Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Identification of cancer-driver mutations in non-coding parts of protein-coding genes and long non-coding RNA genes

2020/39/B/NZ5/01970

Keywords:

somatic mutations lung cancer non-coding RNA untranslated regions 5'UTR 3'UTR introns lncRNAs

Descriptors:

  • NZ5_5: Diagnostics in human diseases
  • NZ2_11: Genetic epidemiology
  • NZ2_2: Genomics, transcriptomics, epigenomics

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Piotr Kozłowski 

Number of co-investigators in the project: 5

Call: OPUS 20 - announced on 2020-09-15

Amount awarded: 2 755 600 PLN

Project start date (Y-m-d): 2021-08-24

Project end date (Y-m-d): 2025-08-23

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (8)
  1. Consequences of genetic variants in miRNA genes
    Authors:
    Machowska M, Gałka-Marciniak P, Kozłowski P
    Academic press:
    Computational and Structural Biotechnology Journal (rok: 2022, tom: 20, strony: 6443-6457), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.csbj.2022.11.036 - link to the publication
  2. Mutations in the mir-142 gene are not common in myeloproliferative neoplasms
    Authors:
    Gałka-Marciniak P, Kanduła Z, Tiré A, Węgorek W, Gwóźdź-Bąk K, Handschuh L, Giefing M, Lewandowski K, Kozłowski P
    Academic press:
    Scientific Reports (rok: 2022, tom: 12(1), strony: 10924), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-022-15162-1 - link to the publication
  3. Profile of basal cell carcinoma mutations and copy number alterations- focus on gene-associated noncoding variants
    Authors:
    Nawrocka PM, Gałka-Marciniak P, Urbanek-Trzeciak MO, M-Thirusenthilarasan I, Szóstak N, Philips A, Susok L, Sand M, Kozłowski P
    Academic press:
    Frontiers in Oncology (rok: 2021, tom: 11, strony: 752579), Wydawca: Frontiers Media SA
    Status:
    Published
    DOI:
    10.3389/fonc.2021.752579 - link to the publication
  4. Mutations in the mir-142 gene are not common in myeloproliferative neoplasms
    Authors:
    Gałka-Marciniak P, Kanduła Z, Tiré A, Węgorek W, Gwóźdź-Bąk K, Handschuh L, Giefing M, Lewandowski K, Kozłowski P
    Academic press:
    Scientific Reports (rok: 2022, tom: 12(1), strony: 10924), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-022-15162-1 - link to the publication
  5. Profile of basal cell carcinoma mutations and copy number alterations- focus on gene-associated noncoding variants
    Authors:
    Nawrocka PM, Gałka-Marciniak P, Urbanek-Trzeciak MO, M-Thirusenthilarasan I, Szóstak N, Philips A, Susok L, Sand M, Kozłowski P
    Academic press:
    Frontiers in Oncology (rok: 2021, tom: 11, strony: 752579), Wydawca: Frontiers Media SA
    Status:
    Published
    DOI:
    10.3389/fonc.2021.752579 - link to the publication
  6. miRMut: Annotation of mutations in miRNA genes from human whole-exome or whole-genome sequencing
    Authors:
    Urbanek-Trzeciak MO, Kozłowski P, Gałka-Marciniak P
    Academic press:
    STAR PROTOCOLS (rok: 2021, tom: 3(1), strony: 101023), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.xpro.2021.101023 - link to the publication
  7. miRMut: Annotation of mutations in miRNA genes from human whole-exome or whole-genome sequencing
    Authors:
    Urbanek-Trzeciak MO, Kozłowski P, Gałka-Marciniak P
    Academic press:
    STAR PROTOCOLS (rok: 2021, tom: 3(1), strony: 101023), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.xpro.2021.101023 - link to the publication
  8. Consequences of genetic variants in miRNA genes
    Authors:
    Machowska M, Gałka-Marciniak P, Kozłowski P
    Academic press:
    Computational and Structural Biotechnology Journal (rok: 2022, tom: 20, strony: 6443-6457), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.csbj.2022.11.036 - link to the publication

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