Projects funded by the NCN
Effects of a cancer metabolite on immune response
2020/39/B/NZ6/03513
Keywords:
immune response cancer metabolism
Descriptors:
- NZ6_001:
Panel:
NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology
Host institution :
Warszawski Uniwersytet Medyczny, Wydział Lekarski
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 6
Call: OPUS 20 - announced on 2020-09-15
Amount awarded: 2 596 658 PLN
Project start date (Y-m-d): 2021-07-08
Project end date (Y-m-d): 2025-07-07
Project duration:: 48 months (the same as in the proposal)
Project status: Project completed
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Articles in post-conference publications (1)
- Potassium/sodium cation carriers robustly up-regulate CD20 antigen by targeting MYC, and synergize with anti-CD20 immunotherapies to eliminate malignant B cells.Authors:Torun A., Zdanowicz A., Miazek-Zapala N., Zapala P., Pradhan B., Jedrzejczyk M., Ciechanowicz A., Pilch Z., Skorzynski M., Słabicki M., Rymkiewicz G., Barankiewicz J., Martines C., Laurenti L., Struga M., Winiarska M., Golab J., Kucia M., Ratajczak M.Z., Huczynski A., Calado D.P., Efremov D.G., Zerrouqi A., and Pyrzynska B.Academic press:Haematologica (rok: 2024, tom: Haematologica Early view Dec 19, 2024, strony: 46053), Wydawca: Ferrata-Storti FoundationStatus:PublishedDOI:10.3324/haematol.2024.285826 - link to the publication
- Improvement of the anti-tumor activity of NK cells and the efficacy of anti-CD20 monoclonal antibodies in the therapy of B cell-derived malignancies.Authors:Zerrouqi A., Zdanowicz A., Torun A., Ciechanowicz A., Pradhan B., Rymkiewicz G., Efremov D., and Pyrzynska B.Conference:Cancer Research, Vol. 84 (6_Suppl) (rok: 2024, tom: AACR Annual Meeting 2024, strony: Abstract no 1344), Wydawca: American Association for Cancer ResearchData:konferencja 5-10/04/2024Status:PublishedDOI:10.1158/1538-7445.AM2024-1344 - link to the publication