Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Therapeutic activation and signalling determinants of the autoregulatory MBNL1 expression in myotonic dystrophy.

2020/37/B/NZ5/01263

Keywords:

Muscleblind-like 1 (MBNL1) myotonic dystrophy experimental therapy alternative splicing feedback loop signalling pathways transcription factors small activating RNA (saRNA) therapeutic RNA activation (RNAa)

Descriptors:

  • NZ5_7: Human disease treatment
  • NZ5_3: Pathogenesis of human diseases
  • NZ3_7: Signal transduction

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Ewa Stępniak-Konieczna 

Number of co-investigators in the project: 6

Call: OPUS 19 - announced on 2020-03-16

Amount awarded: 2 172 624 PLN

Project start date (Y-m-d): 2021-01-22

Project end date (Y-m-d): 2025-01-21

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.