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Information of the project and the call

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Mucoadhesive delivery systems of polyphenols as an effective way to increase their health-promoting properties

2020/39/D/NZ7/01824

Keywords:

polyphenols mucoadhesion electrospinning extrusion

Descriptors:

  • NZ7_014:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Magdalena Paczkowska-Walendowska 

Number of co-investigators in the project: 4

Call: SONATA 16 - announced on 2020-09-15

Amount awarded: 1 207 190 PLN

Project start date (Y-m-d): 2021-10-04

Project end date (Y-m-d): 2025-10-03

Project duration:: 48 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (15)
  1. Cyclodextrin as Functional Carrier in Development of Mucoadhesive Tablets Containing Polygoni cuspidati Extract with Potential for Dental Applications
    Authors:
    Magdalena Paczkowska-Walendowska ,Emilia Szymańska ,Katarzyna Winnicka ,Dominik Szwajgier, Ewa Baranowska-Wójcik, Marek A. Ruchała, Marek Simon, Judyta Cielecka-Piontek
    Academic press:
    Pharmaceutics (rok: 2021, tom: 13, strony: 1916), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics13111916 - link to the publication
  2. Blackberry Leaves as New Functional Food? Screening Antioxidant, Anti-Inflammatory and Microbiological Activities in Correlation with Phytochemical Analysis
    Authors:
    Magdalena Paczkowska-Walendowska, Anna Gościniak, Daria Szymanowska, Dominik Szwajgier, Ewa Baranowska-Wójcik, Piotr Szulc, Dagna Dreczka, Marek Simon, Judyta Cielecka-Piontek
    Academic press:
    Antioxidants (rok: 2021, tom: 10, strony: 1945), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/antiox10121945 - link to the publication
  3. Hot melt extrusion as an effective process in the development of mucoadhesive tablets containing Scutellariae baicalensis radix extract and chitosan dedicated to the treatment of oral infections
    Authors:
    Magdalena Paczkowska-Walendowska, Andrzej Miklaszewski, Daria Szymanowska, Krystyna Skalicka-Woźniak, Judyta Cielecka-Piontek
    Academic press:
    Int. J. Mol. Sci (rok: 2023, tom: 24, strony: 5834), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms24065834 - link to the publication
  4. Electrospun Nanofibers Loaded with Marigold Extract Based on PVP/HPβCD and PCL/PVP Scaffolds for Wound Healing Applications
    Authors:
    Magdalena Paczkowska-Walendowska, Natalia Rosiak, Tomasz Plech, Tomasz Karpiński, Andrzej Miklaszewski, Katarzyna Witkowska, Maciej Jaskólski, Cansu Erdem, Judyta Cielecka-Piontek
    Academic press:
    Materials (rok: 2024, tom: 17, strony: 1736), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma17081736 - link to the publication
  5. 3D-Printed Chitosan-Based Scaffolds with Scutellariae baicalensis Extract for Dental Applications
    Authors:
    Magdalena Paczkowska-Walendowska, Ioanna Koumentakou, Maria Lazaridou, Dimitrios Bikiaris, Andrzej Miklaszewski, Tomasz Plech, Judyta Cielecka-Piontek
    Academic press:
    Pharmaceutics (rok: 2024, tom: 16, strony: 359), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics16030359 - link to the publication
  6. Chitosan-Based Hydrogels for Controlled Delivery of Asiaticoside-Rich Centella asiatica Extracts with Wound Healing Potential
    Authors:
    Katarzyna Witkowska,Magdalena Paczkowska-Walendowska,Tomasz Plech, Daria Szymanowska, Bożena Michniak-Kohn, Judyta Cielecka-Piontek
    Academic press:
    Int. J. Mol. Sci. (rok: 2023, tom: 24, strony: 17229), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms242417229 - link to the publication
  7. The Antioxidant Potential of Resveratrol from Red Vine Leaves Delivered in an Electrospun Nanofiber System
    Authors:
    Magdalena Paczkowska-Walendowska, Andrzej Miklaszewski, Bożena Michniak-Kohn, Judyta Cielecka-Piontek
    Academic press:
    Antioxidants (rok: 2023, tom: 12, strony: 1777), Wydawca: MPDI
    Status:
    Published
    DOI:
    10.3390/antiox12091777 - link to the publication
  8. Electrospun Nanofibers with Pomegranate Peel Extract as a New Concept for Treating Oral Infections
    Authors:
    Magdalena Paczkowska-Walendowska, Miłosz Ignacyk, Andrzej Miklaszewski, Tomasz Plech, Tomasz M. Karpiński, Jakub Kwiatek, Ewelina Swora-Cwynar, Michał Walendowski, Judyta Cielecka-Piontek
    Academic press:
    Materials (rok: 2024, tom: 17, strony: 2558), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma17112558 - link to the publication
  9. Improving Solubility and Permeability of Hesperidin through Electrospun Orange-Peel-Extract-Loaded Nanofibers
    Authors:
    Magdalena Paczkowska-Walendowska, Andrzej Miklaszewski, Daria Szymanowska, Krystyna Skalicka-Woźniak, Judyta Cielecka-Piontek
    Academic press:
    Int. J. Mol. Sci. (rok: 2023, tom: 24, strony: 7963), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms24097963 - link to the publication
  10. Chitosan as a functional carrier for the local delivery anti-inflammatory systems containing Scutellariae baicalensis radix extract
    Authors:
    Magdalena Paczkowska-Walendowska, Judyta Cielecka-Piontek
    Academic press:
    Pharmaceutics (rok: 2022, tom: 14, strony: 2148), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics14102148 - link to the publication
  11. Mechanochemical Properties of Mucoadhesive Tablets Based on PVP/HPβCD Electrospun Nanofibers as Local Delivery of Polygoni cuspidati Extract for Treating Oral Infections
    Authors:
    Magdalena Paczkowska-Walendowska, Daria Szymanowska, Judyta Cielecka-Piontek
    Academic press:
    Pharmaceuticals (rok: 2023, tom: 16, strony: 579), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ph16040579 - link to the publication
  12. Implementing the Design of Experiments (DoE) Concept into the Development of Mucoadhesive Tablets Containing Orange Peel Extract as a Potential Concept for the Treatment of Oral Infections
    Authors:
    Magdalena Paczkowska-Walendowska, Tomasz M. Karpiński, Ewa Garbiec, Michał Walendowski, Judyta Cielecka-Piontek
    Academic press:
    Materials (rok: 2024, tom: 17, strony: 5234), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma17215234 - link to the publication
  13. Is it possible to improve the bioavailability of resveratrol and polydatin derived from Polygoni cuspidati radix as a result of preparing electrospun nanofibers based on polyvinylpyrrolidone/cyclodextrin?
    Authors:
    Magdalena Paczkowska-Walendowska, Andrzej Miklaszewski, Judyta Cielecka-Piontek
    Academic press:
    Nutrients (rok: 2022, tom: 14, strony: 3897), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nu14193897 - link to the publication
  14. Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy
    Authors:
    Katarzyna Witkowska, Magdalena Paczkowska-Walendowska, Ewa Garbiec, Judyta Cielecka-Piontek
    Academic press:
    Pharmaceutics (rok: 2024, tom: 16, strony: 1252), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics16101252 - link to the publication
  15. Hot melt extrusion for improving the physicochemical properties of polydatin derived from Polygoni cuspidati extract; a solution recommended for buccal applications
    Authors:
    Magdalena Paczkowska-Walendowska, Lidia Tajber, Andrzej Miklaszewski, Judyta Cielecka-Piontek
    Academic press:
    Pharmaceuticals (rok: 2023, tom: 16, strony: 1226), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ph16091226 - link to the publication

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