Projects funded by the NCN
Epigenetic modultion of S1P/S1PR1 signaling pathway in colonic inflammation and neoplastic transformation in patients with primary sclerosing cholangitis.
2020/39/O/NZ4/01732
Keywords:
cholestatic liver diseases colonic inflammation microRNA sphingosine-1-phosphate STAT3
Descriptors:
- NZ4_12: Other related subjects
- NZ4_5: Anatomical pathology
- NZ5_3: Pathogenesis of human diseases
Panel:
NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution :
Pomorski Uniwersytet Medyczny w Szczecinie
woj.
Principal investigator (from the host institution):
dr hab. Agnieszka Daniela Kempińska-Podhorodecka
Number of co-investigators in the project: 2
Call: PRELUDIUM BIS 2 - announced on 2020-09-15
Amount awarded: 540 460 PLN
Project start date (Y-m-d): 2022-12-09
Project end date (Y-m-d): 2026-12-08
Project duration:: 48 months (the same as in the proposal)
Project status: Pending project
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (3)
- The role of hsa-miR-125b-5p interaction with S1P/ceramide axis in the potential development of inflammation-associated colon cancer in primary sclerosing cholangitisAuthors:Abramczyk Joanna, Milkiewicz Małgorzata, Hula Bartosz, Milkiewicz Piotr, Kempińska-Podhorodecka AgnieszkaAcademic press:Int. J. Mol. Sci (rok: 2023, tom: vol. 24, nr 11, id. art. 9175, strony: 15 s.), Wydawca: MDPIStatus:PublishedDOI:10.3390/ijms24119175 - link to the publication
- Modulation of mismatch repair and the SOCS1/p53 axis by microRNA-155 in the colon of patients with primary sclerosing cholangitisAuthors:Adamowicz Monika, Stukan Iga, Milkiewicz Piotr, Białek Andrzej, Milkiewicz Małgorzata, Kempińska-Podhorodecka AgnieszkaAcademic press:Int. J. Mol. Sci. (rok: 2022, tom: vol. 23, nr 9, strony: art. 4905), Wydawca: MDPIStatus:PublishedDOI:10.3390/ijms23094905 - link to the publication
- 5-aminosalicylic acid inhibits the expression of oncomirs and pro-inflammatory microRNAs: an in vitro study.Authors:Adamowicz Monika, Milkiewicz Piotr, Kempińska-Podhorodecka AgnieszkaAcademic press:Physiol. Pharmacol. (rok: 2021, tom: vol. 72, nr 4, strony: 7 s.), Wydawca: J. Physiol. Pharmacol.Status:PublishedDOI:10.26402/jpp.2021.4.04 - link to the publication