Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Research on molecular mechanisms of functions of pathogenesis-related proteins of Chelidonium majus latex

2019/35/B/NZ9/03851

Keywords:

Chelidonium majus plant defense proteins pathogenesis-related PR proteins milky sap antiviral activity

Descriptors:

  • NZ9_9: Environmental biotechnology
  • NZ6_5: Virology
  • NZ2_3: Proteomics

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Robert Nawrot 

Number of co-investigators in the project: 6

Call: OPUS 18 - announced on 2019-09-16

Amount awarded: 1 712 520 PLN

Project start date (Y-m-d): 2020-07-20

Project end date (Y-m-d): 2026-07-19

Project duration:: 72 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (17)
  • Book publications / chapters in book publications (4)
  1. Przeciwwirusowe związki izolowane z roślin
    Authors:
    Robert Nawrot, Alicja Warowicka, Oskar Musidlak, Martyna Węglewska, Sophia Bałdysz, Anna Goździcka-Józefiak
    Academic press:
    Postępy Biochemii (rok: 2021, tom: 66, strony: 356-372), Wydawca: Polskie Towarzystwo Biochemiczne
    Status:
    Published
    DOI:
    10.18388/pb.2020_361 - link to the publication
  2. Combined Protein and Alkaloid Research of Chelidonium majus Latex Reveals CmMLP1 Accompanied by Alkaloids with Cytotoxic Potential to Human Cervical Carcinoma Cells
    Authors:
    Robert Nawrot, Alicja Warowicka, Piotr Józef Rudzki, Oskar Musidlak, Katarzyna Magdalena Dolata, Jacek Musijowski, Elżbieta Urszula Stolarczyk, Anna Goździcka-Józefiak
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 11838), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222111838 - link to the publication
  3. Functional Studies of Plant Latex as a Rich Source of Bioactive Compounds: Focus on Proteins and Alkaloids
    Authors:
    Joanna Gracz-Bernaciak, Oliwia Mazur, Robert Nawrot
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 12427), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222212427 - link to the publication
  4. Combined Protein and Alkaloid Research of Chelidonium majus Latex Reveals CmMLP1 Accompanied by Alkaloids with Cytotoxic Potential to Human Cervical Carcinoma Cells
    Authors:
    Robert Nawrot, Alicja Warowicka, Piotr Józef Rudzki, Oskar Musidlak, Katarzyna Magdalena Dolata, Jacek Musijowski, Elżbieta Urszula Stolarczyk, Anna Goździcka-Józefiak
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 11838), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222111838 - link to the publication
  5. Combined Protein and Alkaloid Research of Chelidonium majus Latex Reveals CmMLP1 Accompanied by Alkaloids with Cytotoxic Potential to Human Cervical Carcinoma Cells
    Authors:
    Robert Nawrot, Alicja Warowicka, Piotr Józef Rudzki, Oskar Musidlak, Katarzyna Magdalena Dolata, Jacek Musijowski, Elżbieta Urszula Stolarczyk, Anna Goździcka-Józefiak
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 11838), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222111838 - link to the publication
  6. Tap the sap – investigation of latex-bearing plants in the search of potential anticancer biopharmaceuticals
    Authors:
    Oliwia Mazur, Sophia Bałdysz, Alicja Warowicka, Robert Nawrot
    Academic press:
    Frontiers in Plant Science (rok: 2022, tom: 13, strony: 45681), Wydawca: Frontiers Media S.A.
    Status:
    Published
    DOI:
    10.3389/fpls.2022.979678 - link to the publication
  7. Przeciwwirusowe związki izolowane z roślin
    Authors:
    Robert Nawrot, Alicja Warowicka, Oskar Musidlak, Martyna Węglewska, Sophia Bałdysz, Anna Goździcka-Józefiak
    Academic press:
    Postępy Biochemii (rok: 2021, tom: 66, strony: 356-372), Wydawca: Polskie Towarzystwo Biochemiczne
    Status:
    Published
    DOI:
    10.18388/pb.2020_361 - link to the publication
  8. Tap the sap – investigation of latex-bearing plants in the search of potential anticancer biopharmaceuticals
    Authors:
    Oliwia Mazur, Sophia Bałdysz, Alicja Warowicka, Robert Nawrot
    Academic press:
    Frontiers in Plant Science (rok: 2022, tom: 13, strony: 45681), Wydawca: Frontiers Media S.A.
    Status:
    Published
    DOI:
    10.3389/fpls.2022.979678 - link to the publication
  9. Herbgenomics meets Papaveraceae: a promising -omics perspective on medicinal plant research
    Authors:
    Kielich Natalia Anna, Mazur Oliwia, Musidlak Oskar, Gracz-Bernaciak Joanna, Nawrot Robert
    Academic press:
    Briefings in Functional Genomics (rok: 2023, tom: elad050, strony: 45673), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/bfgp/elad050 - link to the publication
  10. Tap the sap – investigation of latex-bearing plants in the search of potential anticancer biopharmaceuticals
    Authors:
    Oliwia Mazur, Sophia Bałdysz, Alicja Warowicka, Robert Nawrot
    Academic press:
    Frontiers in Plant Science (rok: 2022, tom: 13, strony: 45681), Wydawca: Frontiers Media S.A.
    Status:
    Published
    DOI:
    10.3389/fpls.2022.979678 - link to the publication
  11. Przeciwwirusowe związki izolowane z roślin
    Authors:
    Robert Nawrot, Alicja Warowicka, Oskar Musidlak, Martyna Węglewska, Sophia Bałdysz, Anna Goździcka-Józefiak
    Academic press:
    Postępy Biochemii (rok: 2021, tom: 66, strony: 356-372), Wydawca: Polskie Towarzystwo Biochemiczne
    Status:
    Published
    DOI:
    10.18388/pb.2020_361 - link to the publication
  12. Combined Protein and Alkaloid Research of Chelidonium majus Latex Reveals CmMLP1 Accompanied by Alkaloids with Cytotoxic Potential to Human Cervical Carcinoma Cells
    Authors:
    Robert Nawrot, Alicja Warowicka, Piotr Józef Rudzki, Oskar Musidlak, Katarzyna Magdalena Dolata, Jacek Musijowski, Elżbieta Urszula Stolarczyk, Anna Goździcka-Józefiak
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 11838), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222111838 - link to the publication
  13. Functional Studies of Plant Latex as a Rich Source of Bioactive Compounds: Focus on Proteins and Alkaloids
    Authors:
    Joanna Gracz-Bernaciak, Oliwia Mazur, Robert Nawrot
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 12427), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222212427 - link to the publication
  14. Herbgenomics meets Papaveraceae: a promising -omics perspective on medicinal plant research
    Authors:
    Kielich Natalia Anna, Mazur Oliwia, Musidlak Oskar, Gracz-Bernaciak Joanna, Nawrot Robert
    Academic press:
    Briefings in Functional Genomics (rok: 2023, tom: elad050, strony: 45673), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/bfgp/elad050 - link to the publication
  15. Przeciwwirusowe związki izolowane z roślin
    Authors:
    Robert Nawrot, Alicja Warowicka, Oskar Musidlak, Martyna Węglewska, Sophia Bałdysz, Anna Goździcka-Józefiak
    Academic press:
    Postępy Biochemii (rok: 2021, tom: 66, strony: 356-372), Wydawca: Polskie Towarzystwo Biochemiczne
    Status:
    Published
    DOI:
    10.18388/pb.2020_361 - link to the publication
  16. Functional Studies of Plant Latex as a Rich Source of Bioactive Compounds: Focus on Proteins and Alkaloids
    Authors:
    Joanna Gracz-Bernaciak, Oliwia Mazur, Robert Nawrot
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 12427), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222212427 - link to the publication
  17. Functional Studies of Plant Latex as a Rich Source of Bioactive Compounds: Focus on Proteins and Alkaloids
    Authors:
    Joanna Gracz-Bernaciak, Oliwia Mazur, Robert Nawrot
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 12427), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222212427 - link to the publication
  1. Chapter Ten - Traditional use and perspectives for the application of plant latex and its constituents in agriculture, medicine and industry—A follow-up of ABR volume 93 Latex, laticifers and their molecular components from functions to possible applications"
    Authors:
    Robert Nawrot, Oskar Musidlak, Sophia Bałdysz, Martyna Węglewska, Alicja Warowicka, Anna Goździcka-Józefiaka
    Book:
    Advances in Botanical Research, Volume 100 (rok: 2021, tom: 100, strony: 301-327), Wydawca: Academic Press - Elsevier Ltd
    Status:
    Published
    DOI:
    10.1016/bs.abr.2021.01.006 - link to the publication
  2. Chapter Ten - Traditional use and perspectives for the application of plant latex and its constituents in agriculture, medicine and industry—A follow-up of ABR volume 93 Latex, laticifers and their molecular components from functions to possible applications"
    Authors:
    Robert Nawrot, Oskar Musidlak, Sophia Bałdysz, Martyna Węglewska, Alicja Warowicka, Anna Goździcka-Józefiaka
    Book:
    Advances in Botanical Research, Volume 100 (rok: 2021, tom: 100, strony: 301-327), Wydawca: Academic Press - Elsevier Ltd
    Status:
    Published
    DOI:
    10.1016/bs.abr.2021.01.006 - link to the publication
  3. Chapter Ten - Traditional use and perspectives for the application of plant latex and its constituents in agriculture, medicine and industry—A follow-up of ABR volume 93 Latex, laticifers and their molecular components from functions to possible applications"
    Authors:
    Robert Nawrot, Oskar Musidlak, Sophia Bałdysz, Martyna Węglewska, Alicja Warowicka, Anna Goździcka-Józefiaka
    Book:
    Advances in Botanical Research, Volume 100 (rok: 2021, tom: 100, strony: 301-327), Wydawca: Academic Press - Elsevier Ltd
    Status:
    Published
    DOI:
    10.1016/bs.abr.2021.01.006 - link to the publication
  4. Chapter Ten - Traditional use and perspectives for the application of plant latex and its constituents in agriculture, medicine and industry—A follow-up of ABR volume 93 Latex, laticifers and their molecular components from functions to possible applications"
    Authors:
    Robert Nawrot, Oskar Musidlak, Sophia Bałdysz, Martyna Węglewska, Alicja Warowicka, Anna Goździcka-Józefiaka
    Book:
    Advances in Botanical Research, Volume 100 (rok: 2021, tom: 100, strony: 301-327), Wydawca: Academic Press - Elsevier Ltd
    Status:
    Published
    DOI:
    10.1016/bs.abr.2021.01.006 - link to the publication

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