Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Non-canonical RNA tailing and other post-transcriptional regulatory mechanisms in T cell-mediated adaptive immunity.

2020/38/E/NZ2/00372

Keywords:

TENT5C Immunology Transcriptomics T cells non-canonical poly(A) polymerases adaptive immune response cytoplasmic polyadenylation Mus musculus

Descriptors:

  • NZ2_1: Molecular genetics
  • NZ6_1: Adaptive and innate immunity
  • NZ1_1: Molecular biology

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Uniwersytet Warszawski, Wydział Biologii

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Seweryn Mroczek 

Number of co-investigators in the project: 4

Call: SONATA BIS 10 - announced on 2020-07-29

Amount awarded: 3 499 920 PLN

Project start date (Y-m-d): 2021-03-22

Project end date (Y-m-d): 2026-03-21

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (9)
  • Book publications / chapters in book publications (1)
  1. A long non-coding RNA controls parasite differentiation in African trypanosomes
    Authors:
    Guegan F., Rajan K.S., Bento F., Neves D., Sequeira M., Gumińska N., Mroczek S., Dziembowski A., Cohen-Chalamish S., Doniger T., Galili B., Estévez A.M.,Notredame C., Michaeli S., Figueiredo L.M.
    Academic press:
    Science Advances , Wydawca: American Association for Advancement of Science
    Status:
    Submitted
  2. Three-layered control of mRNA poly(A) tail synthesis in Saccharomyces cerevisiae
    Authors:
    Matti Turtola, M Cemre Manav, Ananthanarayanan Kumar, Agnieszka Tudek, Seweryn Mroczek, Paweł S Krawczyk, Andrzej Dziembowski, Manfred Schmid, Lori A Passmore, Ana Casañal, Torben Heick Jensen
    Academic press:
    Genes & Development (rok: 2021, tom: 35, strony: 1290-1303), Wydawca: Cold Spring Harbor Laboratory Press
    Status:
    Published
    DOI:
    10.1101/GAD.348634.121 - link to the publication
  3. A long non-coding RNA controls parasite differentiation in African trypanosomes
    Authors:
    Guegan F., Rajan K.S., Bento F., Neves D., Sequeira M., Gumińska N., Mroczek S., Dziembowski A., Cohen-Chalamish S., Doniger T., Galili B., Estévez A.M.,Notredame C., Michaeli S., Figueiredo L.M.
    Academic press:
    Science Advances , Wydawca: American Association for Advancement of Science
    Status:
    Submitted
  4. Measuring the tail: Methods for poly(A) tail profiling
    Authors:
    Aleksandra Bilska, Paweł Krawczyk, Andrzej Dziembowski, Seweryn Mroczek
    Academic press:
    WIRE's RNA
    Status:
    Submitted
  5. A long non-coding RNA controls parasite differentiation in African trypanosomes
    Authors:
    Guegan F., Rajan K.S., Bento F., Neves D., Sequeira M., Gumińska N., Mroczek S., Dziembowski A., Cohen-Chalamish S., Doniger T., Galili B., Estévez A.M.,Notredame C., Michaeli S., Figueiredo L.M.
    Academic press:
    Science Advances , Wydawca: American Association for Advancement of Science
    Status:
    Submitted
  6. Measuring the tail: Methods for poly(A) tail profiling
    Authors:
    Aleksandra Brouze, Paweł Krawczyk, Andrzej Dziembowski, Seweryn Mroczek
    Academic press:
    Wiley Interdiscip Rev RNA (rok: 2023, tom: 14/1, strony: 45683), Wydawca: Wiley Periodicals LLC
    Status:
    Published
    DOI:
    10.1002/wrna.1737 - link to the publication
  7. Three-layered control of mRNA poly(A) tail synthesis in Saccharomyces cerevisiae
    Authors:
    Matti Turtola, M Cemre Manav, Ananthanarayanan Kumar, Agnieszka Tudek, Seweryn Mroczek, Paweł S Krawczyk, Andrzej Dziembowski, Manfred Schmid, Lori A Passmore, Ana Casañal, Torben Heick Jensen
    Academic press:
    Genes & Development (rok: 2021, tom: 35, strony: 1290-1303), Wydawca: Cold Spring Harbor Laboratory Press
    Status:
    Published
    DOI:
    10.1101/GAD.348634.121 - link to the publication
  8. Measuring the tail: Methods for poly(A) tail profiling
    Authors:
    Aleksandra Brouze, Paweł Krawczyk, Andrzej Dziembowski, Seweryn Mroczek
    Academic press:
    Wiley Interdiscip Rev RNA (rok: 2023, tom: 14/1, strony: 45683), Wydawca: Wiley Periodicals LLC
    Status:
    Published
    DOI:
    10.1002/wrna.1737 - link to the publication
  9. Three-layered control of mRNA poly(A) tail synthesis in Saccharomyces cerevisiae
    Authors:
    Matti Turtola, M Cemre Manav, Ananthanarayanan Kumar, Agnieszka Tudek, Seweryn Mroczek, Paweł S Krawczyk, Andrzej Dziembowski, Manfred Schmid, Lori A Passmore, Ana Casañal, Torben Heick Jensen
    Academic press:
    Genes & Development (rok: 2021, tom: 35, strony: 1290-1303), Wydawca: Cold Spring Harbor Laboratory Press
    Status:
    Published
    DOI:
    10.1101/gad.348634.121 - link to the publication
  1. Transcriptome-Wide Analysis of mRNA Adenylation Status in Yeast Using Nanopore Sequencing
    Authors:
    Pawel S Krawczyk, Agnieszka Tudek, Seweryn Mroczek, Andrzej Dziembowski
    Book:
    Methods in Molecular Biology. Deadenylation. (rok: 2023, tom: 13, strony: 193-214), Wydawca: Springer Link
    Status:
    Published
    DOI:
    10.1007/978-1-0716-3481-3_12 - link to the publication

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