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In search of spectroscopic markers of autophagy based on pharmacologically induced phospholipidosis in endothelial cells

2019/35/N/ST4/03896

Keywords:

Raman imaging lipids endothelial cells phospholipidosis

Descriptors:

  • ST4_2: Spectroscopic and spectrometric techniques
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • ST4_9: Biological chemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

Ewelina Joanna Bik 

Number of co-investigators in the project: 2

Call: PRELUDIUM 18 - announced on 2019-09-16

Amount awarded: 210 000 PLN

Project start date (Y-m-d): 2020-07-27

Project end date (Y-m-d): 2023-07-26

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (6)
  1. Chloroquine-Induced Accumulation of Autophagosomes and Lipids in the Endothelium
    Authors:
    Ewelina Bik, Lukasz Mateuszuk, Jagoda Orleanska, Malgorzata Baranska, Stefan Chlopicki, Katarzyna Majzner
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 2401), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22052401 - link to the publication
  2. Chloroquine-Induced Accumulation of Autophagosomes and Lipids in the Endothelium
    Authors:
    Ewelina Bik, Lukasz Mateuszuk, Jagoda Orleanska, Malgorzata Baranska, Stefan Chlopicki, Katarzyna Majzner
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 2401), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22052401 - link to the publication
  3. Chloroquine-Induced Accumulation of Autophagosomes and Lipids in the Endothelium
    Authors:
    Ewelina Bik, Lukasz Mateuszuk, Jagoda Orleanska, Malgorzata Baranska, Stefan Chlopicki, Katarzyna Majzner
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 2401), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22052401 - link to the publication
  4. Raman and fluorescence imaging of phospholipidosis induced by cationic amphiphilic drugs in endothelial cells
    Authors:
    Ewelina Bik, Jagoda Orleanska, Lukasz Mateuszuk, Malgorzata Baranska, Katarzyna Majzner, Stefan Chlopicki
    Academic press:
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (rok: 2022, tom: 1869, strony: 119186), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2021.119186 - link to the publication
  5. Raman and fluorescence imaging of phospholipidosis induced by cationic amphiphilic drugs in endothelial cells
    Authors:
    Ewelina Bik, Jagoda Orleanska, Lukasz Mateuszuk, Malgorzata Baranska, Katarzyna Majzner, Stefan Chlopicki
    Academic press:
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (rok: 2022, tom: 1869, strony: 119186), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2021.119186 - link to the publication
  6. Raman and fluorescence imaging of phospholipidosis induced by cationic amphiphilic drugs in endothelial cells
    Authors:
    Ewelina Bik, Jagoda Orleanska, Lukasz Mateuszuk, Malgorzata Baranska, Katarzyna Majzner, Stefan Chlopicki
    Academic press:
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (rok: 2022, tom: 1869, strony: 119186), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2021.119186 - link to the publication

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