Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Bioremediation of water pollution caused by drugs and cosmetics by Cunninghamella fungi - a biotechnological strategy for environmental clean-up

2020/37/B/NZ7/02546

Keywords:

bioremediation Cunninghamella drugs cosmetics environmental pollution

Descriptors:

  • NZ7_2: Environment and health risks
  • NZ7_15: Toxicology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński, Collegium Medicum

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Karolina Anna Słoczyńska 

Number of co-investigators in the project: 9

Call: OPUS 19 - announced on 2020-03-16

Amount awarded: 1 217 400 PLN

Project start date (Y-m-d): 2021-02-01

Project end date (Y-m-d): 2026-01-31

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (9)
  1. Antidepressant pharmaceuticals in aquatic systems, individual-level ecotoxicological effects: growth, survival and behavior
    Authors:
    Słoczyńska K, Orzeł J, Murzyn A, Popiół J, Gunia-Krzyżak A, Koczurkiewicz-Adamczyk P, Pękala E
    Academic press:
    Aquatic Toxicology (rok: 2023, tom: 260, strony: 106554), Wydawca: ScienceDirect
    Status:
    Published
    DOI:
    10.1016/j.aquatox.2023.106554 - link to the publication
  2. Cinnamamide derivatives with 4-hydroxypiperidine moiety enhance effect of doxorubicin to cancer cells and protect cardiomyocytes against drug-induced toxicity through CBR1 inhibition mechanism
    Authors:
    Koczurkiewicz-Adamczyk P, Gąsiorkiewicz B, Piska K, Gunia-Krzyżak A, Jamrozik M, Bucki A, Słoczyńska K, Bojdo P, Wójcik-Pszczoła K, Władyka B, Kołaczkowski M, Pękala E.
    Academic press:
    Life Sciences (rok: 2022, tom: 305, strony: 120777), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.lfs.2022.120777 - link to the publication
  3. In silico and in vitro ADME-Tox analysis and in vivo pharmacokinetic study of representative pan-PDE inhibitors from the group of 7,8-disubstituted derivatives of 1,3-dimethyl-7H-purine-2,6-dione
    Authors:
    Wójcik-Pszczoła K, Szafarz M, Pociecha K, Słoczyńska K, Piska K, Koczurkiewicz-Adamczyk P, Kocot N, Chłoń-Rzepa G, Pękala E, Wyska E.
    Academic press:
    Toxicology and Applied Pharmacology (rok: 2022, tom: 457, strony: 116318), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.taap.2022.116318 - link to the publication
  4. Antidepressant pharmaceuticals in aquatic systems, individual-level ecotoxicological effects: growth, survival and behavior
    Authors:
    Słoczyńska K, Orzeł J, Murzyn A, Popiół J, Gunia-Krzyżak A, Koczurkiewicz-Adamczyk P, Pękala E
    Academic press:
    Aquatic Toxicology (rok: 2023, tom: 260, strony: 106554), Wydawca: ScienceDirect
    Status:
    Published
    DOI:
    10.1016/j.aquatox.2023.106554 - link to the publication
  5. Biotransformation of oxybenzone and 3-(4-methylbenzylidene)camphor in Cunninghamella species: Potential for environmental clean-up of widely used sunscreen agents
    Authors:
    Murzyn A, Popiół J, Gunia-Krzyżak A, Żelaszczyk D, Dąbrówka B, Koczurkiewicz-Adamczyk P, Piska K, Żmudzki P, Pękala E, Słoczyńska K
    Academic press:
    Journal of Hazardous Materials (rok: 2025, tom: 489, strony: 137544), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jhazmat.2025.137544 - link to the publication
  6. In silico and in vitro ADME-Tox analysis and in vivo pharmacokinetic study of representative pan-PDE inhibitors from the group of 7,8-disubstituted derivatives of 1,3-dimethyl-7H-purine-2,6-dione
    Authors:
    Wójcik-Pszczoła K, Szafarz M, Pociecha K, Słoczyńska K, Piska K, Koczurkiewicz-Adamczyk P, Kocot N, Chłoń-Rzepa G, Pękala E, Wyska E.
    Academic press:
    Toxicology and Applied Pharmacology (rok: 2022, tom: 457, strony: 116318), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.taap.2022.116318 - link to the publication
  7. In silico and in vitro ADME-Tox analysis and in vivo pharmacokinetic study of representative pan-PDE inhibitors from the group of 7,8-disubstituted derivatives of 1,3-dimethyl-7H-purine-2,6-dione
    Authors:
    Wójcik-Pszczoła K, Szafarz M, Pociecha K, Słoczyńska K, Piska K, Koczurkiewicz-Adamczyk P, Kocot N, Chłoń-Rzepa G, Pękala E, Wyska E.
    Academic press:
    Toxicology and Applied Pharmacology (rok: 2022, tom: 457, strony: 116318), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.taap.2022.116318 - link to the publication
  8. Cinnamamide derivatives with 4-hydroxypiperidine moiety enhance effect of doxorubicin to cancer cells and protect cardiomyocytes against drug-induced toxicity through CBR1 inhibition mechanism
    Authors:
    Koczurkiewicz-Adamczyk P, Gąsiorkiewicz B, Piska K, Gunia-Krzyżak A, Jamrozik M, Bucki A, Słoczyńska K, Bojdo P, Wójcik-Pszczoła K, Władyka B, Kołaczkowski M, Pękala E.
    Academic press:
    Life Sciences (rok: 2022, tom: 305, strony: 120777), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.lfs.2022.120777 - link to the publication
  9. Cinnamamide derivatives with 4-hydroxypiperidine moiety enhance effect of doxorubicin to cancer cells and protect cardiomyocytes against drug-induced toxicity through CBR1 inhibition mechanism
    Authors:
    Koczurkiewicz-Adamczyk P, Gąsiorkiewicz B, Piska K, Gunia-Krzyżak A, Jamrozik M, Bucki A, Słoczyńska K, Bojdo P, Wójcik-Pszczoła K, Władyka B, Kołaczkowski M, Pękala E.
    Academic press:
    Life Sciences (rok: 2022, tom: 305, strony: 120777), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.lfs.2022.120777 - link to the publication

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