Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Improving therapeutic efficacy of anti-CD20 antibodies in precursor B-cell acute lymphoblastic leukemia

2019/35/B/NZ5/01428

Keywords:

acute lymphoblastic leukemia B cell CD20 therapy immunotherapy antibodies

Descriptors:

  • NZ5_007:
  • NZ6_001:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Małgorzata Firczuk 

Number of co-investigators in the project: 9

Call: OPUS 18 - announced on 2019-09-16

Amount awarded: 1 819 368 PLN

Project start date (Y-m-d): 2020-09-29

Project end date (Y-m-d): 2024-09-28

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (1)
  1. Mechanisms of Immune Evasion in Acute Lymphoblastic Leukemia
    Authors:
    Pastorczak A, Domka K, Fidyt K, Poprzeczko M, Firczuk M
    Academic press:
    Cancers (tom: 13(7):1536, strony: ), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13071536 - link to the publication
  2. Old and new targets for immunotherapy of B cell acute lymphoblastic leukemia
    Authors:
    Małgorzata Firczuk
    Academic press:
    Acta Haematologica Polonica (), Wydawca: Via Medica
    Status:
    Published
    DOI:
    10.5603/AHP.2021.0056 - link to the publication
  1. Optimizing the therapeutic potential of tyrosine kinase inhibitors in chemo-immunotherapy of B-cell acute lymphoblastic leukemia involving rituximab
    Authors:
    Krzysztof Domka; Martyna Poprzeczko; Zuzanna Urbanska; Lukasz Komorowski; Agata Pastorczak; Klaudyna Fidyt; Agnieszka Dabkowska; Mieszko Lachota; Magdalena Winiarska;Karolina Siudakowska; Elzbieta Patkowska; Łukasz Sędek; Bartosz Perkowski; Beata Krzymieniewska; Malgorzata Firczuk
    Conference:
    POSTER PRESENTATIONS - PROFFERED ABSTRACTS (tom: American Association for Cancer Research Annual Meeting 2022, Nowy Orlean, Luizjana, USA, strony: ), Wydawca: AACR
    Data:
    konferencja 8-13.04.2022
    Status:
    Published
    DOI:
    10.1158/1538-7445.AM2022-3324 - link to the publication