Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Searching for UDP-GlcNAc delivery routes - a crucial substrate for eukariotic cell glycosylation

2019/35/B/NZ3/00481

Keywords:

glycosylation UDP-N-acetyl-glucosamine membrane transport SLC35A3

Descriptors:

  • NZ3_2: Cell physiology
  • NZ1_2: Biochemistry
  • NZ1_7: Cell engineering

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Wrocławski, Wydział Biotechnologii

woj.

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Mariusz Olczak 

Number of co-investigators in the project: 9

Call: OPUS 18 - announced on 2019-09-16

Amount awarded: 1 847 040 PLN

Project start date (Y-m-d): 2020-07-28

Project end date (Y-m-d): 2024-07-27

Project duration:: 48 months (the same as in the proposal)

Project status: Project completed

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (6)
  1. Delivery of Nucleotide Sugars to the Mammalian Golgi: A Very Well (un)Explained Story
    Authors:
    Maszczak-Seneczko D, Wiktor M, Skurska E, Wiertelak W, Olczak M
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23(15), strony: 8648), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23158648 - link to the publication
  2. Identification of novel potential interaction partners of UDP galactose (SLC35A2), UDP-N-acetylglucosamine (SLC35A3) and an orphan (SLC35A4) nucleotide sugar transporters
    Authors:
    MaciejWiktor, Wojciech Wiertelak, Dorota Maszczak-Seneczko, Piotr Jan Balwierz, Bożena Szulc, Mariusz Olczak
    Academic press:
    Journal of Proteomics (rok: 2021, tom: 249, strony: 104321), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jprot.2021.104321 - link to the publication
  3. The glycosylation defect in solute carrier SLC35A2/SLC35A3 double knockout cells is rescued by SLC35A2-SLC35A3 and SLC35A3-SLC35A2 hybrids
    Authors:
    Wojciech Wiertelak, Artem Pavlovskyi, Dorota Maszczak-Seneczko, Bozena Szulc and _ Mariusz Olczak
    Academic press:
    FEBS Letters (rok: 2023, tom: 597, strony: 2345-57), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/1873-3468.14714 - link to the publication
  4. Identification of novel potential interaction partners of UDP galactose (SLC35A2), UDP-N-acetylglucosamine (SLC35A3) and an orphan (SLC35A4) nucleotide sugar transporters
    Authors:
    MaciejWiktor, Wojciech Wiertelak, Dorota Maszczak-Seneczko, Piotr Jan Balwierz, Bożena Szulc, Mariusz Olczak
    Academic press:
    Journal of Proteomics (rok: 2021, tom: 249, strony: 104321), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jprot.2021.104321 - link to the publication
  5. Identification of novel potential interaction partners of UDP galactose (SLC35A2), UDP-N-acetylglucosamine (SLC35A3) and an orphan (SLC35A4) nucleotide sugar transporters
    Authors:
    MaciejWiktor, Wojciech Wiertelak, Dorota Maszczak-Seneczko, Piotr Jan Balwierz, Bożena Szulc, Mariusz Olczak
    Academic press:
    Journal of Proteomics (rok: 2021, tom: 249, strony: 104321), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jprot.2021.104321 - link to the publication
  6. Delivery of Nucleotide Sugars to the Mammalian Golgi: A Very Well (un)Explained Story
    Authors:
    Maszczak-Seneczko D, Wiktor M, Skurska E, Wiertelak W, Olczak M
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23(15), strony: 8648), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23158648 - link to the publication