publication