Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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A model of replication origin activation in response to replication stress and induction of premature mitoses, including the second round of the nuclear replication and division

2019/35/N/NZ3/03915

Keywords:

DNA replication replication origin replication stress replication fork genomic instability

Descriptors:

  • NZ3_1: Cell biology
  • NZ3_7: Signal transduction
  • NZ3_2: Cell physiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

Marcelina Weronika Musiałek 

Number of co-investigators in the project: 2

Call: PRELUDIUM 18 - announced on 2019-09-16

Amount awarded: 204 000 PLN

Project start date (Y-m-d): 2020-07-27

Project end date (Y-m-d): 2023-07-26

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (10)
  1. ATR-dependent activation of S-phase checkpoint: the influence of replication stress severity and duration on Cdc6 mediation
    Authors:
    Marcelina W. Musiałek, Dorota Rybaczek
    Academic press:
    Scientific Reports (rok: 2023, tom: n/a, strony: n/a), Wydawca: Springer Nature
    Status:
    Submitted
  2. Linking replication stress with replication dynamics in Vicia faba root meristem cells
    Authors:
    Marcelina W. Musiałek, Dorota Rybaczek
    Academic press:
    Scientific Reports (rok: 2023, tom: n/a, strony: n/a), Wydawca: Springer Nature
    Status:
    Submitted
  3. Adaptive changes of chromatin density and origin placement in Vicia faba root meristem cells subjected to replication stress
    Authors:
    Marcelina W. Musiałek, Dorota Rybaczek
    Academic press:
    eLife (rok: 2023, tom: n/a, strony: n/a), Wydawca: eLife
    Status:
    Submitted
  4. Hydroxyurea-The Good, the Bad and the Ugly
    Authors:
    Marcelina W Musiałek, Dorota Rybaczek
    Academic press:
    Genes (rok: 2021, tom: 12, strony: ), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/genes12071096 - link to the publication
  5. Hydroxyurea-The Good, the Bad and the Ugly
    Authors:
    Marcelina W Musiałek, Dorota Rybaczek
    Academic press:
    Genes (rok: 2021, tom: 12, strony: ), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/genes12071096 - link to the publication
  6. Hydroxyurea and Caffeine Impact pRb-like Protein-Dependent Chromatin Architecture Profiles in Interphase Cells of Vicia faba
    Authors:
    Marcelina W Musiałek, Joanna Deckert, Dorota Rybaczek
    Academic press:
    International Journal of Molecular Science (rok: 2021, tom: 22, strony: ), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22094572 - link to the publication
  7. Hydroxyurea and Caffeine Impact pRb-like Protein-Dependent Chromatin Architecture Profiles in Interphase Cells of Vicia faba
    Authors:
    Marcelina W Musiałek, Joanna Deckert, Dorota Rybaczek
    Academic press:
    International Journal of Molecular Science (rok: 2021, tom: 22, strony: ), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22094572 - link to the publication
  8. Hydroxyurea and Caffeine Impact pRb-like Protein-Dependent Chromatin Architecture Profiles in Interphase Cells of Vicia faba
    Authors:
    Marcelina W Musiałek, Joanna Deckert, Dorota Rybaczek
    Academic press:
    International Journal of Molecular Science (rok: 2021, tom: 22, strony: ), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22094572 - link to the publication
  9. Hydroxyurea-The Good, the Bad and the Ugly
    Authors:
    Marcelina W Musiałek, Dorota Rybaczek
    Academic press:
    Genes (rok: 2021, tom: 12, strony: ), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/genes12071096 - link to the publication
  10. Cdc6 activity analysis reveals possible unknown function in root meristem cells of Vicia faba
    Authors:
    Marcelina W. Musiałek, Dorota Rybaczek
    Academic press:
    Scientific Reports (rok: 2023, tom: n/a, strony: n/a), Wydawca: Springer Nature
    Status:
    Submitted

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