Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Transcriptional and functional characterization of invasive breast cancercells isolated using novel in vivo reporter system.

2020/37/B/NZ5/03950

Keywords:

breast cancer invasion metastasis cancer stem cells epithelial-tomesenchymal transition EMT

Descriptors:

  • NZ5_5: Diagnostics in human diseases
  • NZ5_7: Human disease treatment
  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Agnieszka Kobielak 

Number of co-investigators in the project: 6

Call: OPUS 19 - announced on 2020-03-16

Amount awarded: 3 222 480 PLN

Project start date (Y-m-d): 2021-01-22

Project end date (Y-m-d): 2025-01-21

Project duration:: 48 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (7)
  1. Catulin Based Reporter System to Track and Characterize the Population of Invasive Cancer Cells in the Head and Neck Squamous Cell Carcinoma
    Authors:
    Karpińska K, Gielata M, Gwiazdowska A, Boryń Ł, Kobielak A.
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 23(1), strony: 140), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23010140 - link to the publication
  2. Catulin reporter marks a heterogeneous population of invasive breast cancer cells with some demonstrating plasticity and participating in vascular mimicry.
    Authors:
    Gielata M, Karpińska K, Gwiazdowska A, Boryń Ł, Kobielak A.
    Academic press:
    Scientific Reports (rok: 2022, tom: 12, strony: 12673), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-022-16802-2 - link to the publication
  3. Catulin Based Reporter System to Track and Characterize the Population of Invasive Cancer Cells in the Head and Neck Squamous Cell Carcinoma
    Authors:
    Karpińska K, Gielata M, Gwiazdowska A, Boryń Ł, Kobielak A.
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 23(1), strony: 140), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23010140 - link to the publication
  4. Emerging Roles of the α-Catenin Family Member α-Catulin in Development, Homeostasis and Cancer Progression.
    Authors:
    Gielata M, Karpińska K, Pieczonka T, Kobielak A
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23(19), strony: 11962), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms231911962 - link to the publication
  5. Catulin reporter marks a heterogeneous population of invasive breast cancer cells with some demonstrating plasticity and participating in vascular mimicry.
    Authors:
    Gielata M, Karpińska K, Gwiazdowska A, Boryń Ł, Kobielak A.
    Academic press:
    Scientific Reports (rok: 2022, tom: 12, strony: 12673), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-022-16802-2 - link to the publication
  6. Emerging Roles of the α-Catenin Family Member α-Catulin in Development, Homeostasis and Cancer Progression.
    Authors:
    Gielata M, Karpińska K, Pieczonka T, Kobielak A
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23(19), strony: 11962), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms231911962 - link to the publication
  7. Catulin Based Reporter System to Track and Characterize the Population of Invasive Cancer Cells in the Head and Neck Squamous Cell Carcinoma
    Authors:
    Karpińska K, Gielata M, Gwiazdowska A, Boryń Ł, Kobielak A.
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 23(1), strony: 140), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23010140 - link to the publication