Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Microenvironment in differentiation and maturation of human pancreatic endocrine cells

2020/39/B/NZ3/01408

Keywords:

pancreas beta-cells human pluripotent stem cells pancreatic differentiation mesenchyme endothelial cells pancreatic niche WNT5A signaling pancreatic microennviroment

Descriptors:

  • NZ3_9: Organogenesis
  • NZ3_8: Stem cell biology
  • NZ3_13: Developmental biology in animals

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Małgorzata Borowiak 

Number of co-investigators in the project: 6

Call: OPUS 20 - announced on 2020-09-15

Amount awarded: 2 858 834 PLN

Project start date (Y-m-d): 2021-06-24

Project end date (Y-m-d): 2025-06-23

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Diabetes and SARS- CoV-2-Is There a Mutual Connection?
    Authors:
    Jedrzejak AP, Urbaniak EK, Wasko JA, Ziojla N, Borowiak M.
    Academic press:
    Frontiers in Cell and Developmental Biology (rok: 2022, tom: 10, strony: 913305), Wydawca: Frontiers Media S.A.
    Status:
    Published
    DOI:
    10.3389/fcell.2022.913305 - link to the publication
  2. Diabetes and SARS- CoV-2-Is There a Mutual Connection?
    Authors:
    Jedrzejak AP, Urbaniak EK, Wasko JA, Ziojla N, Borowiak M.
    Academic press:
    Frontiers in Cell and Developmental Biology (rok: 2022, tom: 10, strony: 913305), Wydawca: Frontiers Media S.A.
    Status:
    Published
    DOI:
    10.3389/fcell.2022.913305 - link to the publication
  3. Human pancreatic microenvironment promotes β-cell differentiation via non-canonical WNT5A/JNK and BMP signaling
    Authors:
    Chmielowiec J, Szlachcic WJ, Yang D, Scavuzzo MA, Wamble K, Sarrion-Perdigones A, Sabek OM, Venken KJT, Borowiak M
    Academic press:
    Nature Communications (rok: 2022, tom: 13(1), strony: 1952), Wydawca: Springer Nature Limited
    Status:
    Published
    DOI:
    10.1038/s41467-022-29646-1 - link to the publication
  4. Human pancreatic microenvironment promotes β-cell differentiation via non-canonical WNT5A/JNK and BMP signaling
    Authors:
    Chmielowiec J, Szlachcic WJ, Yang D, Scavuzzo MA, Wamble K, Sarrion-Perdigones A, Sabek OM, Venken KJT, Borowiak M
    Academic press:
    Nature Communications (rok: 2022, tom: 13(1), strony: 1952), Wydawca: Springer Nature Limited
    Status:
    Published
    DOI:
    10.1038/s41467-022-29646-1 - link to the publication