Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Strategies to protect against methamphetamine-induced neurotoxicity

2019/35/B/NZ7/03155

Keywords:

Physical activity inflammasome drugs neurogenesis neuroprotection neurotoxicity metabolome mitochondria

Descriptors:

  • NZ7_3: Physical culture and health promotion
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ7_15: Toxicology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Akademia Wychowania Fizycznego im. Jerzego Kukuczki w Katowicach, Instytut Fizjoterapii i Nauk o Zdrowiu

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Michał Jan Toborek 

Number of co-investigators in the project: 5

Call: OPUS 18 - announced on 2019-09-16

Amount awarded: 2 346 528 PLN

Project start date (Y-m-d): 2020-10-02

Project end date (Y-m-d): 2024-10-01

Project duration:: 48 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (12)
  • Articles in post-conference publications (3)
  1. Overcoming blood-brain barrier resistance: implications for extracellular vesicle-mediated drug brain delivery.
    Authors:
    Dardet JP, Serrano N, András IE, Toborek M.
    Academic press:
    Frontiers in Drug Delivery (rok: 2022, tom: 2, strony: 855017), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fddev.2022.855017 - link to the publication
  2. In-vivo targeting of the neurovascular unit: challenges and advancements.
    Authors:
    Naranjo O, Osborne O, Torices S, Toborek M.
    Academic press:
    Cellular and Molecular Neurobiology (rok: 2021, ), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10571-021-01113-3 - link to the publication
  3. Overcoming blood-brain barrier resistance: implications for extracellular vesicle-mediated drug brain delivery.
    Authors:
    Dardet JP, Serrano N, András IE, Toborek M.
    Academic press:
    Frontiers in Drug Delivery (rok: 2022, tom: 2, strony: 855017), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fddev.2022.855017 - link to the publication
  4. Synergistic impairment of the neurovascular unit by HIV-1 infection and methamphetamine use: implications for HIV-1-associated neurocognitive disorders.
    Authors:
    Fattakhov N, Torices S, Stangis M, Park M, Toborek M.
    Academic press:
    Viruses (rok: 2021, tom: 13, strony: 1883), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/v13091883 - link to the publication
  5. Synergistic impairment of the neurovascular unit by HIV-1 infection and methamphetamine use: implications for HIV-1-associated neurocognitive disorders.
    Authors:
    Fattakhov N, Torices S, Stangis M, Park M, Toborek M.
    Academic press:
    Viruses (rok: 2021, tom: 13, strony: 1883), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/v13091883 - link to the publication
  6. In-vivo targeting of the neurovascular unit: challenges and advancements.
    Authors:
    Naranjo O, Osborne O, Torices S, Toborek M.
    Academic press:
    Cellular and Molecular Neurobiology (rok: 2021, tom: 42, strony: 2131–2146), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10571-021-01113-3 - link to the publication
  7. Synergistic impairment of the neurovascular unit by HIV-1 infection and methamphetamine use: implications for HIV-1-associated neurocognitive disorders.
    Authors:
    Fattakhov N, Torices S, Stangis M, Park M, Toborek M.
    Academic press:
    Viruses (rok: 2021, tom: 13, strony: 1883), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/v13091883 - link to the publication
  8. In-vivo targeting of the neurovascular unit: challenges and advancements.
    Authors:
    Naranjo O, Osborne O, Torices S, Toborek M.
    Academic press:
    Cellular and Molecular Neurobiology (rok: 2021, tom: 42, strony: 2131–2146), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10571-021-01113-3 - link to the publication
  9. Overcoming blood-brain barrier resistance: implications for extracellular vesicle-mediated drug brain delivery.
    Authors:
    Dardet JP, Serrano N, András IE, Toborek M.
    Academic press:
    Frontiers in Drug Delivery (rok: 2022, tom: 2, strony: 855017), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fddev.2022.855017 - link to the publication
  10. Methamphetamine Enhances HIV-Induced Aberrant Proliferation of Neural Progenitor Cells via the FOXO3-Mediated Mechanism
    Authors:
    Park MS, Baker W, Cambow D, Gogerty D, Leda AR, Herlihy B, Pavlenko D, Van Den Nieuwenhuizen S, Toborek M.
    Academic press:
    Molecular Neurobiology (rok: 2021, tom: 58, strony: 5421–5436), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-021-02407-9 - link to the publication
  11. Methamphetamine Enhances HIV-Induced Aberrant Proliferation of Neural Progenitor Cells via the FOXO3-Mediated Mechanism
    Authors:
    Park MS, Baker W, Cambow D, Gogerty D, Leda AR, Herlihy B, Pavlenko D, Van Den Nieuwenhuizen S, Toborek M.
    Academic press:
    Molecular Neurobiology (rok: 2021, tom: 58, strony: 5421–5436), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-021-02407-9 - link to the publication
  12. Methamphetamine Enhances HIV-Induced Aberrant Proliferation of Neural Progenitor Cells via the FOXO3-Mediated Mechanism
    Authors:
    Park MS, Baker W, Cambow D, Gogerty D, Leda AR, Herlihy B, Pavlenko D, Van Den Nieuwenhuizen S, Toborek M.
    Academic press:
    Molecular Neurobiology (rok: 2021, tom: 58, strony: 5421–5436), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-021-02407-9 - link to the publication
  1. Methamphetamine induces cognitive decline via affecting the blood–brain barrier and aberrant proliferation and differentiation of neural progenitor cells.
    Authors:
    Park M, Liskiewicz A, Malecki A, Toborek M.
    Conference:
    Abstracts from the Virtual Symposium Signal Transduction at the Blood–Brain Barriers" (rok: 2021, tom: Signal Transduction at the Blood–Brain Barriers, strony: 18 (Suppl 1) 58, 10,), Wydawca: Springer Nature
    Data:
    konferencja 22-24 September 2021
    Status:
    Published
    DOI:
    10.1186/s12987-021-00286-9 - link to the publication
  2. Methamphetamine induces cognitive decline via affecting the blood–brain barrier and aberrant proliferation and differentiation of neural progenitor cells.
    Authors:
    Park M, Liskiewicz A, Malecki A, Toborek M.
    Conference:
    Abstracts from the Virtual Symposium Signal Transduction at the Blood–Brain Barriers" (rok: 2021, tom: Signal Transduction at the Blood–Brain Barriers, strony: 18 (Suppl 1) 58, 10,), Wydawca: Springer Nature
    Data:
    konferencja 22-24 September 2021
    Status:
    Published
    DOI:
    10.1186/s12987-021-00286-9 - link to the publication
  3. Methamphetamine induces cognitive decline via affecting the blood–brain barrier and aberrant proliferation and differentiation of neural progenitor cells.
    Authors:
    Park M, Liskiewicz A, Malecki A, Toborek M.
    Conference:
    Abstracts from the Virtual Symposium Signal Transduction at the Blood–Brain Barriers" (rok: 2021, tom: Signal Transduction at the Blood–Brain Barriers, strony: 18 (Suppl 1) 58, 10,), Wydawca: Springer Nature
    Data:
    konferencja 22-24 September 2021
    Status:
    Published
    DOI:
    10.1186/s12987-021-00286-9 - link to the publication

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