Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Individual biological response of breast cancer tumours to proton irradiation in correlation with molecular and microenvironmental factors.

2019/35/B/NZ7/04342

Keywords:

protonotherapy radiobiological response breast cancer

Descriptors:

  • NZ5_7: Human disease treatment
  • NZ7_16: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Julian Czesław Malicki 

Number of co-investigators in the project: 8

Call: OPUS 18 - announced on 2019-09-16

Amount awarded: 2 126 640 PLN

Project start date (Y-m-d): 2020-09-15

Project end date (Y-m-d): 2024-09-14

Project duration:: 48 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (9)
  1. Primary cancer-associated fibroblasts exhibit high heterogeneity among breast cancer subtypes
    Authors:
    Oliwia Piwocka, Marika Musielak, Igor Piotrowski, Katarzyna Kulcenty, Beata Adamczyk, Magdalena Fundowicz, Wiktoria Maria Suchorska, Julian Malicki
    Academic press:
    Reports of Practical Oncology and Radiotherapy (rok: 2023, tom: 28(2), strony: 159-171), Wydawca: Via Medica
    Status:
    Published
    DOI:
    10.5603/RPOR.a2023.0026 - link to the publication
  2. Ultra-Hypofractionated Proton Therapy in Localized Prostate Cancer: Passive Scattering versus Intensity-Modulated Proton Therapy
    Authors:
    D. M. Borowicz, K. N. Shipulin, G. V. Mytsin , A. Skrobała, P. Milecki, V. N. Gayevsky, V. Vondráček, J. Malicki.
    Academic press:
    Journal of Personalized Medicine (rok: 2021, tom: 11 (12), strony: 1311), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jpm11121311 - link to the publication
  3. Biological heterogeneity of primary cancer-associated fibroblast determines the breast cancer microenvironment.
    Authors:
    Musielak M, Piwócka O, Kulcenty K, Piotrowski I, Ampuła K, Adamczyk B, Fundowicz M, Kruszyna-Mochalska M, Suchorska WM, Malicki J.
    Academic press:
    American Journal of Cancer Research (rok: 2022, tom: 12(9), strony: 4411–4427), Wydawca: e-Century Publishing Corporation
    Status:
    Published
    DOI:
    link to the publication
  4. Biological heterogeneity of primary cancer-associated fibroblast determines the breast cancer microenvironment.
    Authors:
    Musielak M, Piwócka O, Kulcenty K, Piotrowski I, Ampuła K, Adamczyk B, Fundowicz M, Kruszyna-Mochalska M, Suchorska WM, Malicki J.
    Academic press:
    American Journal of Cancer Research (rok: 2022, tom: 12(9), strony: 4411–4427), Wydawca: e-Century Publishing Corporation
    Status:
    Published
    DOI:
    link to the publication
  5. Ultra-Hypofractionated Proton Therapy in Localized Prostate Cancer: Passive Scattering versus Intensity-Modulated Proton Therapy
    Authors:
    D. M. Borowicz, K. N. Shipulin, G. V. Mytsin , A. Skrobała, P. Milecki, V. N. Gayevsky, V. Vondráček, J. Malicki.
    Academic press:
    Journal of Personalized Medicine (rok: 2021, tom: 11 (12), strony: 1311), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jpm11121311 - link to the publication
  6. Navigating challenges: optimising methods for primary cell culture isolation
    Authors:
    O. Piwocka, M. Musielak, K. Ampuła, I. Piotrowski, B. Adamczyk, M. Fundowicz, W. M. Suchorska, J. Malicki
    Academic press:
    Cancer Cell International (rok: 2024, tom: 24, strony: 45669), Wydawca: Spring Nature
    Status:
    Published
    DOI:
    10.1186/s12935-023-03190-4 - link to the publication
  7. Future Perspectives of Proton Therapy in Minimizing theToxicity of Breast Cancer Radiotherapy
    Authors:
    Musielak M, Suchorska W, Fundowicz M, Milecki P, Malicki J.
    Academic press:
    Journal of Personalized Medicine (rok: 2021, tom: 11(5), strony: 410), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jpm11050410 - link to the publication
  8. Ultra-Hypofractionated Proton Therapy in Localized Prostate Cancer: Passive Scattering versus Intensity-Modulated Proton Therapy
    Authors:
    D. M. Borowicz, K. N. Shipulin, G. V. Mytsin , A. Skrobała, P. Milecki, V. N. Gayevsky, V. Vondráček, J. Malicki.
    Academic press:
    Journal of Personalized Medicine (rok: 2021, tom: 11 (12), strony: 1311), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jpm11121311 - link to the publication
  9. Future Perspectives of Proton Therapy in Minimizing theToxicity of Breast Cancer Radiotherapy
    Authors:
    Musielak M, Suchorska W, Fundowicz M, Milecki P, Malicki J.
    Academic press:
    Journal of Personalized Medicine (rok: 2021, tom: 11(5), strony: 410), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jpm11050410 - link to the publication

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